Clinical trials
Obesity Type 2 Diabetes Mellitus clinical trials
Below are recruiting obesity type 2 diabetes mellitus clinical trials, each written for real people, not researchers. We’re tracking 160 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07513168RecruitingPhase 4
Low-dose semaglutide for weight loss in obese adults
This study tests whether a low dose of semaglutide (a once-weekly injection) can help obese adults without diabetes lose weight. Semaglutide works by reducing appetite and helping your body use food differently.
Hyderābād, SindhAges 18 years+ - NCT07284979RecruitingPhase 3
Weekly injection for obesity without diabetes
This trial tests a new once-weekly injection called Ribupatide for weight loss in people with obesity who do not have diabetes. It compares the study drug to an existing medication (semaglutide) and a placebo to see how well it works and if it's safe.
Glendale, ArizonaAges 18 years+ - NCT06542718Recruiting
Studying glucose patterns in Asian women with gestational diabetes
This study monitors blood sugar levels during pregnancy in overweight Asian women to better understand gestational diabetes. It uses a continuous glucose monitor to track patterns and may help improve care for mothers and babies.
SingaporeAges 21–45 - NCT05840497Recruiting
Exercise program to help lower gestational diabetes risk
This trial tests whether a strength and resistance exercise program during pregnancy can help reduce gestational diabetes in people who are overweight or obese. It may help by improving how your body handles sugar during pregnancy.
Pamplona, NavarreAges 18 years+ - NCT06856291Recruiting
Semaglutide for obesity with different insulin resistance levels
This study tests whether semaglutide (a weight-loss medication) works differently in people with varying degrees of insulin resistance (how well your body uses sugar). If you are obese without diabetes, you may be able to join.
Aarau, Canton of AargauAges 18–60 - NCT07101939RecruitingPhase 2
Studying a medicine to preserve muscle during weight loss
This trial tests a new medicine, (S)-pindolol benzoate, given along with semaglutide (Ozempic/Wegovy). The goal is to see if it helps people lose mostly fat instead of muscle while on a weight loss program.
BelgradeAges 18–75 - NCT07284875RecruitingPhase 3
Ribupatide for weight loss in adults without diabetes
This trial tests a new medication, Ribupatide, to see if it helps people with obesity or overweight who also have weight-related health problems. You cannot have diabetes to join.
Anniston, AlabamaAges 18 years+ - NCT07070765Recruiting
Study on dapagliflozin to protect the heart during breast cancer chemo
This trial tests if a heart-protecting drug called dapagliflozin can help prevent heart damage in breast cancer patients receiving a type of chemotherapy called anthracycline. It may be an option if you have low to medium heart risk factors.
Aberdeen, AberdeenshireAges 18–70 - NCT05195944Enrolling by invitationPhase 4
Semaglutide versus sitagliptin after liver transplant for diabetes
This trial compares two diabetes medicines—semaglutide and sitagliptin—in people who have had a liver transplant and have type 2 diabetes (or diabetes after transplant). It’s looking to see which medicine works better and is safe for blood sugar control in the transplant setting.
Toronto, OntarioAges 18 years+ - NCT04101669Recruiting
Diabetes device trial to improve blood sugar and weight
This study tests the RESET System to help people with type 2 diabetes lower their average blood sugar (HbA1c) despite current medication. It may also affect weight and safety outcomes by changing how food moves through the gut.
Washington D.C., District of ColumbiaAges 22–65 - NCT07403604RecruitingPhase 1
Lowering Insulin to Reduce Fat Buildup in the Liver
This study tests if lowering insulin levels can reduce fat buildup in the liver for people with a fatty liver condition called MASLD. It's looking for adults who are overweight and have early signs of insulin resistance but not diabetes.
New York, New YorkAges 18–65 - NCT06446531RecruitingPhase 1
Preventing diabetes progression in Hispanic adults
This trial tests if a medication can prevent or slow the progression from prediabetes to type 2 diabetes and reduce heart risk. It is for Hispanic adults who are overweight and have prediabetes.
San Antonio, TexasAges 18 years+ - NCT04643262Enrolling by invitation
Looking back at bariatric surgery outcomes in obesity
This study looks back at people who had sleeve gastrectomy (a weight-loss operation) and compares results and complications. It may be a fit if you match the study’s age, weight, and health history, though it’s a “retrospective” review, so it mainly uses past records.
Ages 18–68 - NCT06511310Recruiting
Exercise, brain health, and weight maintenance after weight loss surgery
This study looks at how exercise affects brain activity and helps people keep weight off after they have regained some weight following bariatric surgery. You may join if you had weight loss surgery, lost weight, and then regained more than 10% of that lost weight within the last 1 to 5 years.
Boston, MassachusettsAges 18–70 - NCT06759701RecruitingEarly Phase 1
Weight loss drug before prostate cancer surgery pilot study
This study tests if taking tirzepatide (a weight loss medicine) before prostate removal surgery is safe and helpful for overweight men with intermediate-risk prostate cancer. It aims to see if losing weight can improve surgery outcomes.
Houston, TexasAges 18 years+ - NCT07504068Recruiting
Exercise and supplement for metabolic health in overweight adults
This trial tests whether a combination of physical exercise and a nutritional supplement can improve body composition, metabolism, and overall health in adults who are overweight and have early signs of metabolic problems. It may help you if you are looking for a non-drug approach to boost your health.
Valencia, ValenciaAges 50–65
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Common questions
- Are there clinical trials for obesity type 2 diabetes mellitus?
- Yes. Clin2 currently lists 160 recruiting obesity type 2 diabetes mellitus studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity type 2 diabetes mellitus trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity type 2 diabetes mellitus trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.