Clinical trials · California
Obesity clinical trials in California
We’re tracking 115 recruiting obesity studies with a site in California — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06824974Recruiting
Time-restricted eating for liver disease or cancer
This study tests whether combining time-restricted eating with healthy eating helps people with metabolic liver disease, cirrhosis, or early-stage liver cancer. If you are overweight and currently fast less than 12 hours at night, this diet approach might improve your health.
La Jolla, CaliforniaAges 18 years+ - NCT06891352Recruiting
Timing meals to reduce disease risk in night shift workers
This study tests whether adjusting when you eat (time-restricted eating) can improve health in night shift workers. You would use a smartphone app to track your meals and follow a set eating schedule for up to a year.
La Jolla, CaliforniaAges 18–70 - NCT06897982Recruiting
Nutrition program for prediabetes at health center
This study tests a nutrition program for people with prediabetes at a health center. It aims to see if the program is practical and can help prevent type 2 diabetes.
Los Angeles, CaliforniaAges 18–99 - NCT06994338RecruitingPhase 2
Tirzepatide for alcohol use disorder
This study tests whether a medication called tirzepatide (a once-weekly injection) can help people reduce their alcohol consumption. It is for people who drink heavily, have a high BMI, and are actively seeking help to drink less.
Los Angeles, CaliforniaAges 21–65 - NCT07013643RecruitingPhase 1
How a new weight-loss drug affects birth control pills
This study checks if a new weight-loss medicine changes how the body handles birth control pills. It is for healthy women with overweight or obesity.
Glendale, CaliforniaAges 35–75 - NCT07044570Recruiting
Examining attitudes in physical activity engagement
This trial tests if a program can help people who are not very active start and stick with a physical activity routine. Participants will wear a study-provided smartwatch to track their activity and answer brief surveys.
Los Angeles, CaliforniaAges 18 years+ - NCT07209202Recruiting
Study on Fructose Handling in Obesity
This study looks at how the body handles fructose (a natural sugar) in people with different weights. It may help explain why some people process sugars differently.
Vallejo, CaliforniaAges 20–55 - NCT07316816Recruiting
Weight loss study for teens with severe obesity
This study evaluates how continuous glucose monitors and other wearable devices can help teens in a bariatric program lose weight. You may join if you are in the program and ready for sleeve gastrectomy or GLP-1 medication.
Palo Alto, CaliforniaAges 10–18 - NCT02024542Recruiting
How the body changes after bariatric surgery
This study looks at how metabolism (how your body handles food and energy) responds after weight-loss surgery. It may help researchers understand what changes to expect in people with diabetes or prediabetes and cholesterol problems.
Sacramento, CaliforniaAges 18–55 - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70 - NCT07446439RecruitingPhase 3
Tradipitant for nausea from weight loss injections
This study tests whether the drug tradipitant can help reduce nausea and vomiting caused by weight loss injections like Ozempic or Wegovy. If you have these side effects and are not diabetic, you may be eligible.
Los Angeles, CaliforniaAges 18–65 - NCT07478263Recruiting
Healthy eating trial for Latinas to prevent type 2 diabetes
This study tests a behavioral program designed to help Latinas with prediabetes improve their nutrition and eating patterns to prevent type 2 diabetes. It focuses on reducing cravings and building healthy habits.
La Jolla, CaliforniaAges 18–55 - NCT07481630RecruitingPhase 3
Testing a new medicine for weight loss and knee pain
This study tests if a new medicine called NNC0487-0111 can help people with extra weight and knee osteoarthritis lose weight and reduce knee pain. If you have knee pain most days and are willing to stop pain relievers for short periods, you may be able to join.
Walnut Creek, CaliforniaAges 18 years+ - NCT07503210RecruitingPhase 3
Study of a new medicine to maintain weight loss
This study tests an investigational medicine to help people who have lost weight keep it off. It's for adults without diabetes who haven't used similar weight-loss drugs before.
Walnut Creek, CaliforniaAges 18 years+ - NCT07509307RecruitingPhase 3
Study of a new medicine for weight loss and knee pain in osteoarthritis
This trial tests if a new medicine, NNC0487-0111, can help people with excess weight and knee osteoarthritis lose weight and reduce knee pain. It is for people who have had knee pain for at least three months and who can stop taking pain relievers for short periods before study visits.
Escondido, CaliforniaAges 18 years+ - NCT07533175RecruitingPhase 3
Testing a new weight-loss medicine for type 2 diabetes
This study tests whether a new medicine called NNC0487-0111 helps people with type 2 diabetes and excess weight lose weight. You'll take the medicine along with your current diabetes care to see if it works better than standard treatment.
Escondido, CaliforniaAges 18 years+ - NCT07571005RecruitingPhase 3
Testing a New Weight-Loss Medicine for Sleep Apnea
This study tests whether a new injectable medicine called NNC0487-0111 helps people with excess weight and moderate-to-severe obstructive sleep apnea (a condition where breathing stops repeatedly during sleep) lose weight and improve their sleep apnea—without needing a CPAP machine. The goal is to see if better weight loss can reduce sleep apnea symptoms.
San Diego, CaliforniaAges 18 years+ - NCT07607587RecruitingPhase 1
Testing a new weight-loss drug for people who couldn't tolerate GLP-1 shots
This study tests a new injectable medication called cagrilintide for people with obesity who had to stop GLP-1 drugs (like Ozempic or Wegovy) because of stomach problems. The goal is to see if cagrilintide causes fewer stomach side effects while still helping with weight.
Walnut Creek, CaliforniaAges 18 years+ - NCT04708535Enrolling by invitation
Study how fat changes affect insulin resistance after bariatric surgery
This study looks at how your body’s fat under the skin and inside the abdomen may affect “insulin resistance,” a common problem linked with blood sugar control. It’s for people who are scheduled for bariatric (weight-loss) surgery, to learn more before and after surgery.
Stanford, CaliforniaAges 30–65
Obesity trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting obesity studies listed above.
- Diablo Clinical Research · 4 studies
- Altman Clinical and Translational Research Institute
- Artemis Institute for Clinical Research
- Cedars-Sinai Medical Center
- Desert Oasis Healthcare Medical Group
- First Valley Medical Group
- Headlands Research - AMCR Institute
- Keck Medicine of USC
What taking part in a obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Obesity trials in other states
Common questions
- Are there obesity clinical trials in California?
- Yes. We're currently tracking 115 recruiting obesity studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a obesity study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New obesity studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.