Clinical trials
Mental Health Disorder clinical trials
Below are recruiting mental health disorder clinical trials, each written for real people, not researchers. We’re tracking 509 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07549178Recruiting
Mobile monitoring and care coordination for serious mental illness
This study tests whether combining extra care coordination with tracking data from your smartphone can help improve mental health care and reduce hospital visits. Researchers will use your smartphone to monitor your wellbeing while a care coordinator helps connect you with the support you need.
West Los Angeles, CaliforniaAges 18 years+ - NCT05583747Recruiting
Brain stimulation therapy with guidance for treatment-resistant depression
This study tests a type of brain stimulation (guided iTBS) to improve depression when standard antidepressant treatments haven’t helped. It also checks that the treatment is safe for people who can meet the study and scan safety requirements.
Toronto, OntarioAges 18–65 - NCT06462196Recruiting
Study of Depression, Bipolar Disorder & Suicide Risk
This study looks at how depression, bipolar disorder, and suicide risk naturally change over time. It aims to better understand these conditions so doctors can improve treatments.
Bethesda, MarylandAges 18–120 - NCT03906435Recruiting
Cognitive therapy to prevent problems for very premature NICU babies
This study offers a counseling approach to help prevent “Vulnerable Child Syndrome” in babies born very early and cared for in the NICU. It focuses on support during the early months after birth and compares outcomes for families getting the therapy versus usual support.
Dallas, TexasAges Any age - NCT02639702RecruitingPhase 4
Switching from twice-daily to once-daily clozapine for schizophrenia
This trial tests whether taking clozapine once a day (instead of twice a day) works safely for people with schizophrenia. It may help by simplifying your dosing schedule while closely monitoring your wellbeing.
Toronto, OntarioAges 18 years+ - NCT07757334Recruiting
Group therapy for adults with trauma symptoms in primary care
This study tests a group therapy program for adults who have symptoms related to trauma, such as post-traumatic stress disorder (PTSD) or other stress-related conditions. The therapy is offered in a primary care setting and aims to help participants cope with their symptoms.
Barcelona, BarcelonaAges 18 years+ - NCT07566468Recruiting
Brain rhythm study for youth with ADHD or OCD
This study uses MRI and EEG to understand brain activity related to attention and impulse control in teens with ADHD or OCD. It may help researchers develop better treatments.
Bethesda, MarylandAges 10–17 - NCT06373484Recruiting
Matching treatment for kids with disruptive behavior and their parents
This study aims to find the best treatment approach for children with disruptive behavior by matching them to either group or individual therapy. It could help if your child struggles with behavior like defiance or conduct issues, and you're willing to participate in treatment.
Toronto, OntarioAges 6–12 - NCT07228182Recruiting
Brain stimulation study for gambling disorder
This trial tests a non-invasive brain stimulation method called high-intensity transcranial alternating current stimulation to see if it can reduce gambling urges and behavior in people with gambling disorder.
ShanghaiAges 18–60 - NCT05627492Recruiting
DBT booster sessions for youth at bipolar risk
This study adds short “booster” sessions to Dialectical Behavior Therapy (DBT) for young people who already took part in a prior DBT study, including those with bipolar symptoms or strong family risk. It aims to see if extra DBT support helps mood and coping over time.
Toronto, OntarioAges 14–25 - NCT05153382Recruiting
Dialectical behavior therapy for youth at bipolar risk
This trial tests whether a structured therapy called dialectical behavior therapy (DBT) helps young people with bipolar disorder or at risk for it, especially with self-harm or risky behaviors. It may help by teaching coping skills and improving safety and emotional control.
Toronto, OntarioAges 13–23 - NCT07638267Recruiting
Comparing different intensity levels of yoga for insomnia
This study compares the effects of moderate-intensity versus low-intensity yoga on sleep in adults with insomnia. If you have insomnia and are not already doing much yoga, you may find this study helpful for improving your sleep.
Orlando, FloridaAges 18–40 - NCT06377189Recruiting
Mental health support from a specialist in primary care
This study tests whether adding a psychiatric consultant to your primary care team can help people struggling with mental distress or complex medical issues. If you're already seeing a primary care doctor and need extra mental health support, this might be for you.
Neuchâtel, Canton of NeuchâtelAges 18 years+ - NCT07131215Recruiting
Smart technology for health in early menopause
This trial tests whether a smartphone-based program can help monitor and improve the physical and mental health of women who have recently gone through menopause. It aims to see if technology can support healthy lifestyle changes during this transition.
TainanAges 40–65 - NCT05497115Recruiting
Care model to improve access to mental health after trauma
This trial tests a practical care plan to help people get mental health support after a traumatic injury, especially if screening suggests risk for PTSD or depression. It may help you connect faster to the right kind of treatment after your injury.
Washington, VirginiaAges 16 years+ - NCT04877977Recruiting
Long-Term Follow-Up for People With Mood Disorders
This study follows people with mood disorders over a long time to better understand how symptoms and functioning change. You may be able to join if you already agreed to take part in an earlier mood/anxiety study and you meet basic participation needs.
Bethesda, MarylandAges 18–99 - NCT05245903Recruiting
Test a supplement and track brain changes with wearable sensors
This study tests whether taking nicotinamide riboside (a form of niacin) affects early memory changes in people with mild cognitive impairment (MCI) or mild Alzheimer’s disease (AD). It also uses passive wearable or sensor data (“digital biomarkers”) to measure changes over time.
Belmont, MassachusettsAges 18–89 - NCT06093906Recruiting
Positive processes and transition to health (PATH) study
This study tests a new therapy that may help people recover after a stressful life event. Over about 6 weeks, you'll work with a coach to retrain your brain's patterns and feel more in control again, as well as reconnect with positive activities.
Newark, DelawareAges 18–65 - NCT06795581RecruitingPhase 1
Brain imaging study for alcohol use disorder
This study uses a special brain scan (PET) to look at a protein called PDE4B in people with alcohol use disorder. The goal is to better understand how alcohol affects the brain, which may lead to new treatments.
Bethesda, MarylandAges 18–70 - NCT04798274Recruiting
Brain wiring study in autism using safe hearing tasks
This study looks at how a brain chemical related to calming signals (“GABA”) may affect how people process sounds in autism. The goal is to understand brain function during hearing tasks, which could help guide future treatments.
Bethesda, MarylandAges 11–25 - NCT06641726Recruiting
Global database linking genetics and health records for mental illness
This trial is building a research database that combines genetic information and long-term health data to improve personalized treatment for serious mental illness. You may be eligible if you have been diagnosed or treated for depression, bipolar disorder, schizophrenia, or dementia.
Oxford, OxfordAges 18–110 - NCT07113652Recruiting
Brain stimulation for obsessive-compulsive disorder
This trial tests a new type of noninvasive brain stimulation called temporal interference stimulation for people with OCD. It may help reduce symptoms when standard medications have not worked well enough.
Shanghai, Shanghai MunicipalityAges 18–50 - NCT05973110Recruiting
Virtual reality training to improve thinking in psychosis
This trial tests whether a virtual reality program can help people living with psychosis improve thinking and daily functioning. It may help if your symptoms are currently stable and you can safely use the VR equipment.
Ottawa, OntarioAges 18–60 - NCT00397111Recruiting
MRI brain-scanning study of mood and anxiety in adults
This study uses brain MRI scans and mental tasks to better understand mood and anxiety problems. It may help researchers develop improved MRI methods for studying depression and healthy brain function.
Bethesda, MarylandAges 18–65
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Common questions
- Are there clinical trials for mental health disorder?
- Yes. Clin2 currently lists 509 recruiting mental health disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.