Clinical trials
Mental Health Conditions clinical trials
Below are recruiting mental health conditions clinical trials, each written for real people, not researchers. We’re tracking 199 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT00025935Recruiting
Brain Function Studies in Youth With Mood and Attention Disorders
This research study examines how the brains of children and teenagers with mood problems (like persistent irritability or depression) or attention difficulties work differently. Researchers use brain scans and tasks to understand these conditions better and track changes as young people grow up.
Bethesda, MarylandAges 7–60 - NCT01132885Recruiting
Brain scans in children with Williams syndrome
This study uses brain testing—often MRI scans—to learn how the brains of children with Williams syndrome are different from typical development. It may help researchers better describe brain patterns and improve future care for people with Williams syndrome.
Bethesda, MarylandAges 5 years+ - NCT02640911Recruiting
Long-term study of certain antipsychines in schizophrenia
This is an observational (non-intervention) study that follows adults with schizophrenia who are taking specific “atypical” antipsychotic medicines long-term. Researchers want to learn about patients’ experiences and outcomes while on these treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT02543983RecruitingPhase 2
Brain scan and ketamine study for suicidal thoughts
This trial studies how ketamine affects the brain in people dealing with suicidal thoughts or an active suicide crisis. It uses questionnaires, consent testing, and brain imaging to look for biological changes that may relate to symptom improvement.
Bethesda, MarylandAges 18–70 - NCT07675538Enrolling by invitation
High intensity training for adults with ADHD
This trial tests whether high intensity exercise helps adults with ADHD. You'll participate in a supervised training program to see if it improves your symptoms.
BergenAges 18 years+ - NCT07417813Recruiting
Lemborexant for insomnia in people with mental health conditions
This study tests if lemborexant, a sleep medication, can help people with both a mental health condition and insomnia. You would take the medicine as prescribed and complete questionnaires over 2 months.
Suzhou, JiangsuAges 18 years+ - NCT07428460Recruiting
Speedy brain stimulation for persistent negative symptoms in schizophrenia
This trial tests if a new, faster form of brain stimulation called accelerated neuromodulation therapy can help reduce negative symptoms (like loss of motivation or social withdrawal) in people with schizophrenia. It aims to see if this treatment can improve daily functioning and quality of life.
Montreal, QuebecAges 18–65 - NCT07559084Recruiting
Brain Stimulation for Schizophrenia Negative Symptoms
This trial tests a newer form of brain stimulation called multi-target TMS (transcranial magnetic stimulation) to help reduce negative symptoms of schizophrenia—like reduced emotion, motivation, and speech—in people whose symptoms aren't fully controlled by medication alone.
Shanghai, Shanghai MunicipalityAges 16–45 - NCT07573839Recruiting
Predicting bipolar disorder relapse using voice and video analysis
This study uses artificial intelligence to analyze speech patterns and facial expressions from people with bipolar disorder to predict who might have a relapse. If successful, it could help doctors identify warning signs earlier and prevent episodes before they happen.
ShanghaiAges 18–64 - NCT07615257Recruiting
Mindfulness and CBT for Psoriasis-Related Emotional Stress
This study tests whether a combination of mindfulness and cognitive behavioral therapy (CBT)—talk-based techniques to manage thoughts and emotions—can help psoriasis patients feel less stressed and more compassionate toward themselves. Participants attend sessions over several weeks to learn these skills.
Rahim Yar Khan, Punjab ProvinceAges 25–75 - NCT07644338Recruiting
Brain Stimulation for Post-Traumatic Stress Disorder
This study tests a new non-invasive brain stimulation technique called temporal interference stimulation to help reduce PTSD symptoms. If you have PTSD that's lasted at least 3 months, this trial may help you or contribute to better treatments for others.
ShanghaiAges 18–50 - NCT07652333Recruiting
Strength training for muscle and mind on obesity medication
This study tests whether strength training can help adults taking new obesity medications (like Wegovy or Ozempic) maintain muscle and improve mental health. You would start the medication after your first study visit.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07284108Enrolling by invitation
Healthy eating for my infant: a program for new moms
This study helps new moms who are feeling stressed or down learn healthy ways to feed their baby. It offers support and education to prevent infant obesity, and may include home grocery delivery.
Cincinnati, OhioAges 2 months–1.8 years - NCT06792175Enrolling by invitation
Using speech to detect mental health conditions
This study uses a computer program to listen to your speech and see if it can help detect mental health or neurodevelopmental conditions. It may help find new ways to diagnose conditions like ADHD, anxiety, depression, and others earlier.
Brookline, MassachusettsAges 13–60 - NCT06667193Enrolling by invitation
Cold water exposure and its effects on health
This study looks at how cold water immersion affects your physical and mental health. It compares people who haven't done cold water exposure before and may help us understand its benefits.
Greeley, ColoradoAges 18–45 - NCT06648928Enrolling by invitation
App for reducing PTSD in Florida 9/11 responders
This study is testing a mobile app called PTSD Coach, along with support from a clinician, to help World Trade Center responders in Florida reduce symptoms of post-traumatic stress. It may be a good fit if you have some PTSD symptoms but not severe alcohol or drug use, and you are not already receiving PTSD treatment.
Miami, FloridaAges Any age - NCT06430853Enrolling by invitation
Pregnancy support study for moms with anxiety or depression
This study tests if a mental health program during pregnancy can help mothers with past or current anxiety or depression. You'll get support and you may feel better and have a healthier pregnancy.
Stanford, CaliforniaAges 18 years+ - NCT05427500Enrolling by invitationPhase 3
Nerve block treatment for PTSD with strong stress-and-alertness symptoms
This Phase 3 study tests whether a procedure called a stellate ganglion block can reduce PTSD symptoms, especially feeling highly “on edge” (hyperarousal). You may join if you have PTSD despite appropriate usual treatments and are able to go through the procedure safely.
Ottawa, OntarioAges 18–69 - NCT07085923Recruiting
Heart health study for people with mental illness
This study tests a program to improve heart health in people with schizophrenia or bipolar disorder who take antipsychotic medication or lithium and have a high body weight. The goal is to help reduce heart disease risk.
OsloAges 25–70 - NCT07278440Recruiting
Exercise program for brain tumor patients and their partners
This study tests if a home exercise program can improve mental and physical health for people with brain tumors and their live-in partners. Both of you will be guided through exercise sessions together over video.
Portland, OregonAges 18 years+ - NCT05956392Recruiting
Personal plan to reduce kids’ screen time for better sleep
This trial tests a personalized program to help children use screens less in order to improve sleep, mood, and brain health. It’s for children who regularly sleep under 8 hours on school nights and spend more than 2 hours per day on media.
SingaporeAges 6–12 - NCT05048680Recruiting
Breathing low-oxygen training to support brain blood flow in seniors
This study tests whether brief “low-oxygen” conditioning can improve blood flow to the brain and overall cerebrovascular (brain blood vessel) health in older adults. It may help people who are generally less active, as long as they have no major medical or safety barriers for the training.
La Tronche, Auvergne-Rhône-AlpesAges 60–80 - NCT05362292RecruitingPhase 4
Treating bladder leakage to support mind and body health
This study tests medicines to reduce “urgency” urine leakage (when you suddenly feel you must go) and to see whether improving bladder control also helps overall mental and physical health. You may be eligible if you have had these symptoms for at least 3 months and can follow the study plan.
Palo Alto, CaliforniaAges 60 years+ - NCT06558825Recruiting
PrEP support for women with trauma history
This study tests a program to help women who have experienced trauma and are at risk for HIV start and stay on PrEP (a daily pill that prevents HIV). It looks at whether mental health treatment can boost PrEP use.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for mental health conditions?
- Yes. Clin2 currently lists 199 recruiting mental health conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.