Clinical trials · Raleigh–Durham, NC
Obesity & Overweight clinical trials in Raleigh–Durham
We’re tracking 15 recruiting obesity & overweight studies with a site in or near Raleigh–Durham — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Raleigh–Durham
- NCT06857942RecruitingPhase 4
Tirzepatide added to ixekizumab for psoriasis and weight issues
This trial tests whether adding tirzepatide (a weight-loss and diabetes drug) to ixekizumab (a psoriasis treatment) helps people with moderate-to-severe psoriasis who are overweight or have obesity. It is for those already taking ixekizumab for about 3 months.
Cary, North CarolinaAges 18 years+ - NCT06671119Recruiting
Weight regain treatment after sleeve gastrectomy with mucosal ablation
This trial tests a procedure to help people who have regained weight after a sleeve gastrectomy. It uses a special technique to treat the stomach lining and may help you lose weight again.
Cary, North CarolinaAges 22–60 - NCT06734312Recruiting
Stomach procedure to maintain weight loss after GLP-1s
This study is for people who have lost weight using semaglutide or tirzepatide and are stopping that medication. It tests a stomach procedure (called mucosal ablation) to see if it can help you keep the weight off after stopping the drug.
Cary, North CarolinaAges 21–65 - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Raleigh, North CarolinaAges 18 years+ - NCT07575399RecruitingPhase 3
Switching to a New Weight-Loss Medication From Current GLP-1
This trial tests whether switching from your current GLP-1 medication (like Ozempic or Wegovy) to a new drug called maridebart cafraglutide works as well or better for weight management. You must have already lost at least 10% of your body weight on your current GLP-1 and be doing well with it.
Raleigh, North CarolinaAges 18–99 - NCT07743463RecruitingPhase 3
Daily pill for weight loss in adults with excess weight or weight-related health issues
This study tests a once-daily pill called ASC30 to help adults with obesity or overweight who also have conditions like high blood pressure, sleep apnea, or heart disease lose weight. The pill may work by affecting appetite and blood sugar, and the study aims to see how effective and safe it is.
Raleigh, North CarolinaAges 18 years+ - NCT07743450RecruitingPhase 3
Daily oral medication for weight loss in adults with obesity and type 2 diabetes
This study tests a once-a-day pill for adults who are overweight or have obesity and also have type 2 diabetes. The goal is to see if the medication helps with weight loss and improves blood sugar control.
Raleigh, North CarolinaAges 18 years+ - NCT07037433RecruitingPhase 3
Heart protection study for people with heart disease and overweight
This study tests a new weekly injection (maridebart cafraglutide) to see if it helps lower the risk of heart problems in people with heart disease and overweight. It is for adults who have had a heart attack, stroke, or artery blockages and also have a BMI of 27 or higher.
Raleigh, North CarolinaAges 45–99 - NCT07720271RecruitingPhase 3
Zenagamtide weight loss study for adults
This study is testing a new tablet called Zenagamtide to help people with extra body weight lose weight. It's for adults who are not diabetic and haven't used similar weight loss drugs before.
Raleigh, North CarolinaAges 18 years+ - NCT03885245RecruitingPhase 2
L-citrulline supplement for overweight adults with later-onset asthma
This Phase 2 trial tests whether adding L-citrulline can improve asthma control in overweight adults whose asthma started later in life. It compares your asthma symptoms and lung testing results to see if the supplement helps when asthma is already being treated.
Durham, North CarolinaAges 18–65 - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Durham, North CarolinaAges 18–79 - NCT07654361RecruitingPhase 3
A new pill for weight loss in obesity and overweight
This study tests an investigational pill called aleniglipron to see if it helps people with obesity or overweight who also have a weight-related health problem (like high blood pressure) lose weight safely. It is a Phase 3 trial, meaning it is in the final stages before seeking approval.
Durham, North CarolinaAges 18–79 - NCT06672549RecruitingPhase 3
Weight loss medication study for children with obesity
This trial tests a medication for children and teens with obesity or overweight who have not been able to lose enough weight with diet and exercise alone. It aims to see if a new treatment can help them safely lose weight and improve related health problems.
Durham, North CarolinaAges 6–17 - NCT06724406Recruiting
Family weight loss program for Black adults
This study tests a family-centered weight loss program for Black adults and their family members. You and a family member or partner will work together to lose weight and improve health.
Chapel Hill, North CarolinaAges 18–75 - NCT07392190RecruitingPhase 3
Study of eloralintide for people with persistent obesity
This trial tests if adding eloralintide helps people who are still obese or overweight while taking weekly incretin therapy. It aims to support additional weight loss for those who haven't reached their goals.
Chapel Hill, North CarolinaAges 18 years+
Hear when a new Obesity & Overweight trial opens near Raleigh–Durham, NC
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Obesity & Overweight trials in other cities
Where these studies are running near Raleigh–Durham
Institutions with a site for the recruiting obesity & overweight studies listed above.
- Accellacare · 2 studies
- True You Weight Loss · 2 studies
- Accellacare of Raleigh
- ACCOMPLISH-1 Research Site
- ACCOMPLISH-2 Research Site
- AURORA-1 Clinical Site
- AURORA-2 Clinical Site
- Duke Children's Primary Care
What taking part in a obesity & overweight study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting obesity & overweight studies in North Carolina.
Common questions
- Are there obesity & overweight clinical trials near Raleigh–Durham?
- Yes. We're currently tracking 15 recruiting obesity & overweight studies with a site near Raleigh–Durham, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a obesity & overweight study near Raleigh–Durham?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Raleigh–Durham to take part?
- Not necessarily. These studies have a site near Raleigh–Durham, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a obesity & overweight trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New obesity & overweight studies open near Raleigh–Durham regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.