Clinical trials · California
Obesity clinical trials in California
We’re tracking 118 recruiting obesity studies with a site in California — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07845500RecruitingPhase 3
Monthly shot to help keep weight off after switching from semaglutide or tirzepatide
This study tests a new once-a-month medicine for people who have already been taking a weight-loss medication and want to keep the weight off. Participants will switch from their current medicine (semaglutide or tirzepatide) to the study drug.
Los Angeles, CaliforniaAges 18 years+ - NCT07794579RecruitingPhase 3
Study of orforglipron for people with overweight at risk of health problems
This trial tests a new medicine, orforglipron, to help people with overweight who are at risk of developing weight-related health issues. It aims to see if the medicine can help with weight management and reduce risks before more serious conditions develop.
Lake Forest, CaliforniaAges 18 years+ - NCT07595549RecruitingPhase 3
Testing Berobenatide for Weight Loss in Overweight Adults
This study tests a new medicine called berobenatide to help people with overweight or obesity lose weight. The medicine may also help improve related health conditions like high blood pressure, high cholesterol, or type 2 diabetes.
Canoga Park, CaliforniaAges 18 years+ - NCT05606731Recruiting
Family coaching to help prevent childhood weight gain
This study offers a family-focused program for Latino adult caregivers of young children to help prevent childhood obesity. If your child is already overweight, the program may help you learn practical ways to support healthier habits as a family.
Los Angeles, CaliforniaAges 2 years+ - NCT06924320RecruitingPhase 1/Phase 2
Study of two medicines for weight loss and diabetes
This study tests two investigational medications, MET233 and MET097, in people with obesity or overweight, with or without type 2 diabetes. It aims to see if the combination can help with weight loss and blood sugar control.
Cypress, CaliforniaAges 18–75 - NCT07855133RecruitingPhase 1
Switching to a new treatment for weight or diabetes
This study tests a new medicine called zenagamtide for adults with overweight or obesity, with or without type 2 diabetes, who are currently taking semaglutide. The goal is to see how well people tolerate switching from semaglutide to the new treatment.
Glendale, CaliforniaAges 18 years+ - NCT07868354RecruitingPhase 1
Switching to a new weight-loss medicine from tirzepatide
This study tests how well adults with overweight or obesity, with or without type 2 diabetes, tolerate switching from their current weight-loss medication (tirzepatide) to a new medicine called zenagamtide. It may help you understand if this new option is easier on your stomach.
Glendale, CaliforniaAges 18 years+ - NCT04721873RecruitingPhase 2
Weight-loss medicine for people with ulcerative colitis
This study tests whether a weight-loss medication, along with usual ulcerative colitis care, can help people who have both ulcerative colitis and obesity. It focuses on people with active symptoms or who need ongoing steroid medicine, and it also checks safety with heart, blood, infection, and mental-health screenings.
La Jolla, CaliforniaAges 18–80 - NCT06254768Recruiting
Continuous glucose monitors for kids with obesity
This study tests if using a continuous glucose monitor (CGM), a small device that tracks blood sugar, can help children and teens with obesity understand their body better and improve their health.
Los Angeles, CaliforniaAges 10–21 - NCT07843485RecruitingPhase 3
Weight loss medication for adults with type 2 diabetes
This study tests a new medicine called petrelintide to help people with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be an option if you've struggled with weight loss through diet alone.
Los Angeles, CaliforniaAges 18 years+ - NCT07843472RecruitingPhase 3
Petrelintide for weight loss in people with heart disease
This study tests a new medication called petrelintide to help people with overweight or obesity and heart disease lose weight. It may offer a new way to manage weight and improve heart health.
Los Angeles, CaliforniaAges 40 years+ - NCT07846033RecruitingPhase 1
Study of the experimental drug VK3019 for adults with overweight or obesity
This early-phase study tests an experimental medicine called VK3019 in adults who are overweight or have obesity but are otherwise healthy. The goal is to see if the drug is safe and how the body handles it, which may lead to future weight-management options.
Lake Forest, CaliforniaAges 18–60 - NCT07838740RecruitingPhase 1
Weekly weight-loss medication for healthy adults with obesity
This early-stage trial tests a new once-weekly medication (VK2735) that may help with weight loss. It's for healthy adults with obesity who do not have other significant health problems like diabetes.
Lake Forest, CaliforniaAges 18–60 - NCT07823608RecruitingPhase 3
Monthly study medicine for adults with sleep apnea and overweight who use a breathing machine
This study tests an investigational medicine taken once a month for adults with moderate to severe sleep apnea who are overweight or have obesity and use a CPAP or similar breathing machine. It aims to see if the medicine improves sleep-related breathing.
Riverside, CaliforniaAges 18 years+ - NCT07817875RecruitingPhase 3
Tirzepatide for weight loss in children aged 6 to under 12
This study tests a once-weekly medication called tirzepatide to help children aged 6 to under 12 with obesity lose weight. It compares the medication to a placebo (inactive shot) to see if it safely helps with weight loss in this age group.
Loma Linda, CaliforniaAges 6–11 - NCT07784270RecruitingPhase 3
Weight loss injection for adults with type 2 diabetes and overweight
This study tests a new injected medicine that may help people with type 2 diabetes and overweight or obesity lose weight. The trial will see how well it works and if it is safe compared to a placebo.
Gardena, CaliforniaAges 18 years+ - NCT07784725RecruitingPhase 3
Study of a weight loss injection for adults with obesity
This study tests a new medicine to help adults with obesity or overweight lose weight. It's for people who have had trouble losing weight in the past and don't have diabetes.
Escondido, CaliforniaAges 18 years+ - NCT07776509RecruitingPhase 3
Adding a new drug to current weight-loss therapy for adults with obesity or overweight
This study tests a new medication (AZD6234) added to your current weight-management medication (an incretin-based drug) to see if it helps with weight loss. You may be eligible if you are overweight or obese with related health issues or type 2 diabetes.
Escondido, CaliforniaAges 18 years+ - NCT07776678Recruiting
Body fat and muscle measurement study
This study uses advanced body scans (like MRI and DXA) to better measure body fat and muscle. It may help improve how obesity is diagnosed and treated.
Menlo Park, CaliforniaAges 18 years+ - NCT07752979RecruitingPhase 2
New drug for weight loss in adults with obesity or overweight
This study tests an investigational drug called ABBV-295 to see if it helps adults with obesity or overweight who have weight-related health conditions lose weight. It may offer a new treatment option for managing weight and improving overall health.
Concord, CaliforniaAges 18–75 - NCT07743450RecruitingPhase 3
Daily oral medication for weight loss in adults with obesity and type 2 diabetes
This study tests a once-a-day pill for adults who are overweight or have obesity and also have type 2 diabetes. The goal is to see if the medication helps with weight loss and improves blood sugar control.
Banning, CaliforniaAges 18 years+ - NCT07743463RecruitingPhase 3
Daily pill for weight loss in adults with excess weight or weight-related health issues
This study tests a once-daily pill called ASC30 to help adults with obesity or overweight who also have conditions like high blood pressure, sleep apnea, or heart disease lose weight. The pill may work by affecting appetite and blood sugar, and the study aims to see how effective and safe it is.
Banning, CaliforniaAges 18 years+ - NCT07731139RecruitingPhase 1
Testing a new medicine for people with obesity
This study tests how different amounts of the study medicine PF-08642534 are tolerated and how they work in the body of people with obesity. It aims to find a safe dose for future studies.
Lake Forest, CaliforniaAges 18–70 - NCT07685808RecruitingPhase 2
Testing a weight loss injection for people with overweight or obesity
This study tests an injectable medication called Olatorepatide to help people with overweight or obesity lose weight. It is only for people without diabetes who meet specific body mass index (BMI) requirements.
Walnut Creek, CaliforniaAges 18 years+
Obesity trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting obesity studies listed above.
- Diablo Clinical Research · 4 studies
- Research Site · 3 studies
- California Clinical Trials Medical Group managed by PAREXEL · 2 studies
- Institute for Metabolic Research Los Angeles · 2 studies
- Orange County Research Center · 2 studies
- University Clinical Investigators, Inc. · 2 studies
- Viking Clinical Site #001 · 2 studies
- Altasciences Clinical Los Angeles, Inc.
What taking part in a obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Obesity trials in other states
Common questions
- Are there obesity clinical trials in California?
- Yes. We're currently tracking 118 recruiting obesity studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a obesity study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New obesity studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.