Clinical trials
Mental Health Disorder clinical trials
Below are recruiting mental health disorder clinical trials, each written for real people, not researchers. We’re tracking 509 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06152705Recruiting
fMRI-Guided vs. Standard Brain Stimulation for Depression
This study compares two types of repetitive transcranial magnetic stimulation (rTMS) to treat depression. One type uses a brain scan (fMRI) to guide the treatment, while the other uses a standard approach. It may help people whose depression hasn't improved with medication.
Ottawa, OntarioAges 18 years+ - NCT04373629Recruiting
Testing how flexible appearance worries may change in BDD
This study looks at whether training can change how people with body appearance worries (including body dysmorphic disorder) perceive faces or the head. It may help researchers understand new ways to reduce distress related to these concerns.
Toronto, OntarioAges 18–40 - NCT07146633Recruiting
Testing an EMDR app for PTSD and substance use
This study tests an app that uses EMDR therapy to help people with both PTSD and substance use problems. EMDR is a type of therapy that uses eye movements or taps to help process traumatic memories. You would use the app at home and avoid starting other new therapies during the study.
Toronto, OntarioAges 18 years+ - NCT07075081RecruitingPhase 2
Cultural healing trial for Ojibwe adults using substances
This trial tests a culturally-based program called Gii'Igoshimong (Sitting With Your First Family) for Ojibwe/Anishinaabe/Chippewa adults who have used substances recently. It aims to support wellness and recovery in a way that respects your heritage.
Duluth, MinnesotaAges 18 years+ - NCT06936930Recruiting
Reproductive and Mental Health in Aplastic Anemia
This study looks at how aplastic anemia affects reproductive and mental health in adults. By understanding these connections, doctors can provide better support for your overall well-being.
Tianjin, Tianjin MunicipalityAges 18–40 - NCT07031661Recruiting
Bipolar disorder risk study for teens and children
This study follows children and teens who may be at higher risk for bipolar disorder to develop a prediction model. It includes three groups: those with a parent who has bipolar disorder, those with atypical depression, and healthy volunteers.
Shanghai, Shanghai MunicipalityAges 6–18 - NCT06675461Enrolling by invitation
Brief talk therapy for suicidal patients with borderline personality disorder
This trial tests a short talk therapy for people with borderline personality disorder who come to the emergency department after hurting themselves or thinking about suicide. The goal is to see if this brief help can ease suicidal thoughts and keep you safer.
Toronto, OntarioAges 16 years+ - NCT07658898Recruiting
Brain stimulation for negative and cognitive symptoms in schizophrenia
This study tests a new type of brain stimulation called temporal interference to see if it can help with negative symptoms (like lack of motivation or emotion) and cognitive symptoms (like trouble with memory or focus) in schizophrenia. It uses a special head device to target a specific brain area.
ShanghaiAges 18–65 - NCT06901739Recruiting
Synbiotic for mental health in obesity
This trial tests if a synbiotic (a mix of probiotics and prebiotics) can improve mental health in people with obesity. It may help if you have obesity and also struggle with anxiety or depression.
Valencia, ValenciaAges 18–65 - NCT06773949Recruiting
Exercise before rTMS for hard-to-treat depression
This trial tests if doing exercise before repetitive transcranial magnetic stimulation (rTMS) can improve depression symptoms in people who haven't gotten better with standard treatments.
Ottawa, OntarioAges 18–75 - NCT06672588Recruiting
Magnetic seizure therapy for schizophrenia
This trial tests a new type of brain stimulation called magnetic seizure therapy (MST) for people with schizophrenia who haven't gotten better with standard medicines. The goal is to see if MST can help reduce symptoms like hallucinations or confusion.
Vancouver, British ColumbiaAges 18 years+ - NCT01327690RecruitingEarly Phase 1
Group therapy for mental health in veterans and families
This early-stage study looks at mental health outcomes for active-duty service members, veterans, and their family members after participating in group therapy sessions. If you can follow instructions and complete consent forms, this trial may help researchers understand how group therapy affects well-being in these communities.
Santa Rosa, CaliforniaAges 18–80 - NCT07573839Recruiting
Predicting bipolar disorder relapse using voice and video analysis
This study uses artificial intelligence to analyze speech patterns and facial expressions from people with bipolar disorder to predict who might have a relapse. If successful, it could help doctors identify warning signs earlier and prevent episodes before they happen.
ShanghaiAges 18–64 - NCT04935619Recruiting
Testing cannabis abstinence effects in depression symptoms
This study looks at how stopping cannabis for a period of time may affect depression symptoms and thinking/memory. You might benefit by getting close monitoring of mood and cognition while researchers compare changes during cannabis abstinence.
Toronto, OntarioAges 18–55 - NCT07292883RecruitingPhase 2
Accelerated TMS for smoking cessation
This trial tests whether a rapid form of brain stimulation (TMS) can help people stop smoking. It is designed for adults who are ready to quit within the next month.
Penetanguishene, OntarioAges 18 years+ - NCT06508450Recruiting
Mental health support for minority young adults
This trial tests a program to help racial and ethnic minority young adults engage with mental health services. It aims to improve access and participation in care.
The Bronx, New YorkAges 18–34 - NCT06780917Recruiting
Online cognitive testing for older adults with depression or memory concerns
This study tests whether an online cognitive assessment platform (Creyos) is valid for older adults with major depression or mild cognitive impairment. Participants will complete brain games or puzzles to see how well the online tool measures thinking skills.
Toronto, OntarioAges 60 years+ - NCT05608434RecruitingPhase 1/Phase 2
Virtual reality ADHD training for kids and teens
This study tests whether a virtual reality (VR) training program can help strengthen attention and focus in children and teens with ADHD. Participants will use a VR headset for training sessions, and the study will compare different groups to see how well the training works.
Bethesda, MarylandAges 8–16 - NCT07613008Recruiting
Mobile app to prevent perinatal depression and anxiety
This study tests a personalized smartphone app designed to help pregnant women and their partners prevent depression and anxiety during pregnancy and after birth. Participants use the app for support and receive check-ins from healthcare providers.
Mairena del Aljarafe, SevillaAges 18 years+ - NCT06456307Recruiting
Stepped care for mood and anxiety during pregnancy
This study tests a step-by-step approach to help pregnant women who are feeling anxious or down. If you are at least 28 weeks pregnant and feeling stressed, worried, or sad, the study will offer you support and check on how you are doing.
NairobiAges 14 years+ - NCT05703685RecruitingPhase 1
Imaging brain inflammation target in depression with PET
This Phase 1 study uses a PET brain scan tracer to see how a specific brain target (PDE4B) is involved in major depressive disorder (MDD). It’s mainly testing whether the imaging approach works and what it shows in people with depression who meet specific safety and medication rules.
Bethesda, MarylandAges 18–70 - NCT05445180Recruiting
Brain scan study of thinking in cannabis users with psychosis
This study uses brain imaging to understand how thinking works in people who use cannabis, comparing those with psychosis to people without psychosis. It may help researchers learn what brain patterns relate to thinking difficulties and how cannabis use fits in.
Montreal, QuebecAges 16–80 - NCT05153369Recruiting
DBT-based care for youth at risk for bipolar disorder
This study tests a structured, “DBT-informed” care program for young people who either have bipolar disorder or are at family risk for it. It may help by offering closer, organized support aimed at preventing or reducing mood problems.
Toronto, OntarioAges 13–23 - NCT04972136Recruiting
Brain stimulation treatment for depression in young adults with autism
This trial studies a noninvasive brain stimulation (rTMS) to help reduce depression symptoms in young adults who have autism. It aims to find out if this treatment can improve mood and daily functioning without requiring recent changes to medications.
Toronto, OntarioAges 16–35
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Common questions
- Are there clinical trials for mental health disorder?
- Yes. Clin2 currently lists 509 recruiting mental health disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.