Clinical trials
Musculoskeletal Diseases or Conditions clinical trials
Below are recruiting musculoskeletal diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,023 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05751967RecruitingPhase 3
Fenofibrate plus ursodeoxycholic acid for primary biliary cholangitis
This trial tests whether adding fenofibrate to ursodeoxycholic acid (UDCA) can improve liver test results in people with primary biliary cholangitis (PBC) who did not respond enough to UDCA alone. It aims to see if the combination works better and is safe for adults with persistent, abnormal liver markers.
Lanzhou, GansuAges 18–75 - NCT05766761Recruiting
Support to reduce alcohol during pregnancy
This study aims to help reduce alcohol use in pregnancy by offering support or testing an approach for people who’ve had alcohol recently. It may help you lower the risk to your pregnancy by focusing on alcohol exposure.
Houston, TexasAges 18 years+ - NCT05748613Recruiting
Anxiety-focused skills training for people with Alzheimer’s
This study tests a treatment aimed at reducing anxiety in people who have Alzheimer’s disease or related memory problems. It also involves a support partner, and the goal is to see whether the program can lower anxiety and stress day-to-day.
Tallahassee, FloridaAges 60 years+ - NCT05748197RecruitingPhase 1
Study of ADCLEC.syn1 for relapsed or resistant AML
This Phase 1 study tests ADCLEC.syn1, a new treatment made from a patient’s immune cells, in adults with relapsed or refractory acute myeloid leukemia (AML). The goal is to see how safe it is and how well it may work, especially after standard treatments have not helped.
Basking Ridge, New JerseyAges 18 years+ - NCT05749822RecruitingPhase 2/Phase 3
Fenofibrate for primary biliary cholangitis with stable cirrhosis
This trial studies whether fenofibrate (a cholesterol medicine) can improve outcomes in people with primary biliary cholangitis (PBC) who already take ursodeoxycholic acid (UDCA) but still have abnormal liver blood tests. It specifically looks at people with “compensated” (stable) cirrhosis—meaning the liver disease is present but not causing severe complications right now.
Beijing, Beijing MunicipalityAges 18–75 - NCT05731141Recruiting
Study of lymphatic birthmarks and related genetic conditions
This study follows people who have lymphatic anomalies (lymphatic birthmarks) and sometimes related vascular or genetic conditions. It aims to better understand how these problems develop and what genetic causes may be involved.
Bethesda, MarylandAges 1 day–100 years - NCT04908696Recruiting
Treatment study for laryngeal and hypopharyngeal cancers
This trial tests treatment approaches for people with cancers of the voice box (larynx) or lower throat (hypopharynx). It may help by finding which treatment strategy works best for different tumor locations and cancer stages.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT04871607RecruitingPhase 2
Yttrium antibody plus chemotherapy for hard-to-treat Hodgkin lymphoma
This trial studies a targeted antibody therapy with yttrium, combined with intensive chemotherapy, for adults whose Hodgkin lymphoma did not respond well or came back. It may help by delivering cancer-killing radiation directly to lymphoma cells and preparing the body for treatment after transplant conditioning.
Duarte, CaliforniaAges 18 years+ - NCT05743582Recruiting
Studying natural immunity in COPD and in healthy adults
This study looks at how the body’s “innate” (first-line) immune system works in people with COPD compared with healthy volunteers. It may help researchers understand COPD inflammation and how immune responses could be targeted in the future.
EdinburghAges 18–77 - NCT05721911Recruiting
Study using brain-cell tests to better understand Parkinson’s risk
This study collects blood and related samples to create a “biobank” and uses lab tests to study genetic risk in Parkinson’s disease and idiopathic REM sleep behavior disorder (RBD). It may help researchers understand why symptoms develop and improve future prevention or treatment approaches.
Milan, ItalyAges 18 years+ - NCT05711758Recruiting
Endoscopic stomach muscle cut for weight loss
This trial tests whether an endoscopic procedure that cuts a stomach outlet muscle can help with weight loss and be safe. You would be screened to make sure you don’t have certain stomach, heart/lung, or pregnancy-related conditions that could make the procedure unsafe.
Boston, MassachusettsAges 18–70 - NCT05725928Recruiting
Walking-support program for older hospitalized patients
This study tests whether extra help and guidance to walk while you’re in the hospital can improve health and recovery. It’s for older adults who can safely do some walking after being admitted for a medical problem.
Springfield, MassachusettsAges 65 years+ - NCT05715814RecruitingPhase 3
Test diabetes-pill type medicine on kidney dialysis safety
This Phase 3 trial studies the safety of an SGLT2 inhibitor (a diabetes medication that can affect kidney fluid handling) in people on peritoneal dialysis. The goal is to see how the treatment works in your type of dialysis and whether it causes any problems.
Toronto, OntarioAges 18 years+ - NCT05372263Recruiting
Tracking safety of pulmonary hypertension medicines by computer follow-up
This study checks how safe pulmonary hypertension–targeted medicines (and some calcium-blocking medicines) are over time. It uses a computer system to follow you after diagnosis, looking at outcomes and side effects.
Beijing, Beijing MunicipalityAges 3 months–85 years - NCT05698745Recruiting
Study of the immune features soon after bowel disease starts
This study looks at immune system changes in people around the time inflammatory bowel disease (IBD) is first diagnosed, and compares different groups (new, very recent, or not found on scope). It may help researchers understand what the immune system looks like early in IBD and later in people who don’t show it on colonoscopy.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT05703919RecruitingPhase 4
Compare standard vs targeted oxygen for COPD flare-ups
This trial tests whether giving oxygen in a standard way or a more targeted way helps people who are having a COPD flare-up before they reach the hospital. It may help reduce oxygen-related harms while still treating low oxygen during emergency care.
Aarhus NAges 40 years+ - NCT05674539Enrolling by invitationPhase 3
Less intense transplant regimen for AML or MDS patients
This trial tests whether a less intense chemotherapy and transplant plan can work for adults with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) who are getting a stem cell transplant. It may help reduce transplant-related harm, especially in people considered higher risk due to age or other health factors.
Wuhan, HubeiAges 18 years+ - NCT05701059Recruiting
Tests different artificial discs for neck nerve and spinal cord problems
This trial compares two types of artificial disc implants used for certain neck problems. It may help people who have tried non-surgical treatments but still have ongoing nerve symptoms or spinal cord issues from a damaged disc in the neck.
Los Angeles, CaliforniaAges 18–60 - NCT05684562Recruiting
Lung function and exercise capacity in Fontan patients
This study looks at how well the lungs and heart work together during exercise in people who have had the Fontan operation. The goal is to understand how lung function affects overall fitness, which can help improve care for Fontan patients.
AnkaraAges 8–55 - NCT02872532Recruiting
Freezing testicle tissue in children before cancer treatment
This trial studies how doctors collect and freeze a small piece of testicle tissue from boys to protect future fertility before treatments like chemotherapy or radiation. It may help families preserve options for having children later if testicular function is permanently affected.
Rochester, MinnesotaAges birth–17 years - NCT05671757RecruitingPhase 1/Phase 2
Daratumumab for primary antiphospholipid syndrome
This early-phase study tests daratumumab, an immune-targeting drug, for people with primary antiphospholipid syndrome (APS). It aims to see whether it can reduce APS activity and improve outcomes while you continue your usual blood-thinning treatment.
Baltimore, MarylandAges 18–65 - NCT05652478RecruitingPhase 2
How HIV prevention drugs affect metabolism in healthy people
This study tests how certain HIV prevention drugs affect the body's metabolism (how it uses energy) in healthy people. It aims to understand side effects before these drugs are used more widely, which could help make future treatments safer.
Bethesda, MarylandAges 18–55 - NCT05656365Recruiting
Study of genes and immunity in PFAPA and other tonsil problems
This study looks at genetic markers and immune system patterns in people with PFAPA (periodic fevers with mouth sores and throat/neck gland symptoms) or similar tonsil problems. It may help researchers understand why these conditions happen and how they might be better diagnosed or treated.
Washington D.C., District of ColumbiaAges 1 month–99 years - NCT05663502Recruiting
Donate blood and tissue samples for HIV-related cancer research
This study collects blood and tissue samples to help researchers learn more about cancers related to HIV/AIDS. You may be able to join if you’re 18+ and have HIV and a cancer diagnosis, or (if HIV-negative) a certain cancer that is closely linked to AIDS-related cancers.
La Jolla, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for musculoskeletal diseases or conditions?
- Yes. Clin2 currently lists 4,023 recruiting musculoskeletal diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.