Clinical trials
Nerve Block clinical trials
Below are recruiting nerve block clinical trials, each written for real people, not researchers. We’re tracking 223 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05487053Recruiting
Nerve block type test after knee replacement
This study compares two pain-control methods for the leg after a total knee replacement: a single injection versus a continuous nerve-block catheter. It aims to see which option helps people recover and do rehab better.
MoscowAges 18 years+ - NCT07130760Recruiting
Testing two numbing methods for tooth pain in a back molar
This trial compares two ways to numb a painful lower back molar. If you have a tooth infection that needs a root canal, you may receive one of two injection techniques to see which works better.
Ferrol, A coruñaAges 18 years+ - NCT06074744Recruiting
Nerve blocks for knee replacement pain relief
This study compares two types of nerve blocks (subsartorial and femoral) to see which provides better pain control after knee replacement surgery. Both are injections that numb the nerves around your knee to help with recovery.
LucerneAges 18 years+ - NCT06806202RecruitingPhase 2
Warm vs. standard numbing medicine for tooth injections
This trial tests if warming the numbing medicine before injecting it into the jaw makes the numbing work better for people with a painful tooth infection. If you have a bad toothache in a lower molar and need a dental procedure, this study might help make the numbing more effective.
Rawalpindi, Punjab ProvinceAges 18–50 - NCT06861387Recruiting
Cryo nerve block for lung surgery pain
This trial tests a freezing technique to numb nerves around the lungs during minimally invasive lung surgery. It may help reduce pain after surgery, so you need less pain medication.
Nieuwegein, UtrechtAges 18 years+ - NCT06984276Recruiting
Nerve blocks for pain relief in children having heart surgery
This study compares two different ultrasound-guided numbing injections (pectoral nerve block vs. transverse thoracic plane block) to see which provides better pain control for children aged 6 months to 7 years undergoing heart surgery through a chest incision with a heart-lung machine.
CairoAges 6 months–7 years - NCT06734975RecruitingPhase 2
Nerve block for better recovery after vocal cord surgery
This study tests if a nerve block can help reduce pain and improve recovery after surgery to remove a noncancerous growth on the vocal cords. Participants will be randomly assigned to receive either the nerve block or standard care.
Newark, New JerseyAges 18 years+ - NCT07049094RecruitingPhase 4
Scalp nerve block for pain after brain surgery
This trial tests if a long-lasting numbing medicine (bupivacaine liposomes) injected into scalp nerves can reduce pain after brain surgery. It may help you need less pain medicine and feel better after your operation.
Hangzhou, ZhejiangAges 18 years+ - NCT06639022Recruiting
Pain relief after cervical spine surgery
This study compares two types of nerve blocks to see which provides better pain relief after neck surgery. It looks for patients scheduled for a specific neck procedure called anterior cervical discectomy.
Altındağ, AnkaraAges 18–80 - NCT07134660Recruiting
Comparing two numbing medicines for lung surgery pain
This study compares two types of numbing medicine (liposomal vs. hydrochloride bupivacaine) injected near the ribs during lung surgery. The goal is to see which one provides better pain relief after the operation.
ShanghaiAges 18–80 - NCT06873893Recruiting
Nerve blocks for pain relief after mastectomy surgery
This study compares two types of ultrasound-guided nerve blocks to see which one provides better pain relief after a mastectomy. The blocks are injected near the chest wall to numb the area during and after surgery.
Cairo , AbbassyaAges 35–65 - NCT07712406Recruiting
Nerve block for lower back pain from nerve entrapment
This trial tests whether a nerve block can help people with chronic lower back or buttock pain caused by a trapped nerve near the hip bone. You may be eligible if you have had this pain for at least 3 months and it did not get better with other treatments.
Gaziosmanpaşa, IstanbulAges 18–75 - NCT06857110Recruiting
Nerve block vs. hematoma block for wrist fracture pain
This study compares two ways to manage pain when a broken wrist is realigned without surgery: a nerve block near the elbow vs. a numbing injection directly into the fracture. It may help researchers find which method works better and is more comfortable for you.
Bogotá, Bogota D.C.Ages 18 years+ - NCT06886815Recruiting
Nerve block for Achilles tendon repair surgery
This trial tests if a nerve block in the back of the knee improves pain control after surgery to repair a torn Achilles tendon. It may help you recover more comfortably as a day surgery patient.
Toronto, OntarioAges 18–65 - NCT07626346Recruiting
Pain relief medication added to shoulder surgery nerve block
This trial tests whether adding a medication called dexmedetomidine to a numbing injection around shoulder nerves can improve pain control after laparoscopic shoulder surgery. The goal is to see if this combination works better than the numbing medication alone.
CairoAges 18–65 - NCT05925465Recruiting
Nerve block during elective facial surgery
This study tests a numbing “nerve block” to see how well it controls pain for people having planned facial/jaw surgery. If you’re eligible, you’d receive the study’s nerve-block approach during your operation.
Al Mansurah, MansouraAges 18–60 - NCT06676098Recruiting
Best spot for a guided numbing shot for root canals
This study compares different injection spots for a new device that helps numb lower back teeth before root canal treatment. If you need a root canal on a lower molar or premolar, you may be able to help find the best spot for the numbing shot.
Boston, MassachusettsAges 18 years+ - NCT07347067Recruiting
Trigger point injections for chronic migraine
This study tests if injecting medication into specific painful spots in your muscles (called trigger points) can help reduce chronic migraine pain. It may be an option if you've tried other treatments but still have significant pain.
Beijing, Beijing MunicipalityAges 18–65 - NCT07493213Recruiting
Ultrasound-guided shoulder injections for frozen shoulder
This study tests whether ultrasound-guided injections into the shoulder can improve pain and movement in people with frozen shoulder. It may help if you have had shoulder pain for at least 3 months and other treatments haven't worked well.
Konya, SelçukluAges 18–75 - NCT06069154Enrolling by invitation
Freezing nerves for rib fracture pain
This study tests a procedure called cryoneurolysis, which uses cold to temporarily freeze nerves near broken ribs to relieve pain. It is for adults who have 1 to 6 recently broken ribs with at least moderate pain and are already getting a nerve block injection.
La Jolla, CaliforniaAges 18 years+ - NCT07233538Recruiting
Numbing injection before nose surgery for better pain relief
This study tests a numbing injection in the cheek area before septorhinoplasty to see if it improves pain control and reduces the need for strong IV pain medicine. It may help you have a smoother recovery with less discomfort.
Ankara, YenimahalleAges 18–65 - NCT06773780Recruiting
Comparing two pain blocks for TAVI heart valve replacement
This study compares two types of ultrasound-guided nerve blocks (pain shots) given before a TAVI procedure to see which one provides better pain relief after surgery. If you are scheduled for a TAVI and meet the health criteria, you may be able to participate.
IstanbulAges 18–85 - NCT06784882RecruitingPhase 4
Continuous vs. single-injection nerve block for outpatient knee replacement
This trial compares two types of nerve blocks for pain control after total knee replacement. You will receive either a one-time injection or a continuous block that delivers medication through a small tube. The goal is to see which method provides better pain relief while allowing you to go home the same day.
La Jolla, CaliforniaAges 18 years+ - NCT07483190Recruiting
Nerve block for pain after laparoscopic hysterectomy
This study tests a nerve block called M-TAPA to reduce pain after laparoscopic hysterectomy. It may help you need less pain medicine and recover more comfortably.
IstanbulAges 18–70
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Common questions
- Are there clinical trials for nerve block?
- Yes. Clin2 currently lists 223 recruiting nerve block studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a nerve block trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a nerve block trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.