Clinical trials
Mastectomy clinical trials
Below are recruiting mastectomy clinical trials, each written for real people, not researchers. We’re tracking 123 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07510698Recruiting
Same-day awake mastectomy with immediate breast reconstruction
This study tests whether people can have a mastectomy while awake (using numbing medicine instead of general anesthesia) and go home the same day with immediate breast reconstruction. It may be an option if you're healthy enough and have support at home.
Rome, RomeAges 18–75 - NCT07556952RecruitingPhase 4
Dexamethasone to reduce pain after breast removal surgery
This study tests whether dexamethasone (a common anti-inflammatory medication) can reduce pain after mastectomy (surgical removal of breast tissue). Researchers want to see if it helps patients recover with less pain and potentially fewer pain medications.
Montreal, QuebecAges 18–75 - NCT07561411Recruiting
Nerve blocks to reduce pain after breast removal surgery
This trial tests two types of nerve-blocking injections given during breast removal surgery to see which one better prevents long-term pain afterward. Both are given alongside general anesthesia and may help you recover with less chronic pain.
BeirutAges 18–80 - NCT07653152Recruiting
Endoscopic vs open surgery for male breast reduction
This study compares two surgical approaches for removing male breast gland tissue in men with gynecomastia. One method uses small cuts and a camera (endoscopic), the other uses a standard cut (open surgery) – both aim to preserve the nipple and areola.
AntalyaAges 18–60 - NCT07352137Enrolling by invitation
Endoscopic Nipple-Sparing Mastectomy with Fat Grafting for Breast Reconstruction
This trial tests a new way to remove the breast through a small cut in the armpit (endoscopic nipple-sparing mastectomy) and immediately rebuild the breast using your own fat. It's for women with early-stage breast cancer who want to keep their nipple and have reconstruction at the same time.
Guanzhou, GuangdongAges 18–70 - NCT05444361Enrolling by invitation
Ultrasound freezing treatment for pain after mastectomy
This trial tests a “freezing” nerve procedure guided by ultrasound to help reduce pain after mastectomy. It aims to lessen postoperative pain by temporarily calming specific nerves involved in chest wall sensation.
Los Angeles, CaliforniaAges 18 years+ - NCT05072314RecruitingPhase 3
Lidocaine drip after breast surgery to improve long-term pain
This Phase 3 study tests whether a long-running lidocaine (a numbing medicine) drip given around the time of breast surgery can improve long-term post-surgery pain and recovery. It may help people who have pain after mastectomy or breast-conserving surgery.
Kingswood, New South WalesAges 18 years+ - NCT07739277Recruiting
Comparing two ways to give a chest wall pain block for breast surgery
This study compares two ways of giving a numbing injection (a nerve block) to the side of the chest wall for pain relief after breast surgery. The goal is to see which method works better for reducing pain and the need for pain medicine.
Ankara, Yenimahalle\AnkaraAges 18–65 - NCT05794321RecruitingPhase 2
IV tranexamic acid during gender-affirming chest surgery
This Phase 2 study tests whether giving tranexamic acid through a vein during gender-affirming mastectomy can safely reduce bleeding. It may help lower blood loss and related complications during surgery.
San Francisco, CaliforniaAges 18 years+ - NCT06982391Enrolling by invitation
Support program for breast cancer survivors
This study tests a program designed to help women who have had a mastectomy feel more supported and resilient. It may be a good fit if you are a breast cancer survivor interested in emotional and social support.
IstanbulAges 18–65 - NCT06080620Recruiting
Choosing the best treatment for locally advanced breast cancer
This study looks at different treatment plans for women with newly diagnosed, locally advanced breast cancer (stage IIIb-IIIc). It aims to find the most effective combination of surgery, chemotherapy, and radiotherapy. If you are a woman aged 18-70 with this diagnosis and your tumor can be surgically removed, this trial may be an option for you.
BeijingAges 18–70 - NCT05460780Recruiting
Tissue device study for breast reconstruction after mastectomy
This first-time-in-humans study tests a tissue-engineering chamber called MATTISSE® to help the healing of breast reconstruction using specific tissue flaps after mastectomy for cancer. If you qualify, you would be assessed for safety and how well the reconstructed tissue heals.
Strasbourg, FranceAges 18 years+ - NCT05585710Recruiting
Study pulsed rinse during breast implant reconstruction
This trial tests whether a special “pulsed rinse” technique during implant-based breast reconstruction improves care during surgery. If you’re having immediate expander placement at the time of mastectomy, you may be eligible to try this approach under research oversight.
Birmingham, AlabamaAges 18–75 - NCT04891510Recruiting
Compare fat grafting products in breast surgery
This trial compares three methods for moving your own fat into the breast during breast surgery. It may help improve how well fat grafting works and how surgeons choose the best method for you.
New York, New YorkAges 18 years+ - NCT06748677Recruiting
Nipple-sparing mastectomy with robotic help and implant reconstruction
This trial tests a newer, less invasive way to remove breast tissue while keeping the nipple and skin, using robotic or endoscopic tools. It then rebuilds the breast with an implant wrapped in a non-biological mesh. The goal is to see how well patients recover and how they feel about the results.
Beijing, Beijing MunicipalityAges Any age - NCT05975359Recruiting
Testing a fluid-drain device during breast implant reconstruction
This study tests a new way to measure and manage fluid drainage during immediate breast reconstruction with implants. It may help surgeons reduce complications and improve the reconstruction experience after mastectomy.
Palo Alto, CaliforniaAges 18–65 - NCT07071896Recruiting
Video exercise program for breast cancer survivors
This study tests a video-based exercise program for people who recently had breast cancer surgery. It aims to help with recovery by providing guided exercises you can do at home.
San Diego, CaliforniaAges 18 years+ - NCT07607366Recruiting
Negative Pressure Bandaging After Breast Removal Surgery
This trial tests a special bandage that uses gentle suction to help wounds heal better after breast cancer surgery. Researchers want to see if this type of bandaging reduces complications like fluid buildup and improves healing.
FalunAges 18 years+ - NCT06502353Recruiting
Plexaa before gender-affirming mastectomy
This trial tests a product called Plexaa, which is applied before surgery to help prepare the skin and improve healing. It is for transgender or non-binary people having a specific type of mastectomy (breast removal) for gender affirmation.
Palo Alto, CaliforniaAges 18 years+ - NCT06512259Recruiting
AlloMend tissue support in breast reconstruction after mastectomy
This study tests a special tissue support called AlloMend used during breast reconstruction after mastectomy. It helps see how well the tissue works and how patients heal.
Joliet, IllinoisAges 18 years+ - NCT07261904Recruiting
Study of a medical tattoo for nipple reconstruction
This trial tests a medical tattoo called BIOCHROMADERM® for women or men who need a nipple-areola tattoo after breast reconstruction surgery. It checks if the tattoo is safe and works well.
LilleAges 18 years+ - NCT06921148Recruiting
Silk bandage for gender-affirming mastectomy recovery
This trial tests a silk protein bandage for people having double-incision mastectomy as part of female-to-male gender affirmation surgery. The goal is to see if this special bandage helps wounds heal better.
Indianapolis, IndianaAges 18 years+ - NCT06890221Recruiting
Nutrition therapy before and after breast cancer surgery
This trial tests if a special nutrition drink before and after mastectomy can help breast cancer patients recover better. It uses a body measurement called bioimpedance phase angle to see how nutrition affects your cells and healing.
Petaling Jaya, Kuala LumpurAges 18 years+ - NCT06774352Recruiting
Prosthetic breast reconstruction after mastectomy
This trial studies breast reconstruction using implants after mastectomy (breast removal surgery). It aims to understand how different types of implants work and how patients recover.
BolognaAges 18–70
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Common questions
- Are there clinical trials for mastectomy?
- Yes. Clin2 currently lists 123 recruiting mastectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mastectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mastectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.