Clinical trials
Mental Health (Depression) clinical trials
Below are recruiting mental health (depression) clinical trials, each written for real people, not researchers. We’re tracking 315 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06874790Recruiting
Web-based mental health app study for Latina women
This study tests a web-based app to help Latina women in Los Angeles or Orange County who are feeling anxious or depressed. If you are not currently in therapy or on medication, you may be able to join from home using your smartphone or computer.
Los Angeles, CaliforniaAges 18 years+ - NCT06978452Recruiting
Youth mental health: tracking development and outcomes
This study looks at how young people's mental health develops over time. It compares youth who have already sought help for mental health concerns with those who haven't, to better understand what helps or hinders well-being.
Montreal, QuebecAges 9–25 - NCT07181863Recruiting
Online support for diabetes and mental health
This trial tests a team-based program that combines diabetes care with mental health support. It aims to help you better manage both your diabetes and emotional well-being through remote check-ins and coaching.
Hamilton, OntarioAges 18 years+ - NCT07219264Recruiting
Mental health first aid training for cancer survivors
This study offers a free training program called Mental Health CPR for cancer survivors and their supporters. It is designed to help Latino/Hispanic communities in southern Puerto Rico learn how to provide emotional first aid and mental health support to people affected by cancer.
Ponce, Puerto RicoAges 21–99 - NCT07292610Recruiting
Nut study for young university students
This trial tests whether eating nuts regularly can improve mental health in young adults. If you are a university student aged 18-25, you may be able to join.
Cuenca, CuencaAges 18–24 - NCT07313657Recruiting
Heart health and well-being support study
This study tests a web tool designed to improve mental well-being for adults with heart failure. If you have heart disease or take certain heart medications, you may help shape better care for yourself and others.
Cornwall, OntarioAges 40 years+ - NCT07591363Recruiting
Building Emotional Intelligence Skills for Students and Teachers
This study teaches secondary school students and teachers in Dhaka how to better understand and manage their emotions. It focuses on students who may struggle with emotional awareness and aims to improve their mental health through an emotional intelligence training program.
DhakaAges 12–17 - NCT07561515Enrolling by invitation
Sound Therapy for Anxiety, Stress, and Depression
This study tests whether listening to specially designed sound can help reduce anxiety, stress, or depression. You'll participate for 3 weeks and answer questionnaires about how you feel.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT07375485Enrolling by invitation
Occupational therapy for brain injury recovery at home
This trial explores how occupational therapy can help people with brain injuries stay engaged in daily life. Researchers want to learn from therapists working in home or community settings to improve care.
Denver, ColoradoAges 18 years+ - NCT07064928Enrolling by invitation
Reducing HIV stigma in pregnancy and after birth
This study tests a program to reduce stigma related to HIV among pregnant women and new mothers. You may be eligible if you are living with HIV, are between 24 and 36 weeks pregnant, and plan to stay in the area for at least 6 months after your baby is born.
AccraAges 14 years+ - NCT06997549Recruiting
Review of mental health treatment outcomes
This study looks back at information from a large database of people who received mental health treatments. It aims to understand how well treatments worked and what factors influenced outcomes.
Malvern, PennsylvaniaAges 5–100 - NCT05074901Recruiting
Using a health app in France with virtual support
This trial tests whether a digital health app (with “virtual agents,” like guided prompts/support) can improve people’s health outcomes. You may help the study by using the app and completing its questionnaires.
BordeauxAges 18 years+ - NCT05426057Recruiting
Mental health support for Hispanic teens with caregiver involvement
This study looks at improving mental health in primary care by involving both a teen and an adult caregiver. It may help families who are struggling with communication, depression or anxiety symptoms, or past suicidal thoughts or behaviors.
Miami, FloridaAges 12–16 - NCT04569448RecruitingPhase 3
Brexpiprazole for bipolar depression that won’t improve
This Phase 3 study tests whether brexpiprazole can help treat bipolar depression that has not responded to previous treatments. It compares the study medicine to a placebo (inactive pill) for people with bipolar I or II depression.
Hamilton, OntarioAges 18–75 - NCT06379074Recruiting
Sleep in pregnancy and postpartum mental health
This study looks at how poor sleep during pregnancy might affect stress and mental health after childbirth. It aims to help new mothers by understanding these links.
Bologna, BolognaAges 18 years+ - NCT07136584Recruiting
Support for caregiver wellbeing study
This study is testing a program to support the mental health of parents whose children are being treated for neuromuscular disorders or diabetes at the Royal Children's Hospital. If you are a parent able to fill out a consent form in English without an interpreter, you may be able to join.
Parkville, VictoriaAges Any age - NCT07216638Enrolling by invitation
Better mental health care for kids in primary care
This trial studies how to better integrate mental health care into pediatric primary care clinics across Indiana. It involves surveys, interviews, and looking at patient records to understand and improve care for children.
Indianapolis, IndianaAges 5 years+ - NCT06284551Enrolling by invitation
Youth internet use and mental health study
This study looks at how internet use relates to mental health in young people aged 15 to 24. It compares healthy individuals with those diagnosed with depression, anxiety, PTSD, or adjustment disorder.
TaipeiAges 15–24 - NCT07044154Recruiting
Sun Tai Chi for heart, lung, and mental health in college students
This trial tests whether a gentle Sun-style Tai Chi program can improve your heart and lung fitness as well as your mental well-being if you have mild to moderate stress, anxiety, or depression. It's for university students who are not already very active and who are not taking mental health medicines.
Talca, Maule RegionAges 18–29 - NCT06455397Recruiting
Building emotional awareness and mental health for parents
This trial tests a program called BEAM that helps parents and caregivers of young children (ages 2–5) manage stress, depression, anxiety, or anger. You'll get support from a peer coach through check-ins and learn skills to feel better.
Winnipeg, ManitobaAges 18 years+ - NCT06511908RecruitingPhase 2
Testing a new ketamine-like drug for hard-to-treat depression
This study tests a new experimental drug (2R,6R)-HNK, a chemical related to ketamine, given by IV infusion to see if it can help people with depression that hasn't improved with other treatments. The goal is to find a new option for people who have not found relief from standard antidepressants.
Bethesda, MarylandAges 18–70 - NCT06659315Recruiting
Preventing HIV transmission from mom to baby for depressed mothers in Malawi
This study tests a program to help pregnant women with HIV who also have depression, and their partners, reduce the risk of passing HIV to their babies. The program includes support for mental health and HIV care.
ZombaAges 18 years+ - NCT04685148RecruitingPhase 1/Phase 2
Study of mental health treatment during pregnancy
This trial studies a treatment aimed at improving maternal mental health during pregnancy. It focuses on people who have had depression around pregnancy before, and checks whether the approach is safe and helpful for them.
CopenhagenAges 18–45 - NCT06722287Recruiting
Phone support for family caregivers in Thailand
This study tests a mobile program to support the mental health of family caregivers in Thailand. You participate from home using your phone.
BangkokAges 18–80
Hear when a new Mental Health (Depression) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for mental health (depression)?
- Yes. Clin2 currently lists 315 recruiting mental health (depression) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health (depression) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health (depression) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.