Clinical trials
Mental Health Conditions clinical trials
Below are recruiting mental health conditions clinical trials, each written for real people, not researchers. We’re tracking 199 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06780917Recruiting
Online cognitive testing for older adults with depression or memory concerns
This study tests whether an online cognitive assessment platform (Creyos) is valid for older adults with major depression or mild cognitive impairment. Participants will complete brain games or puzzles to see how well the online tool measures thinking skills.
Toronto, OntarioAges 60 years+ - NCT06788886Recruiting
Breathing practice for brain and mental health in cancer and other illnesses
This study tests a simple breathing practice to see if it can improve brain health and mental well-being for people with cancer, multiple sclerosis, or their caregivers. You will do light exercises and answer questionnaires, and some participants will also have an MRI brain scan.
Rochester, MinnesotaAges 18–85 - NCT06795581RecruitingPhase 1
Brain imaging study for alcohol use disorder
This study uses a special brain scan (PET) to look at a protein called PDE4B in people with alcohol use disorder. The goal is to better understand how alcohol affects the brain, which may lead to new treatments.
Bethesda, MarylandAges 18–70 - NCT06809166RecruitingPhase 4
Contrave for weight loss in adults with obesity
This study tests whether a weight loss medication called Contrave can help adults with obesity lose weight by changing how their body uses energy and handles food. If you qualify, you will take Contrave and be monitored for several months.
Ottawa, OntarioAges 18–64 - NCT06920628RecruitingPhase 1
Brain scan study for long COVID neurological symptoms
This study uses a special PET scan to look at brain inflammation in people with neurological symptoms after COVID-19. It aims to understand how inflammation might be linked to ongoing problems like brain fog or memory issues.
Bethesda, MarylandAges 18–70 - NCT06923423Recruiting
Cognitive processing therapy for drug use and trauma in prison
This study tests if a type of therapy called cognitive processing therapy (CPT) can help people in prison who have both a drug use problem and trauma-related stress. If you qualify, you would receive CPT and be compared to those getting usual care.
Little Rock, ArkansasAges 18 years+ - NCT06939712Recruiting
Online mental health program for Crohn's patients
This study tests an online program that uses positive psychology to help improve mental health and quality of life in people with Crohn's disease who have mild anxiety or depression. The program is done over the internet, so you can join from home.
Hangzhou, ZhejiangAges 18–75 - NCT06942559Recruiting
Brain stimulation for treatment-resistant OCD
This trial tests a new type of brain stimulation (TMS) that is timed to your brain's natural rhythms, targeting a part of the brain linked to OCD. It may help people whose OCD has not improved with standard treatments.
Toronto, OntarioAges 18–65 - NCT06978894Recruiting
Using speech to detect psychosis relapse early
This study tests whether changes in your speech patterns can help predict a psychotic relapse before it happens. If you're in an early psychosis program, you may help develop a tool that could warn you and your care team early.
London, OntarioAges 16 years+ - NCT06993103RecruitingPhase 4
Pasteurized donor milk for newborns of mothers with diabetes
This trial tests if giving pasteurized donor human milk to newborns of mothers with diabetes can help their health. It compares donor milk to regular baby formula as a supplement when extra feeding is needed soon after birth.
Brisbane, QueenslandAges birth–2 days - NCT07002996Recruiting
Virtual reality memory training for mild cognitive impairment
This study tests whether a special memory training program using virtual reality can improve thinking skills in people with mild cognitive impairment. It may help slow memory loss and keep your mind sharper.
Verdun, QuebecAges 55 years+ - NCT07013578Recruiting
Mental health support trial for IBD patients
This trial tests a mental health program for people with inflammatory bowel disease (IBD) who have mild to moderate anxiety or depression. It aims to see if the program can improve their emotional well-being.
North York, OntarioAges 18–75 - NCT07014852RecruitingEarly Phase 1
Inuit mental health trial with cultural foods and activities
This trial tests whether a program that includes traditional country foods, group conversations, and cultural workshops can improve mental health for Inuit adults. It is designed with Inuit knowledge to make the study feel supportive and relevant.
Arviat, NunavutAges 18–65 - NCT07019493Recruiting
Young stroke recovery study for ages 18 to 55
This study looks at how young adults recover from a stroke. Researchers want to learn more about what helps recovery in the first few months after a stroke.
Heidelberg, VictoriaAges 18–55 - NCT07031544Recruiting
Deep brain stimulation for severe OCD
This study tests whether implanting a small device deep in the brain—like a pacemaker for OCD—can help people whose severe OCD hasn't gotten better with standard medications and therapy.
Guangzhou, GuangdongAges 18–65 - NCT07066631Recruiting
Online mental health support for pregnant and new parents
This trial tests a virtual program to help pregnant people and new parents with depression or anxiety. It provides mental health support through online tools and care coordination.
Toronto, OntarioAges 18 years+ - NCT07073963Recruiting
Online groups for sarcoidosis fatigue
This trial tests whether virtual group sessions can help reduce fatigue related to sarcoidosis. You'll join a supportive online group with others who have similar symptoms.
Cleveland, OhioAges 18 years+ - NCT07113652Recruiting
Brain stimulation for obsessive-compulsive disorder
This trial tests a new type of noninvasive brain stimulation called temporal interference stimulation for people with OCD. It may help reduce symptoms when standard medications have not worked well enough.
Shanghai, Shanghai MunicipalityAges 18–50 - NCT07183748RecruitingPhase 2
Psilocybin microdosing plus therapy for hard-to-treat depression
This trial tests whether taking very small, repeated doses of psilocybin (a substance found in magic mushrooms) along with talk therapy can help people with depression that hasn't gotten better with other treatments. You'll need to stop your current depression medications and avoid drugs or alcohol for the study period.
BeershebaAges 18–65 - NCT07198594Recruiting
Fast brain stimulation for hard-to-treat OCD
This study tests a fast-acting brain stimulation method (accelerated rTMS) for people whose obsessive-compulsive disorder has not improved enough with standard treatments. It aims to help those who still have moderate to severe symptoms despite trying multiple medications.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT07213349RecruitingPhase 2
Daridorexant for Alzheimer's prevention
This study tests whether daridorexant, a medication that helps improve sleep, can prevent Alzheimer's disease. If you have mild memory concerns but not dementia, this trial may help find out if better sleep can protect your brain.
Montreal, QuebecAges 50–90 - NCT07682064Recruiting
Group therapy for emotional disorders in adults
This trial tests a group therapy program for adults with emotional disorders like depression or anxiety. It is designed to help you manage difficult emotions and improve your well-being.
Logroño, La RiojaAges 18–65 - NCT07305688Recruiting
Climate anxiety and suicide risk in young people
This study explores how climate anxiety affects young people who are at risk for suicide. It aims to better understand the link between worries about climate change and suicidal thoughts or behaviors.
LimogesAges 16–24 - NCT01087281Recruiting
Testing how brain “top-down” attention helps visual processing
This study looks at how signals from the brain’s thinking/attention systems affect how we process what we see. It may help researchers understand brain attention after stroke or other focal brain injuries, and compare with healthy volunteers.
Bethesda, MarylandAges 18–100
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Common questions
- Are there clinical trials for mental health conditions?
- Yes. Clin2 currently lists 199 recruiting mental health conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.