Clinical trials
Mood clinical trials
Below are recruiting mood clinical trials, each written for real people, not researchers. We’re tracking 144 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07101796Recruiting
Mood and personality in sleep apnea treatment
This study looks at how mood and personality traits affect treatment adherence in people with suspected or confirmed sleep apnea. It may help tailor support for better treatment outcomes.
Beijing, Beijing MunicipalityAges 18–70 - NCT07120711Recruiting
Sleep apnea, thinking, and mood study for kids and adults
This study looks at how sleep apnea affects thinking and mood by checking certain proteins in the body. They want to see if these proteins can help predict or explain changes in memory, focus, or emotions.
ShanghaiAges 5 years+ - NCT07201909Recruiting
Can a special fiber improve stress and mood?
This study tests whether a prebiotic fiber blend can help reduce stress, improve mood, and ease anxiety in adults with mild to severe stress levels. You'll take the fiber daily and report how you feel over several weeks.
LondonAges 18–50 - NCT07210684Recruiting
Dihydroberberine for blood sugar, appetite, and mood in prediabetes
This study tests a supplement called dihydroberberine (DHB) to see if it helps improve blood sugar control, appetite, and mood in adults with prediabetes. You will wear a small sensor to track your blood sugar and use a phone app to record what you eat.
Addison, IllinoisAges 35–65 - NCT07212075Recruiting
Digital twin study for mental health in diabetes
This study uses digital twins—a virtual model of your health—to track how your mental health changes with diabetes. It aims to find patterns that could help personalize mental health care.
Bad Mergentheim, Baden-WurttembergAges 18–80 - NCT07246044Recruiting
Brain stimulation for teens with bipolar depression targeting S1
This trial tests a non-invasive brain stimulation technique (HD-tDCS) to see if it can help teens with bipolar disorder who are currently in a depressive episode. It aims to find a new treatment option for adolescent bipolar depression.
Nanjing, JiangsuAges 12–18 - NCT07362511Recruiting
Imagery rescripting for depression in primary care
This study tests a type of talk therapy called 'imagery rescripting' for people with depression in primary care. In this approach, you learn to change painful mental images into more helpful ones, which may reduce depressive feelings.
Amsterdam, North HollandAges 18–70 - NCT07364929Recruiting
Glaucoma and its effects on sleep, mood, and thinking
This study looks at how glaucoma affects your body's natural light sensing, which can impact sleep, alertness, mood, and memory. Researchers compare people with glaucoma to healthy volunteers to understand these effects better.
SingaporeAges 45–75 - NCT07389473Recruiting
Studying eye movements in long-term psychiatric medication use (Gaize device)
This trial uses a special device (Gaize) to track how your eyes move while you take psychiatric medication. It aims to see how long-term medication affects eye patterns, which could help doctors better understand treatment responses.
Philadelphia, PennsylvaniaAges 18–65 - NCT00025935Recruiting
Brain Function Studies in Youth With Mood and Attention Disorders
This research study examines how the brains of children and teenagers with mood problems (like persistent irritability or depression) or attention difficulties work differently. Researchers use brain scans and tasks to understand these conditions better and track changes as young people grow up.
Bethesda, MarylandAges 7–60 - NCT02443636Recruiting
Join a depression and mental health research registry in Atlantic Canada
This trial is a “registry,” meaning you can share your health information to help researchers study depression and other mental health needs in Atlantic Canada. Being part of the registry may help researchers understand patterns and improve future support and treatments.
Halifax, Nova ScotiaAges Any age - NCT07676110Recruiting
Music and nature visuals for emotional well-being
This study tests if listening to enhanced music and watching natural visuals can improve your emotional health. You'll use your own headphones and a smartphone or tablet to take part.
Fort Collins, ColoradoAges 13 years+ - NCT07404085Recruiting
Cognitive training with medication for mood disorders
This trial tests if a medication can boost the effects of cognitive training in people with bipolar disorder or recurrent depression who have memory or thinking problems. It aims to improve daily functioning.
Frederiksberg, Capital Region of DenmarkAges 40–75 - NCT07155707Recruiting
Virtual therapy platform for mood and anxiety disorders
This trial tests a virtual therapy platform called Teleo for people with mood or anxiety disorders. It looks at how well patients engage with online therapy and whether it helps their symptoms.
Monterey, CaliforniaAges 5–14 - NCT07528014Recruiting
Tracking Depression Treatment Outcomes Over Time
This study follows adults receiving depression treatment (esketamine, TMS, or SAINT) to understand how these therapies work and their effects over time. Researchers will assess mood, functioning, and other factors to help improve future treatment.
La Jolla, CaliforniaAges 18 years+ - NCT07572526Recruiting
Brain Stimulation to Improve Sleep and Mood in Depression
This study tests a non-invasive brain stimulation technique called tDCS (transcranial direct current stimulation) to see if improving sleep can help reduce depression symptoms. You'll do short stimulation sessions at home and track your sleep and mood.
New York, New YorkAges 18–65 - NCT07626944Recruiting
Music and Sound Therapy for Dementia Behaviors
This study tests whether special music and sound patterns can help reduce difficult behaviors and improve mood in people with dementia living in assisted care. Researchers will play these sounds to you and track any changes in how you feel and behave.
Denver, ColoradoAges 55–95 - NCT07600840Enrolling by invitation
Smart Watch and App for Understanding and Treating Sleep Problems
This study tests a combination of a wearable smart watch, brain-wave monitor (EEG), and smartphone app designed to help understand your sleep problems and emotions. The goal is to develop a digital tool that tracks your sleep patterns and mood to improve insomnia treatment.
Taipei, TaipeiAges 18–64 - NCT07495189Enrolling by invitation
Mood, sleep, and brain study
This trial looks at how mood problems and sleep issues affect each other. It compares people with and without these conditions to understand the connection.
Jinan, ShandongAges 18–80 - NCT07151846Enrolling by invitation
Using phone data to predict depression
This study uses your smartphone and a Fitbit to track mood patterns and see if they can predict depression. You may join as someone with a mood disorder, as a healthy volunteer, or as someone at higher risk for mood problems.
Seoul, Seongbuk-guAges 19–75 - NCT07092605Enrolling by invitationEarly Phase 1
Microdosed semaglutide for longer, healthier life
This trial tests whether a very low ('micro') dose of semaglutide can improve health, quality of life, and how long you live well. It's for people who are interested in the drug's general health benefits but not specifically for weight loss.
Ann Arbor, MichiganAges 18–65 - NCT06924268Enrolling by invitation
Art therapy for mood and symptoms in palliative care
This trial tests whether a single art therapy session can improve mood and reduce symptom burden for patients in a palliative care unit. It aims to see if creative expression can help you feel better emotionally and physically.
Halifax, Nova ScotiaAges 18 years+ - NCT06642454Enrolling by invitation
Breathing-guided nerve stimulation for Parkinson's disease
This study tests a type of nerve stimulation (vagus nerve) for Parkinson's disease. It compares a method that uses your breathing cycle to deliver stimulation versus standard stimulation. The goal is to see which works better for movement and non-movement symptoms.
Hefei, AnhuiAges 40–80 - NCT03736538Enrolling by invitationPhase 1
Nitrous oxide for suicidal thoughts in depression
This Phase 1 study tests whether breathing nitrous oxide can safely reduce suicidal thoughts in adults with major depression. It may help people whose depression is causing moderate to severe suicidal thinking, by studying a fast-acting treatment approach.
St Louis, MissouriAges 18–65
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Common questions
- Are there clinical trials for mood?
- Yes. Clin2 currently lists 144 recruiting mood studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mood trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mood trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.