Clinical trials
Mood clinical trials
Below are recruiting mood clinical trials, each written for real people, not researchers. We’re tracking 145 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07220447RecruitingEarly Phase 1
L-Theanine for relaxation and mood in cancer survivors
This trial tests whether a natural supplement called L-theanine, found in green tea, can help cancer survivors feel more relaxed and improve their mood. You may qualify if you have finished cancer treatment, have been in surveillance for at least 6 months, and feel anxious.
Duarte, CaliforniaAges 18 years+ - NCT07217925Recruiting
Neurofeedback for people with OCD and PTSD symptoms
This study tests whether a brain training technique called neurofeedback can improve well-being in people who have both OCD and post-traumatic stress symptoms. It is for adults on a therapy waiting list who do not have other serious untreated conditions.
Detroit, MichiganAges 18–90 - NCT07212075Recruiting
Digital twin study for mental health in diabetes
This study uses digital twins—a virtual model of your health—to track how your mental health changes with diabetes. It aims to find patterns that could help personalize mental health care.
Bad Mergentheim, Baden-WurttembergAges 18–80 - NCT07210684Recruiting
Dihydroberberine for blood sugar, appetite, and mood in prediabetes
This study tests a supplement called dihydroberberine (DHB) to see if it helps improve blood sugar control, appetite, and mood in adults with prediabetes. You will wear a small sensor to track your blood sugar and use a phone app to record what you eat.
Addison, IllinoisAges 35–65 - NCT07201909Recruiting
Can a special fiber improve stress and mood?
This study tests whether a prebiotic fiber blend can help reduce stress, improve mood, and ease anxiety in adults with mild to severe stress levels. You'll take the fiber daily and report how you feel over several weeks.
LondonAges 18–50 - NCT07188506Recruiting
Youth suicide risk: reducing risk factors in young people
This study looks at suicide risk factors in young people with mood disorders (like depression or bipolar disorder) and tests ways to reduce those risks. It may help if you are between 18 and 25, have a mood disorder, and can undergo an MRI.
Roma, RMAges 18–25 - NCT07180537Recruiting
Health course for joint and mood conditions
This study tests an online health course that helps improve diet and self-care to support cell health and wellbeing. It is for people with certain rheumatological conditions like rheumatoid arthritis, lupus, or psoriatic arthritis, who also have mood concerns.
Iowa City, IowaAges 18–100 - NCT07155707Recruiting
Virtual therapy platform for mood and anxiety disorders
This trial tests a virtual therapy platform called Teleo for people with mood or anxiety disorders. It looks at how well patients engage with online therapy and whether it helps their symptoms.
Monterey, CaliforniaAges 5–14 - NCT07151846Enrolling by invitation
Using phone data to predict depression
This study uses your smartphone and a Fitbit to track mood patterns and see if they can predict depression. You may join as someone with a mood disorder, as a healthy volunteer, or as someone at higher risk for mood problems.
Seoul, Seongbuk-guAges 19–75 - NCT07120711Recruiting
Sleep apnea, thinking, and mood study for kids and adults
This study looks at how sleep apnea affects thinking and mood by checking certain proteins in the body. They want to see if these proteins can help predict or explain changes in memory, focus, or emotions.
ShanghaiAges 5 years+ - NCT02443636Recruiting
Join a depression and mental health research registry in Atlantic Canada
This trial is a “registry,” meaning you can share your health information to help researchers study depression and other mental health needs in Atlantic Canada. Being part of the registry may help researchers understand patterns and improve future support and treatments.
Halifax, Nova ScotiaAges Any age - NCT07101796Recruiting
Mood and personality in sleep apnea treatment
This study looks at how mood and personality traits affect treatment adherence in people with suspected or confirmed sleep apnea. It may help tailor support for better treatment outcomes.
Beijing, Beijing MunicipalityAges 18–70 - NCT07089238Recruiting
Citicoline for mood in healthy adults
This study tests whether a supplement called citicoline can improve mood in healthy adults who have some mild mood disturbance. It is designed to see if taking citicoline leads to a better mood.
Canfield, OhioAges 21–65 - NCT07087353Recruiting
Remote monitoring for moderate to severe depression
This study tests whether checking in with a mental health team remotely (using your phone) can help people with moderate to severe depression feel better. It’s designed for people who are already getting treatment and want extra support from home.
BesançonAges 18 years+ - NCT07092605Enrolling by invitationEarly Phase 1
Microdosed semaglutide for longer, healthier life
This trial tests whether a very low ('micro') dose of semaglutide can improve health, quality of life, and how long you live well. It's for people who are interested in the drug's general health benefits but not specifically for weight loss.
Ann Arbor, MichiganAges 18–65 - NCT07088939Recruiting
Online skills course for depression and anxiety
This trial tests an online course that teaches skills to manage emotions. It is for people in Ontario with mild depression or anxiety who are not currently in therapy.
Windsor, OntarioAges 18 years+ - NCT07079930RecruitingPhase 1
Study on psilocybin and D-serine safety in healthy volunteers
This trial tests whether a combination of psilocybin and D-serine is safe and affects mood and thinking. It's for healthy people who want to help research on psychedelics.
JerusalemAges 25–60 - NCT07072728RecruitingPhase 2
Psilocybin therapy for anxiety in cancer patients
This trial tests whether psilocybin (a psychedelic drug given with talk therapy) can help people with cancer who have adjustment disorder—a condition where a cancer diagnosis causes severe anxiety or stress. It focuses on reducing anxiety and improving emotional well-being.
Abbotsford, VictoriaAges 18–80 - NCT07071181Recruiting
Milk-based drinks for better sleep and health
This trial tests whether drinking a milk-based drink every day for four weeks can improve gut health, sleep quality, and heart health. It may be a good option if you have trouble sleeping and are overweight.
Leeds, West YorkshireAges 40–70 - NCT07058324Recruiting
Can chicory root prebiotic improve mood and stress?
This trial tests whether a prebiotic from chicory root can help healthy adults with mild to moderate stress and anxiety feel calmer and handle stress better. You'll take the prebiotic or a placebo for a period and complete mood and stress tests.
Trier, Rhineland-PalatinateAges 18–70 - NCT07052357Enrolling by invitation
Intern health study 2025
This study looks at how medical interns' health changes during their first year of training. You wear a wrist device and answer questions on your phone to help researchers understand stress, sleep, and well-being.
Ann Arbor, MichiganAges 18 years+ - NCT07045792Recruiting
Body awareness therapy for stressed young adults
This trial tests if body awareness therapy can help reduce stress, improve balance, sleep, and mood in young adults who are experiencing high stress. If you are between 20 and 30 years old and feel very stressed, this study may be a good fit.
Hatay, AntakyaAges 20–30 - NCT07027319Recruiting
Triple P training for parents of children with autism
This study tests Triple P—a parenting program—to see if it helps reduce repetitive behaviors in children with autism and improves parents' mood and burnout. It is for Turkish-speaking parents of children with autism aged 0–12.
Istanbul, ÜsküdarAges birth–12 years - NCT07033052Recruiting
Art therapy for anxiety and depression in teens
This trial tests whether art-based activities can help children and teens aged 8 to 17 who feel anxious or depressed. Parents must agree to let their child join.
Cleveland, OhioAges 8–17
Hear when a new Mood trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for mood?
- Yes. Clin2 currently lists 145 recruiting mood studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mood trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mood trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.