Clinical trials
Mental Health Disorder clinical trials
Below are recruiting mental health disorder clinical trials, each written for real people, not researchers. We’re tracking 509 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07737821Recruiting
Improv comedy for anxiety and well-being in young Chinese adults
This study tests if attending improv comedy workshops can lower anxiety and boost mental well-being in young Chinese adults in Hong Kong. If you have mild to moderate anxiety and no mental health diagnosis, this low-pressure, fun activity might be a good fit.
Hong KongAges 18–29 - NCT05427500Enrolling by invitationPhase 3
Nerve block treatment for PTSD with strong stress-and-alertness symptoms
This Phase 3 study tests whether a procedure called a stellate ganglion block can reduce PTSD symptoms, especially feeling highly “on edge” (hyperarousal). You may join if you have PTSD despite appropriate usual treatments and are able to go through the procedure safely.
Ottawa, OntarioAges 18–69 - NCT04478838RecruitingPhase 4
Alternate-day antipsychotic dosing for schizophrenia
This trial looks at whether taking an antipsychotic every other day can keep symptoms controlled in adults with schizophrenia or another psychotic disorder. It may help some people avoid daily dosing, but it requires specific medication stability and screening checks.
Toronto, OntarioAges 18 years+ - NCT05515354RecruitingPhase 4
Smoking quit plan matched to your menstrual cycle phase
This Phase 4 study tests a smoking-quit treatment plan timed to your menstrual cycle. It may help you quit smoking and learn how quitting support works for people who menstruate regularly.
Toronto, OntarioAges 18–40 - NCT06717165Recruiting
Brain stimulation with talk therapy for OCD
This study tests if adding a gentle brain stimulation technique (tACS) to cognitive behavioral therapy (CBT) can help reduce OCD symptoms more than CBT alone. It is for adults with OCD who have not completed a full course of CBT before.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT07836348Recruiting
Soteria-style ward versus standard psychiatric ward
This study compares a new type of psychiatric ward that uses a calm, home-like approach (Soteria) with a standard hospital ward. It aims to see if the Soteria-style environment helps men with acute psychosis recover better.
Jerusalem, JerusalemAges 18 years+ - NCT06942858Recruiting
Boosting therapy for anorexia with brain stimulation
This trial tests whether a non-invasive brain stimulation technique called deep transcranial magnetic stimulation (dTMS) can help cognitive-behavioral therapy work better for people with anorexia nervosa. It aims to improve outcomes by targeting brain areas linked to thinking and behavior.
Shanghai, Shanghai MunicipalityAges 18–35 - NCT07609550Recruiting
Early mental health support for pregnant and new mothers
This study tests whether connecting pregnant women and new mothers who have depression or anxiety to mental health care earlier helps them. You'll be part of a larger research program and may receive support through a smartphone app.
Mairena del Aljarafe, SevillaAges 18 years+ - NCT06534047RecruitingPhase 4
Brain stimulation or nicotine patch to help you quit smoking
This study tests whether a brain stimulation treatment called rTMS can help people with psychiatric conditions quit smoking. You will be randomly assigned to get either rTMS or a nicotine patch, and your progress will be tracked to see which treatment works better.
Toronto, OntarioAges 18–70 - NCT07786714Recruiting
Faster brain stimulation for early psychosis risk
This study tests a faster type of brain stimulation, called accelerated neuromodulation therapy, in people who have early signs that could lead to psychosis. The goal is to see if this treatment can help reduce symptoms and improve daily life.
Verdun, QuebecAges 18–34 - NCT07214415RecruitingPhase 2
Hyperbaric oxygen therapy for veterans with brain injury or mental health issues
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and quality of life in veterans with mild traumatic brain injury, PTSD, anxiety, or depression. You must have already tried at least one evidence-based therapy like CBT or EMDR.
Boise, IdahoAges 18–75 - NCT07107906Recruiting
CONNECT program: group telehealth to reduce loneliness in adults 55+
This trial tests a group-based telehealth program called CONNECT, which aims to reduce loneliness, social isolation, and mental health symptoms like anxiety or depression in adults aged 55 and older. You'll join online group sessions instead of in-person programs, making it easier to connect from home.
Winnipeg, ManitobaAges 55 years+ - NCT03380078Enrolling by invitation
Training programs to better support kids with autism
This study tests an organized training plan meant to help mental health programs and schools support children with autism. It involves leaders, therapists/providers, and parents who complete brief surveys and assessments to see what improves care and services.
Sacramento, CaliforniaAges 18 years+ - NCT04539951RecruitingPhase 2
Trial for newly treated obsessive-compulsive disorder
This phase 2 study tests an OCD treatment strategy for people who have not yet had OCD medications or recent OCD therapy. It aims to reduce OCD symptoms, especially for those with moderate-to-severe symptom levels.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT03065335RecruitingPhase 1
Ketamine plus brain imaging to study response in depression
This early-stage study tests how ketamine given once and then repeatedly may change brain signals and related biomarkers in people with major depression. If you’re eligible, the team will use brain imaging and assessments to see who responds and why.
Bethesda, MarylandAges 18–65 - NCT07064629Enrolling by invitation
Virtual reality breathing training for anxiety
This trial tests if using virtual reality with biofeedback to practice relaxation breathing can help people with anxiety disorders. It aims to see if this method is more effective than standard techniques.
Klecany, Czech RepublicAges 18–65 - NCT06086366Recruiting
Brain scan study for depression after COVID-19
This study uses brain scans to understand depression that starts soon after COVID-19. Researchers want to see if there are changes in brain chemistry related to depression, and you may help find new treatment targets.
Toronto, OntarioAges 18–75 - NCT04106713Recruiting
Understanding change across different psychotherapies for anxiety and depression
This study looks at how people change during different types of psychotherapy for anxiety and depression. It aims to understand which treatments work best for different people.
Singapore, SingaporeAges 18–99 - NCT07528261Recruiting
Support Group for Family Caregivers of Stroke Survivors
This study tests whether a support group using acceptance and commitment therapy (a type of counseling that helps people cope with stress) can reduce caregiver burden and distress. You would meet online with other people caring for stroke survivors.
Alameda, CaliforniaAges 40 years+ - NCT06005103Recruiting
Testing a headband that sends brain pulses for depression
This study tests a new headband that sends gentle electrical pulses to the brain (T-PEMF) to lift depression. You might join if you have moderate to severe depression and don't have certain other conditions or implants.
Frederiksberg, Capital RegionAges 18–65 - NCT06798324RecruitingPhase 4
Brain stimulation plus smoking cessation medication for quitting smoking
This trial tests whether combining brain stimulation (tDCS) with a smoking cessation medication (varenicline) helps people quit smoking. You would attend daily visits for two weeks.
Toronto, OntarioAges 18–85 - NCT07001735Recruiting
Talking for Change: Preventing child sexual abuse before it happens
This study tests a program called 'Talking for Change' to help people who are worried they might sexually harm a child. It offers group therapy and support to reduce that risk.
Toronto, OntarioAges 18 years+ - NCT06497920Recruiting
Brain stimulation for motor skills in autistic adults
This trial tests whether a type of brain stimulation called rTMS can improve motor skills (like coordination and movement) in autistic adults. If you have autism and notice challenges with motor function, this study may help.
Toronto, OntarioAges 18–40 - NCT05726045Recruiting
Sleep-based brain training to help you quit smoking
This study tests a way to improve smoking cessation using special sleep-based brain stimulation and memory support. If it works, it may help you stay committed to quitting by strengthening helpful brain learning during sleep.
Mannheim, Baden-WurttembergAges 18–65
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Common questions
- Are there clinical trials for mental health disorder?
- Yes. Clin2 currently lists 509 recruiting mental health disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.