Clinical trials
Older Adults (65 Years and Older) clinical trials
Below are recruiting older adults (65 years and older) clinical trials, each written for real people, not researchers. We’re tracking 163 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05574127RecruitingPhase 2
Behavioral therapy for depression in older cancer survivors
This trial tests a brief behavioral program to help older adults (65+) who have had cancer and are feeling depressed. It focuses on teaching simple, practical skills to improve mood and daily activity, delivered over video or phone.
New York, New YorkAges 65 years+ - NCT07424586RecruitingEarly Phase 1
Better recovery for older adults with ostomy surgery
This study tests a program to help adults aged 65 and older recover well after ostomy surgery (a surgery that creates an opening on the belly for waste to leave the body). It also involves their healthcare providers.
Boston, MassachusettsAges 18 years+ - NCT07414017Recruiting
Virtual reality exercise for older adults with low back pain
This study tests if using virtual reality during exercise helps older adults with long-term low back pain. You'll do exercises while focusing your attention in different ways, and researchers will see which method works best for reducing pain and improving movement.
Center, Kirşehi̇rAges 65–80 - NCT06963125Recruiting
Prune juice for constipation in older adults
This study tests whether drinking prune juice can improve bowel movements, reduce constipation symptoms, and enhance quality of life in older adults who have trouble going to the bathroom regularly.
Chiayi City, Chiayi CountyAges 65–100 - NCT06940037Recruiting
Aging biology and strength training in older adults
This study looks at how aging affects the way older adults respond to resistance training (exercises using weights or resistance bands). It compares two types of training to see which works better for improving mobility and strength.
Boston, MassachusettsAges 65 years+ - NCT06305741Recruiting
Anxiety help for older Latino adults with cancer and their caregivers
This study tests a program to reduce anxiety in older Latino adults with cancer and their caregivers. It involves sessions with both the patient and their caregiver to learn coping skills.
Basking Ridge, New JerseyAges 40 years+ - NCT06900452Recruiting
Pistachio breakfast and brain function in older adults
This study tests whether eating a pistachio-rich breakfast can improve memory and thinking in healthy older adults. If you qualify, you'll eat special breakfast meals and do some computer-based thinking tasks to measure how your brain performs.
Reading, BerkshireAges 65–80 - NCT06593925Recruiting
Snap-on denture made from a strong plastic for older adults
This trial tests a new plastic material (polyoxymethylene) to make a telescopic denture—a partial denture that snaps onto your remaining teeth. It is for people aged 65 and older who have lost several teeth but still have some healthy teeth to support the denture.
BelgradeAges 65–100 - NCT07582367Recruiting
How Foot Arches Affect Walking and Thinking in Older Adults
This study looks at whether the shape of your foot arches—how high or flat your arches are—affects how you walk and your thinking and memory skills. Researchers want to understand if foot structure plays a role in these abilities as we age.
Balıkesir, BigadiçAges 65 years+ - NCT06137339Recruiting
Daily avocado and cognition in older adults
This study tests whether eating one avocado daily for 6 months can help keep your thinking and memory sharp as you age. You must not currently eat many avocados or vegetables, and be willing to change your diet.
Kansas City, KansasAges 65–85 - NCT07258355Enrolling by invitation
Fall prevention program for older adults
This study is testing a program that combines everyday activities (like dressing or cooking) with other measures to reduce falls in older adults. If you're 65+, have fallen recently, and don't have certain health issues, this trial might help you stay safer at home.
AnkaraAges 65 years+ - NCT07623785Recruiting
Beef and Brain Health in Older Adults
This study looks at whether eating lean beef and dairy products daily affects brain health markers in people 65 and older. Researchers will track blood, urine, and other samples to see if beef consumption influences how your brain functions at the molecular level.
Brookings, South DakotaAges 65 years+ - NCT07369440Recruiting
Power training for fall risk in older adults
This study tests whether a community-based power training program can help reduce fall risk in older adults. It compares results for people who have fallen in the past year and those who haven't.
Maia, Porto DistrictAges 65 years+ - NCT07346989Recruiting
Brain stimulation to improve function in frail older adults
This study uses a gentle, non-invasive brain stimulation technique (called transcranial direct current stimulation, or tDCS) to see if it can improve physical function and daily activities in older adults who are showing early signs of frailty. You will be asked to do some simple exercises and cognitive tasks while receiving or not receiving the stimulation.
Valencia, ValenciaAges 65–90 - NCT07251543Enrolling by invitation
Salivary gland massage for dry mouth in older adults
This study tests whether a simple salivary gland massage program can help older adults with dry mouth improve chewing, swallowing, and overall oral health. It's designed for people aged 65 and older who can follow instructions and participate in activities.
Chiayi City, TaiwanAges 65 years+ - NCT07634406Recruiting
Phone-based frailty support program for older adults
This study tests whether nurses can help older adults stay strong and independent through regular phone calls and guidance. You'll receive support from a nurse over the telephone to manage weakness and prevent health decline.
Simav, KütahyaAges 65 years+ - NCT07391904Enrolling by invitation
Testing lab result communication for older adults
This study tests a tool designed to help older adults understand their lab results more easily. Researchers want to see if the tool improves patient understanding and engagement.
Los Angeles, CaliforniaAges 65 years+ - NCT05906511RecruitingEarly Phase 1
Study how THC levels change in older adults
This early study measures how a THC dose (by mouth or vaporized form) moves through the body and how it affects the body’s responses. It mainly looks at safety and how THC behaves in older adults, including people who have used cannabis before.
West Haven, ConnecticutAges 65 years+ - NCT05524597RecruitingPhase 1
Older adults write about health experiences
This study looks at how writing about your life experiences and health affects outcomes in older adults. If you’re 65 or older and meet health and safety requirements, you may be able to take part.
Los Angeles, CaliforniaAges 65 years+ - NCT05237687RecruitingPhase 2
Sirolimus to help prevent loss of daily function
This Phase 2 trial studies whether sirolimus can slow or prevent functional decline (more difficulty with daily activities) in older adults. You may be considered if you’re in the right age range and have no major heart, lung, liver, kidney, or recent bleeding/clotting problems.
Dallas, TexasAges 65–80 - NCT05421325RecruitingPhase 2
Vaccine-like immune treatment to prevent lung infections in seniors
This Phase 2 study tests a site-specific immune “booster” in people age 65 and older to help improve natural immunity and reduce respiratory (lung/airway) infections. You may be eligible if you can consent, are in an eligible living situation, and are not currently using certain immune-suppressing medicines.
Burnaby, British ColumbiaAges 65 years+ - NCT05461092RecruitingEarly Phase 1
Nerve blocks to improve pain control after spinal fusion
This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.
Iowa City, IowaAges 65 years+ - NCT05617027Recruiting
tDCS for long-term muscle and joint pain in older adults
This study tests whether a non-invasive brain stimulation treatment (tDCS) can reduce chronic muscle and joint pain in people age 65+. If you have pain for at least 6 months, this trial may help by targeting the brain signals involved in pain.
Montreal, QuebecAges 65 years+ - NCT05655403Recruiting
Step training for older adults with mild dementia
This trial studies whether a structured “step training” exercise program can help people with mild dementia move better or think more clearly. It may be helpful if you can walk independently and have a regular caregiver at home.
Hong KongAges 65 years+
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Common questions
- Are there clinical trials for older adults (65 years and older)?
- Yes. Clin2 currently lists 163 recruiting older adults (65 years and older) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a older adults (65 years and older) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a older adults (65 years and older) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.