Clinical trials
Neoplasms clinical trials
Below are recruiting neoplasms clinical trials, each written for real people, not researchers. We’re tracking 1,691 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04654208Recruiting
Study people who took palbociclib prescriptions
This study uses prescription records to learn about real-world use of palbociclib (a cancer medicine). You may be included if you’re an adult and have filled at least one palbociclib prescription.
SollentunaAges 18 years+ - NCT04654975Recruiting
Metastatic brain tumors after esophagus surgery study
This study looks at people who had esophageal cancer surgery and later developed brain metastases. It may help doctors better understand who benefits from treatment planning after the original cancer surgery.
Houston, TexasAges Any age - NCT04669873Recruiting
Partial breast radiation vs whole breast radiation after lumpectomy
This trial studies whether treating only part of the breast with radiation works as well as treating the whole breast in people with early breast cancer after lumpectomy. It may help reduce radiation exposure to healthy tissue, while still controlling the cancer.
São Paulo, São PauloAges 50–90 - NCT04678648RecruitingPhase 1
Testing RSC-1255 in advanced cancers with RAS changes
This early study (Phase 1) tests a new drug, RSC-1255, in people with advanced or metastatic cancers that have RAS mutations. It’s mainly focused on whether the treatment can be given safely and at what dose, and to see if it may shrink tumors.
Los Angeles, CaliforniaAges 18 years+ - NCT04681690Recruiting
Registry study for kidney-sparing surgery in adults
This study collects information in people who have a localized kidney tumor that can often be treated with kidney-sparing surgery. It may help doctors understand outcomes and improve care, mainly by building a better national database rather than testing a new drug.
Hof, BavariaAges 18–100 - NCT04691284Recruiting
Test how the gut microbiome changes during major cancer treatment
This study looks at your gut “microbiome” (the bacteria in your intestines) while you receive high-dose chemotherapy and a stem cell transplant, or CAR-T cell therapy. Researchers hope to understand how these treatments affect the microbiome, which may relate to how well patients do.
Bratislava, SlovakiaAges 18 years+ - NCT04692324Recruiting
Test spinal fluid tests to help identify brain tumor types
This study looks at spinal fluid (cerebrospinal fluid, or CSF) to find markers that may signal a brain or spinal tumor or related abnormal growth. If you have a suspected tumor near the CSF spaces, these results may help doctors better classify what’s going on.
Rochester, MinnesotaAges Any age - NCT04710758Recruiting
Keyhole surgery for advanced stomach cancer
This trial looks at laparoscopic (keyhole) total stomach removal for people with advanced stomach cancer in the upper or middle part of the stomach. It aims to see whether this operation approach is safe and useful based on your tumor stage and overall health.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04712539RecruitingPhase 2
Baloxavir and oseltamivir for severe flu in immune-compromised people
This trial tests whether two flu medicines—baloxavir and oseltamivir—work better to treat influenza in people with weakened immune systems (like transplant or blood cancer patients). It may help reduce severe complications, especially when flu affects the lungs or is at high risk to do so.
Houston, TexasAges 12 years+ - NCT04722692RecruitingPhase 3
Delayed sentinel lymph node biopsy for ductal cancer in situ
This trial tests whether doing a sentinel lymph node biopsy later (after breast surgery) is a safe, accurate way to check if cancer has spread. It uses a special tracking shot that helps find the lymph nodes.
Houston, TexasAges 18 years+ - NCT04732065RecruitingPhase 1
ONC206 for certain brain tumors in children and young adults
This Phase 1 study tests ONC206, a new targeted medicine, for diffuse midline gliomas (DMG) with a specific gene change (H3K27 altered) and for some other recurrent brain/spinal cord cancers. It is designed to find the right dose and see whether it can control or shrink tumors after initial treatment or when the cancer returns.
San Francisco, CaliforniaAges 2–21 - NCT04733820RecruitingPhase 3
Extra chemo after surgery for advanced cervical cancer
This Phase 3 trial tests whether adding chemotherapy after surgery helps people with locally advanced cervical cancer, especially when prior treatment didn’t fully match standard guidelines. It looks at whether this “adjuvant” chemotherapy improves outcomes after neoadjuvant chemotherapy and an extensive hysterectomy.
Wuhan, HubeiAges 18–70 - NCT04741945RecruitingPhase 2
Metformin to help prevent leukemia in certain blood disorders
This Phase 2 study tests whether metformin can lower the risk of leukemia developing in people with low-risk myelodysplastic syndrome (LR-MDS) or CCUS. You may be considered if your blood counts have stayed low and other causes have been ruled out.
Copenhagen, Copenhagen NAges 18 years+ - NCT04743479Recruiting
AI screening for pancreatic cancer in higher-risk people
This trial uses an artificial-intelligence tool to help detect pancreatic cancer earlier and track people at higher risk. You may be asked to complete questionnaires and have imaging tests like MRI or CT to see how well the approach works.
ShanghaiAges 50–75 - NCT04744116RecruitingEarly Phase 1
Cord blood cell therapy added to ruxolitinib for steroid-resistant GVHD
This trial studies whether adding cord-blood–derived cells to ruxolitinib can improve steroid-resistant acute graft-versus-host disease (GVHD) affecting the lower gut or liver. It’s meant for people who are not getting better (or are worsening) despite adequate steroid treatment.
Houston, TexasAges 12–80 - NCT04749108RecruitingPhase 2/Phase 3
Tailored treatment for locally advanced rectal cancer after FOLFIRINOX
This trial studies a more customized treatment plan for people with locally advanced rectal (bowel) cancer after they receive FOLFIRINOX chemotherapy. It aims to reduce tumor spread risk and improve outcomes by tailoring the next steps based on scan details and your health status.
Marseille, Bouches Du RhôneAges 18 years+ - NCT04766515Recruiting
Study of immune checkpoint cancer treatment in real life
This is an observational study that follows adults with solid cancer who are receiving immune checkpoint inhibitor treatments. It aims to learn how these medicines are used and what outcomes may look like in everyday care.
ShanghaiAges 18 years+ - NCT04776330RecruitingPhase 1/Phase 2
BCMA-targeted CAR-T for relapsed or refractory multiple myeloma
This trial tests a lab-made immune cell therapy (CAR-T) designed to attack a protein called BCMA on myeloma cells. It’s for adults whose multiple myeloma or related plasma cell disease has come back or didn’t respond to prior treatment, aiming to improve cancer control.
Kunming, YunnanAges 18–75 - NCT04799535Recruiting
Imaging study to detect and monitor breast changes
This study tests special ultrasound and/or MRI imaging to better detect and track breast cancer and related changes over time. You may be asked to have scans around the time of biopsy or during treatment to help doctors see small blood-vessel changes in the breast.
Rochester, MinnesotaAges 18 years+ - NCT04809025Recruiting
Testing biopsy samples vs surgery samples for stomach cancer testing
This study compares two ways of getting stomach cancer tissue: a camera-guided biopsy and a tissue sample taken during planned stomach surgery. The goal is to see which sample better supports molecular (gene-based) testing to guide diagnosis.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04811703RecruitingPhase 1
Testing aerosol chemotherapy through the belly for advanced ovarian cancer
This Phase 1 study tests a new way to deliver chemotherapy inside the abdomen (belly) using a pressurized aerosol during a procedure, along with standard blood (IV) chemotherapy. It may help people with advanced ovarian cancer whose tumors have not progressed but are not removable with surgery yet.
LilleAges 18–75 - NCT04812912Recruiting
Study sexual and reproductive effects in early colon cancer
This study looks at how early-onset colorectal cancer treatment affects reproductive and sexual health over time. It asks eligible people to complete questionnaires so researchers can understand and possibly improve care during and after treatment.
Basking Ridge, New JerseyAges 18–50 - NCT04822077Recruiting
Proton beam treatment for thymus tumors
This trial studies proton radiotherapy (a type of radiation) for cancers of the thymus, like thymoma or thymic carcinoma. It may help improve tumor control while limiting radiation exposure to nearby organs.
Umeå, NorrlandAges 18 years+ - NCT04823923Recruiting
How kidney failure affects drug levels in metastatic kidney cancer
This study looks at how chronic kidney failure changes the amount of certain cancer medicines in the blood. It involves people with metastatic clear cell kidney cancer who take pazopanib or cabozantinib, and compares drug levels in different kidney function groups.
MarseilleAges 18 years+
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Common questions
- Are there clinical trials for neoplasms?
- Yes. Clin2 currently lists 1,691 recruiting neoplasms studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neoplasms trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neoplasms trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.