Clinical trials
Mastectomy clinical trials
Below are recruiting mastectomy clinical trials, each written for real people, not researchers. We’re tracking 117 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05412225RecruitingPhase 1
Pre-surgery radiation, then mastectomy and immediate breast reconstruction
This Phase 1 study looks at giving radiation before surgery for people with locally advanced breast cancer, then performing a mastectomy and immediate reconstruction. It aims to see whether this combined approach can shrink the cancer before surgery and safely allow reconstruction afterward.
Basking Ridge, New JerseyAges 18 years+ - NCT04666961RecruitingPhase 2
Hormone therapy before surgery for extensive DCIS
This Phase 2 study tests whether taking hormone medicine before surgery can change the surgical plan and outcomes for people with extensive ductal carcinoma in situ (DCIS). It is for estrogen-receptor positive DCIS and aims to see how this “neoadjuvant” approach affects treatment decisions.
AngersAges 40 years+ - NCT05833659Recruiting
Comparing two breast reconstruction positions after mastectomy
This trial compares two surgical techniques for breast reconstruction: placing the implant under the chest muscle versus in front of it. It may help people understand which approach works better for comfort and healing after mastectomy.
Beijing, Beijing MunicipalityAges 18–70 - NCT04687956Recruiting
Preventing arm swelling after breast cancer lymph node surgery
This study looks at ways to prevent arm swelling (lymphedema) related to breast cancer after surgery to remove lymph nodes. It may help people who are getting axillary lymph node dissection lower the chance of long-term swelling.
SeoulAges 19 years+ - NCT04741737Recruiting
Repeat lymph node biopsy for recurrent breast cancer
This study tests whether repeating a specific lymph node biopsy (sentinel lymph node biopsy) is safe and useful in people whose breast cancer has come back in the same breast. It may help doctors better understand whether lymph nodes are involved and guide next steps after surgery.
SeoulAges 19 years+ - NCT07821593Recruiting
Experiences after preventive mastectomy for BRCA gene carriers
This study asks women who carry a BRCA1 or BRCA2 gene change and chose to have their breasts removed to prevent cancer about their experiences after surgery. Participation involves filling out a survey about your feelings and recovery.
Pavia, PaviaAges 25–70 - NCT07739277Recruiting
Comparing two ways to give a chest wall pain block for breast surgery
This study compares two ways of giving a numbing injection (a nerve block) to the side of the chest wall for pain relief after breast surgery. The goal is to see which method works better for reducing pain and the need for pain medicine.
Ankara, Yenimahalle\AnkaraAges 18–65 - NCT06166953Recruiting
Smartphone education for breast reconstruction recovery
This study tests if a smartphone-based education program helps women who are recovering from breast reconstruction surgery after a mastectomy. If you are a Turkish speaker with a compatible smartphone, you may be able to join.
Ankara, ÇankayaAges 18–75 - NCT07659990Recruiting
Comparing two nerve blocks for mastectomy pain relief
This study compares two types of nerve blocks given before a mastectomy (breast removal surgery) to see which one provides better pain relief. If you are having a mastectomy on one side with lymph node removal, you may be able to join.
Bursa, NilüferAges 18–75 - NCT07650305Recruiting
Pain Relief Methods After Breast Cancer Surgery
This trial compares two different nerve-blocking techniques (numbing methods) to reduce pain after breast cancer surgery. Both approaches aim to keep you comfortable during and after your operation.
CairoAges 18–65 - NCT07641985Recruiting
Fat grafting for breast reconstruction after cancer and radiation
This study compares two ways to rebuild the breast after mastectomy and radiation using your own tissue: fat grafting alone, or a more complex surgery using abdominal tissue. The goal is to see which method gives better results and quality of life.
Maastricht, LimburgAges 18 years+ - NCT06252662RecruitingPhase 4
Comparing two numbing medicines for mastectomy nerve blocks
This study compares two types of numbing medicine given through a nerve block before a mastectomy. One is a long-acting version (liposomal bupivacaine) and the other is a standard numbing medicine combined with a sedative (bupivacaine with dexmedetomidine). The goal is to see which provides better pain relief after surgery.
Portsmouth, VirginiaAges 18 years+ - NCT07607366Recruiting
Negative Pressure Bandaging After Breast Removal Surgery
This trial tests a special bandage that uses gentle suction to help wounds heal better after breast cancer surgery. Researchers want to see if this type of bandaging reduces complications like fluid buildup and improves healing.
FalunAges 18 years+ - NCT06717984Recruiting
AI model for breast cancer from tissue images
This trial tests an artificial intelligence (AI) model that looks at pictures of breast tissue to find cancer. It may help improve early detection and reduce the need for invasive tests.
DhakaAges Any age - NCT07586319Enrolling by invitation
Surgery to improve survival in early-stage spread breast cancer
This study tests whether surgery to remove cancer spots can help people with breast cancer that has spread to a few places live longer. You would receive standard cancer medicines plus surgery if you qualify.
Lahore, Punjab ProvinceAges 18 years+ - NCT07578116RecruitingPhase 3
Adding surgery and radiation for her2-positive breast cancer with a few spread spots
This trial tests whether adding surgery and radiation to the usual HER2-targeted treatment helps people with breast cancer that has spread to a few spots. You must have HER2-positive cancer that is newly spread, and you must be able to receive radiation to all tumor sites.
Jonesboro, ArkansasAges 18 years+ - NCT07579650Recruiting
Nerve Block for Pain Relief After Breast Surgery
This trial tests a special numbing technique (called a serratus posterior superior intercostal plane block) to help reduce pain after mastectomy surgery. The goal is to see if this nerve block reduces the need for pain medications after your procedure.
Diyarbakır, Outside of the USAges 18–65 - NCT07576270Recruiting
Breathing exercises and massage after breast cancer surgery
This study tests whether special breathing exercises and massage techniques can help reduce pain, stiffness, and limited arm movement in people who've had breast cancer surgery. It may help improve shoulder function and quality of life after treatment.
Lahore, Punjab ProvinceAges 45–64 - NCT07512141Recruiting
Single vs. Double Drains After Breast Cancer Surgery
This study compares using one drain versus two drains to collect fluid after breast cancer removal surgery. The goal is to see which approach works better and causes fewer problems during recovery.
Karachi, SindhAges 18–70 - NCT06748677Recruiting
Nipple-sparing mastectomy with robotic help and implant reconstruction
This trial tests a newer, less invasive way to remove breast tissue while keeping the nipple and skin, using robotic or endoscopic tools. It then rebuilds the breast with an implant wrapped in a non-biological mesh. The goal is to see how well patients recover and how they feel about the results.
Beijing, Beijing MunicipalityAges Any age - NCT06774352Recruiting
Prosthetic breast reconstruction after mastectomy
This trial studies breast reconstruction using implants after mastectomy (breast removal surgery). It aims to understand how different types of implants work and how patients recover.
BolognaAges 18–70 - NCT07463430Enrolling by invitationPhase 4
Suzetrigine for pain after non-mastectomy breast surgery
This trial tests a new pain medication, suzetrigine, for people having breast surgery (not mastectomy) who are expected to have moderate pain. It checks if this drug works well compared to standard options.
San Diego, CaliforniaAges 18 years+ - NCT07446868Recruiting
Comparing two nerve blocks for pain after mastectomy
This trial compares two nerve-block techniques (SPSIP and ESPB) to see which one provides better pain relief after breast cancer surgery. The goal is to reduce pain and improve recovery after a modified radical mastectomy.
Cairo, Cairo GovernorateAges 18–65 - NCT05912569Recruiting
Test a delayed sentinel lymph node biopsy during mastectomy for DCIS
This trial tests whether doing a “sentinel lymph node biopsy” later (a delayed biopsy) can help assess whether cancer has spread to lymph nodes in people having a mastectomy for DCIS. It may help avoid unnecessary aggressive treatment if lymph nodes look normal.
SeoulAges 20–75
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Common questions
- Are there clinical trials for mastectomy?
- Yes. Clin2 currently lists 117 recruiting mastectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mastectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mastectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.