Clinical trials
Mood clinical trials
Below are recruiting mood clinical trials, each written for real people, not researchers. We’re tracking 144 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06618027Recruiting
Mindfulness program for teens with type 1 diabetes and mood concerns
This trial tests a mindfulness program designed to help teens with type 1 diabetes who are also dealing with feelings of depression or anxiety. The goal is to see if this program can improve their mood and overall well-being.
Aurora, ColoradoAges 13–17 - NCT07685262Recruiting
Bright light therapy for better daytime function in students
This trial tests if morning bright light therapy can help university students feel more awake and function better during the day. You may be eligible if you live in shared student housing and don't have a diagnosed sleep problem.
Hung HomAges 18 years+ - NCT07685925Enrolling by invitation
Health study for 2026 medical interns
This study tracks medical interns during their first year using a smartphone app. It aims to understand how internship affects health.
Ann Arbor, MichiganAges 18 years+ - NCT06709898Recruiting
Returning to work after a stroke
This study looks at how job accommodations can help people return to work after a stroke. It focuses on those who had a stroke within the last year and have some thinking or emotional symptoms.
Helsinki, UusimaaAges 18–68 - NCT06831435Recruiting
Digital therapy for depression study
This study tests if a digital cognitive behavioral therapy program can help treat depression in real-world settings. It is designed for people aged 14 to 60 who have moderate to severe depression symptoms.
Beijing, Beijing MunicipalityAges 14–60 - NCT06839950Recruiting
Sensory profiles and early signs in calm room users
This study looks at the sensory experiences of people newly admitted to a closed psychiatric unit who use a calm room. Researchers want to see if certain early signs or responses to the calm room differ based on a person's unique sensory profile.
Limoges, New AquitaineAges 18–65 - NCT06854367Recruiting
Comparing fast vs. standard brain stimulation for depression in older adults
This study tests if a faster form of brain stimulation (accelerated theta burst stimulation) works as well as the standard version for treating depression in adults 60 and older. It may help those who haven't gotten relief from antidepressant medications.
Toronto, OntarioAges 60 years+ - NCT06860165Recruiting
Mood tracking app study for adults with depression
This study tests a smartphone app (EmoDTx) that monitors mood in people with unipolar depression. It aims to see if the app can provide helpful digital measurements of your mood.
Changé, FranceAges 18 years+ - NCT06870006Recruiting
Heart monitoring for kids starting psychiatric drugs
This study is for children and teens in a hospital psychiatric ward who are starting a new medicine that might affect their heart's rhythm. It will check your heart with an ECG (electrocardiogram) to make sure it stays safe.
Troina, EnnaAges Up to 18 years - NCT06875986Recruiting
Study of REXULTI for agitation in Alzheimer's disease
This trial is studying how a medication called REXULTI works in patients with Alzheimer's disease who have symptoms like excessive activity, aggression, or mood swings. It aims to see if the drug helps manage these behaviors.
Osaka, OsakaAges 15 years+ - NCT06897670Recruiting
Brain blood flow patterns in mood and memory disorders
This study uses a headband with light sensors (fNIRS) to measure blood flow in the brain while you do thinking tasks. It aims to understand differences in brain activity for people with depression, bipolar disorder, or mild memory loss.
Rochester, MinnesotaAges 18 years+ - NCT06911723Recruiting
Testing a mood-changing activity for people with psychosis and healthy volunteers
This study tests whether a mood-changing activity works for people with psychotic disorders (like schizophrenia) and healthy volunteers. It aims to see if it's acceptable and helpful.
Birmingham, AlabamaAges 18–65 - NCT06929442Recruiting
Prevention program for young adults with unusual experiences
This study tests a program to help young adults who have had unusual thoughts or experiences (like feeling people are talking about them or that things have hidden meanings) learn ways to cope and feel better. The goal is to prevent these experiences from turning into bigger problems.
Charlestown, MassachusettsAges 18–30 - NCT06981195RecruitingPhase 2
Testing lemborexant for insomnia in people on buprenorphine
This study tests if the sleep medication lemborexant can help people with opioid use disorder who also have chronic insomnia. Participants must already be taking buprenorphine (Suboxone) for at least 4 weeks. The goal is to see if better sleep improves mood and reduces opioid use.
Richmond, VirginiaAges 18 years+ - NCT07027319Recruiting
Triple P training for parents of children with autism
This study tests Triple P—a parenting program—to see if it helps reduce repetitive behaviors in children with autism and improves parents' mood and burnout. It is for Turkish-speaking parents of children with autism aged 0–12.
Istanbul, ÜsküdarAges birth–12 years - NCT07033052Recruiting
Art therapy for anxiety and depression in teens
This trial tests whether art-based activities can help children and teens aged 8 to 17 who feel anxious or depressed. Parents must agree to let their child join.
Cleveland, OhioAges 8–17 - NCT07045792Recruiting
Body awareness therapy for stressed young adults
This trial tests if body awareness therapy can help reduce stress, improve balance, sleep, and mood in young adults who are experiencing high stress. If you are between 20 and 30 years old and feel very stressed, this study may be a good fit.
Hatay, AntakyaAges 20–30 - NCT07058324Recruiting
Can chicory root prebiotic improve mood and stress?
This trial tests whether a prebiotic from chicory root can help healthy adults with mild to moderate stress and anxiety feel calmer and handle stress better. You'll take the prebiotic or a placebo for a period and complete mood and stress tests.
Trier, Rhineland-PalatinateAges 18–70 - NCT07071181Recruiting
Milk-based drinks for better sleep and health
This trial tests whether drinking a milk-based drink every day for four weeks can improve gut health, sleep quality, and heart health. It may be a good option if you have trouble sleeping and are overweight.
Leeds, West YorkshireAges 40–70 - NCT07072728RecruitingPhase 2
Psilocybin therapy for anxiety in cancer patients
This trial tests whether psilocybin (a psychedelic drug given with talk therapy) can help people with cancer who have adjustment disorder—a condition where a cancer diagnosis causes severe anxiety or stress. It focuses on reducing anxiety and improving emotional well-being.
Abbotsford, VictoriaAges 18–80 - NCT07079930RecruitingPhase 1
Study on psilocybin and D-serine safety in healthy volunteers
This trial tests whether a combination of psilocybin and D-serine is safe and affects mood and thinking. It's for healthy people who want to help research on psychedelics.
JerusalemAges 25–60 - NCT07087353Recruiting
Remote monitoring for moderate to severe depression
This study tests whether checking in with a mental health team remotely (using your phone) can help people with moderate to severe depression feel better. It’s designed for people who are already getting treatment and want extra support from home.
BesançonAges 18 years+ - NCT07088939Recruiting
Online skills course for depression and anxiety
This trial tests an online course that teaches skills to manage emotions. It is for people in Ontario with mild depression or anxiety who are not currently in therapy.
Windsor, OntarioAges 18 years+ - NCT07089238Recruiting
Citicoline for mood in healthy adults
This study tests whether a supplement called citicoline can improve mood in healthy adults who have some mild mood disturbance. It is designed to see if taking citicoline leads to a better mood.
Canfield, OhioAges 21–65
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Common questions
- Are there clinical trials for mood?
- Yes. Clin2 currently lists 144 recruiting mood studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mood trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mood trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.