Clinical trials
Metabolism clinical trials
Below are recruiting metabolism clinical trials, each written for real people, not researchers. We’re tracking 1,051 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06044935Recruiting
Nicotinamide riboside for fat burning and metabolism
This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) helps the body burn fat more efficiently during exercise. It may be a good option if you are overweight or have a specific type of diabetes (MODY2) and want to see if a natural supplement can boost your metabolism.
Bethesda, MarylandAges 18–65 - NCT06046651Recruiting
Blood sample collection for lab research
This study collects blood samples from healthy adults to help researchers learn more about how to run lab tests. It involves one visit or at-home collection and might help future medical research.
San Francisco, CaliforniaAges 18 years+ - NCT06041581Enrolling by invitation
Insomnia treatment study for heart health
This study tests whether treating insomnia can help lower your risk for heart disease. If you have trouble sleeping and certain heart risk factors, you may be able to join.
Indianapolis, IndianaAges 40 years+ - NCT06041789RecruitingPhase 2
Does a memory medication affect bone health?
This study looks at whether a common memory medication (called donepezil) can also help keep your bones strong. If you have memory problems and are willing to start this medication, you might be able to join.
Durham, North CarolinaAges 50 years+ - NCT06054516Recruiting
Study of heart metabolism in ischemic heart disease using advanced imaging
This trial uses a special imaging technique (hyperpolarized MRSI) to study metabolism in the heart muscle of people with chronic heart failure caused by ischemic heart disease. It aims to help doctors better understand how the heart uses energy.
Aarhus, Central JutlandAges 18–90 - NCT06032026RecruitingEarly Phase 1
Brain imaging study of tracer distribution in Parkinson's and related conditions
This study uses a special imaging tracer to see how it moves through the body and brain. It may help researchers understand brain changes in Parkinson's disease and related conditions.
Philadelphia, PennsylvaniaAges 40–80 - NCT06003153RecruitingPhase 4
Gene and sugar response study with oral semaglutide
This study looks at how your genes affect your body's response to a diabetes medication called semaglutide. It may help people with slightly high blood sugar (pre-diabetes) understand why some respond better than others.
Boston, MassachusettsAges 18–65 - NCT06023407Enrolling by invitation
Heat therapy for blood sugar and Alzheimer's prevention
This study tests whether regular heat therapy (like sitting in a hot tub) can help improve blood sugar control and lower the risk of Alzheimer's disease in older women who have metabolic problems.
Kansas City, KansasAges 65 years+ - NCT05972564RecruitingPhase 1/Phase 2
SGLT2 inhibitor for metabolic syndrome and heart health
This study tests whether a diabetes medication called an SGLT2 inhibitor can reduce inflammation in body fat and improve blood vessel function in people with metabolic syndrome. It may help prevent heart disease and other complications.
Nashville, TennesseeAges 18 years+ - NCT05973539Recruiting
Study on how different foods change blood lipids
This study tests how your blood fat levels respond to changes in the types of nutrients you eat (carbohydrates, fats, and proteins). It may help researchers understand what dietary patterns best affect heart and metabolism-related blood measures.
OxfordAges 18–65 - NCT05950282Recruiting
Study of insulin sensitivity differences by age and PCOS status
This study looks at how well the body uses insulin (insulin sensitivity) across different ages, sexes, races, body weights, and whether someone has PCOS. It may help researchers understand why insulin function varies and how PCOS could be linked to metabolic health.
Houston, TexasAges 18 years+ - NCT05924295Recruiting
Study how ketone changes in the body with diet and fasting
This study looks at how your body processes “ketones,” which are energy molecules that rise with fasting or low carbohydrate intake. You may be asked to follow strict diet and activity rules before test days so researchers can see what affects ketone metabolism.
Novato, CaliforniaAges 20–70 - NCT05934409Recruiting
Measuring body-fat storage after bariatric surgery
This study looks at how body fat is stored and how that may relate to early improvements in diabetes and heart/liver health after bariatric surgery. It may help researchers understand why some people recover faster and which body changes matter.
Sherbrooke, QuebecAges 18–65 - NCT05903950Recruiting
Air pollution study to help lower blood pressure
This trial tests whether an air-pollution–reduction approach in your home can help lower blood pressure. It focuses on adults with mildly high blood pressure and certain metabolic health markers.
DohaAges 18–60 - NCT05865652Recruiting
7T brain scan study for teens at risk of psychosis
This trial tests how the brain’s cell membranes and energy use look in teens who are at high risk of developing psychosis. It compares them with healthy teens to better understand early brain changes that might help future care.
PoitiersAges 15–25 - NCT04785989Recruiting
Blood and marrow testing to study metabolism in CLL
This study measures how your body’s metabolism works in people with chronic lymphocytic leukemia (CLL). It uses blood tests, and for some people, a bone marrow sample, to better understand what’s happening and potentially guide future treatments.
Madison, WisconsinAges 18 years+ - NCT05831696Recruiting
Compare walking effort with two types of prosthetic knees
This trial studies how much energy it takes to walk when using passive versus powered prosthetic knees. It may help people understand which knee type could make walking feel easier depending on their needs.
Loma Linda, CaliforniaAges 18–75 - NCT05837221Recruiting
Study of the mouth microbiome in oral cancer
This study looks at the types of bacteria in the mouth (the microbiome) in people with oral squamous cell cancer and compares them to people without this cancer. It may help researchers understand what’s different in oral cancer and what could be useful for diagnosis or treatment planning.
Aurora, ColoradoAges 18–100 - NCT05832086RecruitingPhase 2
Fasting-mimicking diet to improve prostate cancer and metabolism
This trial tests whether an intermittent, fasting-like diet can help control metastatic prostate cancer and improve metabolic health in men on hormone therapy. Participants follow a specific diet plan and are monitored by the study team.
Duarte, CaliforniaAges Any age - NCT05799768Enrolling by invitation
Ketogenic diet for rheumatoid arthritis symptoms and inflammation
This study tests whether a very low-carbohydrate, ketogenic diet can improve rheumatoid arthritis (RA). It’s designed for people whose RA treatment is already stable and who are not currently using a keto diet or certain medicines.
Oklahoma City, OklahomaAges 18–65 - NCT03991897Recruiting
Keto diet to treat early arm swelling after lymph node removal
This study tests whether a ketogenic (keto) diet can reduce arm lymphedema (swelling) that started within the last year after lymph node removal. It aims to improve swelling by changing the body’s metabolism.
LeuvenAges 18 years+ - NCT05711758Recruiting
Endoscopic stomach muscle cut for weight loss
This trial tests whether an endoscopic procedure that cuts a stomach outlet muscle can help with weight loss and be safe. You would be screened to make sure you don’t have certain stomach, heart/lung, or pregnancy-related conditions that could make the procedure unsafe.
Boston, MassachusettsAges 18–70 - NCT05722873Recruiting
Study intermittent fasting and its effects on metabolism
This study looks at how intermittent fasting affects your body's “metabolism” (how you use food and manage blood sugar/fats). It may help researchers understand whether this eating pattern changes metabolic health in people at higher risk for type 2 diabetes.
Pittsburgh, PennsylvaniaAges 21–45 - NCT05725967Enrolling by invitation
Endoscopic and bariatric procedures for obesity
This study looks at people who are having obesity-related procedures, including options done with a scope (endoscopic) and revision after prior bariatric surgery. It may help doctors understand outcomes and improve care for people undergoing these treatments.
Boston, MassachusettsAges 18–80
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Common questions
- Are there clinical trials for metabolism?
- Yes. Clin2 currently lists 1,051 recruiting metabolism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.