Clinical trials
Mental Health Disorder clinical trials
Below are recruiting mental health disorder clinical trials, each written for real people, not researchers. We’re tracking 522 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06595953RecruitingPhase 2
Music therapy with CBT for child anxiety
This study tests if adding a special music therapy that responds to where your child looks during cognitive behavioral therapy (CBT) can help reduce anxiety better than CBT alone. It is designed for children 8–17 with separation, generalized, or social anxiety.
Bethesda, MarylandAges 8–17 - NCT06881810RecruitingPhase 2
Oxytocin for social skills in schizophrenia
This trial tests if adding oxytocin (a hormone that helps with social bonding) to regular therapy can improve social skills in people with schizophrenia or related disorders. You must have some negative symptoms (like lack of motivation or social withdrawal) and be in treatment at least twice a week.
Mannheim, Baden-WurttembergAges 18–64 - NCT05945277Recruiting
Peer support after a recent hospital stay
This trial tests a “critical time intervention” approach with peer support for people with a psychotic disorder soon after leaving psychiatric inpatient care. It may help by providing practical support during a high-risk period for relapse and distress.
LisbonAges 18–65 - NCT07408934Enrolling by invitation
Group therapy for feeling safer with psychosis
This trial tests a group therapy program called the Feeling Safe Programme for people with psychosis. It aims to help you learn new ways to cope with your symptoms and feel safer. It meets once a week for 75 minutes.
Ottawa, OntarioAges 18 years+ - NCT06163599Recruiting
Telenovela for anxiety in Latinx adults
This trial tests if a telenovela-style video can help reduce anxiety symptoms in Spanish-speaking Latinx adults. You may be eligible if you have mild to moderate anxiety and want to participate from home using your smartphone.
Reno, NevadaAges 18 years+ - NCT06635486Recruiting
Mental health support for Venezuelans in Lima
This study offers mental health support to Venezuelan adults living in Lima who are feeling anxious, depressed, or have experienced trauma. It will check if you have signs of depression, anxiety, or post-traumatic stress and provide help if you do.
LimaAges 18 years+ - NCT06891300RecruitingPhase 2/Phase 3
Ketamine for Suicidal Thoughts in Depression
This study tests if ketamine can help reduce suicidal thoughts in people with major depression. You'll receive ketamine treatment and be monitored closely.
Ottawa, OntarioAges 18–65 - NCT00271622Recruiting
Screening test for child or adult brain and behavior patterns
This study uses a structured check-up to learn about how someone’s thinking, behavior, and development may differ from typical patterns. It involves an interview and possibly medical, nervous-system, and blood or urine tests to understand what kinds of issues might be present.
Bethesda, MarylandAges 1 month+ - NCT06370988Recruiting
Theta-burst stimulation for bipolar depression
This study tests a type of brain stimulation (theta-burst TMS) to see if it helps improve depression in people with bipolar disorder. It might be a good option if you have tried medication but still feel depressed.
Toronto, OntarioAges 18–65 - NCT07408206RecruitingEarly Phase 1
Virtual reality for sleep, dreams, and mental health
This study tests if a virtual reality program can help with mild anxiety by improving sleep and dreaming. You'll wear a headband during sleep to track your dreams.
Evanston, IllinoisAges 18 years+ - NCT06379074Recruiting
Sleep in pregnancy and postpartum mental health
This study looks at how poor sleep during pregnancy might affect stress and mental health after childbirth. It aims to help new mothers by understanding these links.
Bologna, BolognaAges 18 years+ - NCT05491538Recruiting
Work skills training for Veterans living with serious mental illness
This study tests whether a social-skills training program designed for work goals is doable and helpful for Veterans with serious mental illness. It focuses on improving work-related coping and interactions while you receive supported services through the VA.
Minneapolis, MinnesotaAges 18 years+ - NCT07557017Recruiting
Emotional Disorder Treatment Study Using Unified Protocol
This study tests a structured therapy approach called the Unified Protocol, designed to treat multiple emotional disorders (like depression, anxiety, and OCD) with one flexible treatment. Researchers want to see if this approach helps people manage their symptoms over 14 weeks of outpatient therapy.
PragueAges 18 years+ - NCT06959342Recruiting
Brain stimulation to reduce cravings in alcohol use disorder
This trial tests if a gentle brain stimulation technique (tDCS) can help people with alcohol use disorder control their cravings and drinking habits. It is an add-on to your regular treatment.
MannheimAges 18–65 - NCT04582916RecruitingPhase 1
PET scan study of inflammation in major depression
This Phase 1 study uses a PET brain scan to look at inflammation-related activity (cyclooxygenase) in people with major depressive disorder (MDD). It may help researchers better understand how depression is connected to inflammation in the brain.
Bethesda, MarylandAges 18–70 - NCT07484750Recruiting
Mindfulness group therapy for OCD
This trial tests a type of group therapy that combines mindfulness with exposure techniques to help people with obsessive-compulsive disorder (OCD) manage their symptoms. If you have OCD and are between 16 and 55 years old, you may be able to join.
Shanghai, Shanghai MunicipalityAges 16–55 - NCT05142683Recruiting
Test an integrated care plan for teens with depression
This study tests whether a structured, coordinated care pathway helps teens (and their caregivers) manage depression better than usual care. It aims to see if targeted treatment and follow-up improve depression symptoms over time.
Toronto, OntarioAges 13–18 - NCT05851950Recruiting
Group CBT to reduce rumination in psychosis
This trial tests a structured group therapy (rumination-focused CBT) to help reduce repetitive negative thinking (“rumination”) that can worsen symptoms in people with psychosis. It may help you feel less stuck in unhelpful thoughts and improve day-to-day functioning while you continue your usual care.
CopenhagenAges 18–37 - NCT07027839RecruitingPhase 1
Alcohol effects on brain imaging for phosphodiesterase
This study uses PET scans to see how alcohol affects a protein in the brain called PDE4B. It may help explain how alcohol works in the body.
Bethesda, MarylandAges 21–70 - NCT07033780RecruitingPhase 1
Brain stimulation study for depression treatment
This trial tests a new type of brain stimulation called theta-burst stimulation to see if it helps treat depression. It is for people aged 18-50 who are currently experiencing a major depressive episode and are on a stable antidepressant regimen.
Toronto, OntarioAges 18–50 - NCT06290778Enrolling by invitation
Mental health prevention training for fire fighter trainees
This study tests a program where peers teach emotion regulation skills to help prevent mental health issues in new fire fighters. You would be asked to complete surveys and attend training sessions.
Waco, TexasAges 21 years+ - NCT06800833Recruiting
Mango or cookie study for gut, mental, sexual, and skin health
This study is testing whether eating mangoes or low-fat cookies every day for 4 weeks can improve your gut health, and in turn affect your mood, sex life, and skin. If you are generally healthy, not pregnant, and not taking certain medications or supplements, you may be able to join.
San Diego, CaliforniaAges 18–50 - NCT06903819RecruitingPhase 4
Ketamine for pain and mental health after orthopedic injury
This trial tests if ketamine can reduce pain, opioid use, and improve mental health in adults recovering from serious orthopedic injuries. It may help those with high injury severity scores.
Lubbock, TexasAges 18–65 - NCT06973512Recruiting
Brain stimulation for severe addiction
This trial tests a new brain stimulation approach for people with severe addiction that hasn't gotten better with other treatments. It uses deep brain stimulation guided by brain mapping to try to reduce cravings and help you stay abstinent.
Toronto, OntarioAges 25–65
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Common questions
- Are there clinical trials for mental health disorder?
- Yes. Clin2 currently lists 522 recruiting mental health disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.