Observational Study clinical trials

Heart artery function test after a heart attack

This study looks at how well the blood vessels in your arm relax after a heart attack. It uses an ultrasound test on your arm, a heart ultrasound, and some blood tests to see if this can help predict future heart problems.

Guselkumab for Crohn's after ustekinumab

This study looks at whether guselkumab, a different biologic medicine, can help people with Crohn's disease who have already tried ustekinumab but it didn't work well or caused side effects. It aims to see if switching to guselkumab is safe and effective.

Spinal Fusion Recovery in Older Adults

This study is looking at how older adults recover after spinal fusion surgery, a type of back surgery that connects bones in the spine. The goal is to find factors that help people heal faster and feel better afterward.

Study on spinal fluid pressure management in shunt surgery

This study watches how the pressure of spinal fluid around the brain and spine changes during surgery for communicating hydrocephalus. It aims to help doctors better manage a shunt that drains extra fluid from the lower back to the belly.

Cardiac imaging study for inflammatory heart diseases

This study uses heart scans (MRI or nuclear imaging) to better understand inflammatory heart conditions. If you have a suspected inflammatory heart disease and are already scheduled for one of these scans, you may be able to join.

ALS, MND, or PLS registry study

This observational study creates a registry for people with ALS, MND, or PLS. It helps researchers better understand these conditions and find possible treatments.

TCM tools for inflammatory bowel disease

This study compares people with Crohn’s disease or ulcerative colitis to healthy volunteers to see if traditional Chinese medicine tools can help identify unique features of these conditions, like changes in tongue coating. It aims to improve how we diagnose and understand inflammatory bowel disease.

CT Imaging and Clinical Features to Predict Outcomes in Patients With Gastric Cancer

An Unblinded, Single Arm, Pilot Observational Study to Test the Safety, Tolerability, Immunogenicity and the Biological Effects of TRB-001 Vaccination in Individuals Who Have Previously Undergone aSyn Immunotherapy

The Effect of Ultrasonographic Airway Measurements and Anatomical Differences on Laryngeal Mask Placement in Young and Older Adults: A Prospective Observational Study

Study of data analytics for people with genetic conditions

This is an observational study that collects health and family history information to see how advanced data analysis can help people with genetic conditions. It may involve website forms, optional conversations, and sometimes an NIH visit, depending on your situation.

Darolutamide Plus Hormone Therapy for Prostate Cancer in China

This study watches how well a drug called darolutamide works when combined with hormone therapy for men with prostate cancer that has returned after previous treatment. The goal is to understand if this combination helps prevent cancer spread and is safe to use.

Diabetes Study for Medicaid Members in South Carolina

This study collects blood samples and health information from people with type 2 diabetes and healthy controls to learn more about diabetes. It may help improve future care for diabetes.

Airway management study during anesthesia with intubation

This study observes how breathing tube placement (intubation) and other airway care are done during general anesthesia in the operating room and in other anesthesia settings. It may help improve airway management practices in different clinical environments, but you would typically not receive a new treatment as part of an experimental trial.

Comparing two pain blocks for children having testicle surgery

This study compares two pain-relief techniques (erector spinae plane block vs. caudal block) in children aged 1 to 7 years undergoing orchiopexy (surgery for an undescended testicle). The goal is to see which method provides better pain control after surgery. Your child must be generally healthy and meet specific criteria to participate.

Observational study of VYKAT XR for Prader-Willi syndrome

This study follows people with Prader-Willi syndrome who are already taking or starting VYKAT XR, including those switching from an earlier version of the drug (DCCR). It aims to understand how the treatment works in everyday life.

Health checkup trends study for regular participants

This study follows healthy adults who get regular checkups at a specific hospital. It looks at health trends over time to understand wellness in this group, which could help improve preventive care.

Observational study of octreotide depot injections for acromegaly

This study watches how patients with acromegaly respond to octreotide, a medication given as injections under the skin. Researchers will collect information about how well the treatment works and any side effects you experience.

Study registry for advanced endoscopy treatments

This study keeps a record of people who choose an advanced endoscopy procedure (like ESD, EMR, advanced polypectomy, POEM, or treatment for Zenker’s). It aims to learn about real-world outcomes and safety, which may help improve care for future patients.

AI tool to predict pneumonia after heart surgery

This study uses artificial intelligence to help predict if patients might develop pneumonia after heart or blood vessel surgery. It aims to find warning signs early so doctors can act sooner.

Studying a tool to spot confusion in intensive care patients

This study tests a new way to check for delirium (sudden confusion) in patients staying in the intensive care unit (ICU). It also looks at how family members can help spot these changes, so the care team can help sooner.

Treating progressive familial intrahepatic cholestasis

This study tracks treatments and outcomes for people with a confirmed genetic form of PFIC, a rare liver disease. It helps doctors learn which treatments work best for each type.

Lymphovenous bypass to prevent leg swelling after groin lymph node removal

This study looks at whether a surgical procedure called lymphovenous bypass can help prevent leg swelling (lymphedema) after lymph node removal from the groin or pelvis. Researchers will observe patients who undergo this bypass to see if it reduces swelling compared to traditional recovery.

Study of hospital patients admitted for fever

This observational study looks at information from people admitted to the hospital for fever. It does not test a new treatment; it mainly helps doctors learn how fever cases present and progress in the hospital.