Clinical trials · Pennsylvania
Oncology clinical trials in Pennsylvania
We’re tracking 112 recruiting oncology studies with a site in Pennsylvania — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT07091617Recruiting
Better genetic testing for young adults with cancer
This study tests a new way to offer genetic testing to young adults (ages 18-39) who have or had cancer. The goal is to make it easier for you to learn if you have inherited gene changes that could affect your cancer and your family's health.
Allentown, PennsylvaniaAges 18 years+ - NCT07059884Recruiting
Exercise program to help people with cancer stay active
This trial tests a distance-based exercise program designed to help people on chemotherapy maintain their physical function and prevent disability. It is for patients with certain cancers who are working full-time and can participate in moderate physical activity.
Butler, PennsylvaniaAges 18 years+ - NCT06805305RecruitingPhase 2
Immunotherapy for newly diagnosed glioblastoma
This trial tests a new personalized immunotherapy (DOC1021) for people with newly diagnosed glioblastoma. The treatment uses your own immune cells to attack the tumor and is given after surgery and with standard chemotherapy and radiation.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04804644RecruitingPhase 3
Memory-sparing radiation for brain metastases in small cell lung cancer
This study tests whether focusing high-dose radiation only on brain tumor spots, while avoiding the hippocampus (a brain area important for memory), helps protect memory and thinking compared with standard whole-brain radiation. It’s for people with small cell lung cancer that has spread to the brain.
Allentown, PennsylvaniaAges 18 years+ - NCT01790152Recruiting
Dexrazoxane study to monitor heart damage in cancer survivors
This study tests dexrazoxane (DRZ) to see how it affects blood and heart-related “biomarkers,” or measurable signs of heart damage, after cancer treatment. It mainly targets survivors who may be at risk for cardiomyopathy (heart muscle weakness) or related heart failure.
Philadelphia, PennsylvaniaAges Any age - NCT01577251Recruiting
Cancer patients on radiation can join a registry
This study builds a registry and blood/tissue sample collection for people who have cancer or a non-cancer growth (benign tumor) and are receiving radiation. It helps researchers learn from real-world treatment and biology, which may improve future care.
Lancaster, PennsylvaniaAges 18 years+ - NCT01000259Recruiting
Using stored tumor tissue after surgery for advanced ovarian cancer
This study looks at archived tumor tissue samples from people with advanced (stage III or IV) ovarian epithelial cancer who had surgery and standard “platinum/taxol” chemotherapy trials. It may help researchers understand the cancer better and improve future treatments.
Philadelphia, PennsylvaniaAges Any age - NCT02843945RecruitingPhase 1/Phase 2
Testing radiation for borderline pancreatic surgery using a tiny implant
This early trial studies whether adding targeted radiation during or around pancreatic surgery is safe and may improve outcomes for people with borderline resectable pancreatic cancer. It is mainly looking at feasibility and safety while treating close to the tumor but not spreading (no metastasis).
Philadelphia, PennsylvaniaAges 18 years+ - NCT02402244Recruiting
Caring registry study for children and young people with cancer
This study keeps a careful record of children, teens, and young adults with cancer (and some related growths) and may follow them over time. It helps researchers better track outcomes and future contact so care can improve.
Allentown, PennsylvaniaAges Up to 25 years - NCT02693535RecruitingPhase 2
Match FDA cancer drugs to a tumor gene change
This trial tests FDA-approved cancer medicines in people with advanced cancer whose tumor has a specific gene or protein abnormality. It tries to see whether targeting that tumor “fingerprint” can help when standard treatments no longer work.
Bethlehem, PennsylvaniaAges 12 years+ - NCT02701244Recruiting
Breast radiation microseed registry for certain early breast cancers
This registry study collects information about people with certain early breast cancer who receive a tiny radiation “microseed” placed in the breast after surgery. It may help doctors understand who benefits and how the treatment is done safely.
Pittsburgh, PennsylvaniaAges 50 years+ - NCT05720117RecruitingPhase 1
Study drug for advanced solid tumors with limited treatments left
This Phase 1 study tests PYX-201 in people with advanced (grown or spread) solid cancers to see if it is safe and how it works. You may qualify if your cancer has had up to a couple of prior treatments and you can safely take study medicines and undergo required testing like a tumor biopsy.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07501663Recruiting
Managing nerve damage from chemo in GI cancer survivors
This study tests different integrative approaches (like acupuncture or supplements) to help GI cancer survivors manage nerve damage from chemotherapy. You may be able to join if you have ongoing numbness and tingling from chemo.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07158450Enrolling by invitation
Heart health check for cancer patients
This trial tests a new device that monitors heart health during cancer treatment. It uses a simple on-body sensor alongside your regular echocardiogram to see if it can detect heart changes early.
Yardley, PennsylvaniaAges 18 years+ - NCT07078409Enrolling by invitation
Screening for ovarian cancer risk
This trial tests whether a nudge or reminder can help doctors refer patients with suspicious ovarian masses to a gynecologic oncologist. If you have a finding on an imaging test that suggests possible ovarian cancer, this study may help connect you with the right specialist.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06699615Enrolling by invitation
Assessing AI explanations by cancer doctors
This study asks lung cancer doctors at Penn Medicine to look at how an artificial intelligence tool explains its reasoning. The goal is to see if the explanations are clear and helpful for making treatment decisions.
Philadelphia, PennsylvaniaAges Any age
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting oncology studies listed above.
- University of Pennsylvania · 5 studies
- Lehigh Valley Hospital - Muhlenberg · 3 studies
- Lehigh Valley Hospital-Cedar Crest · 3 studies
- Allegheny General Hospital · 2 studies
- Fox Chase Cancer Center · 2 studies
- Geisinger Medical Center · 2 studies
- Lehigh Valley Hospital-Hazleton · 2 studies
- Pocono Medical Center · 2 studies
What taking part in a oncology study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Oncology trials in other states
Common questions
- Are there oncology clinical trials in Pennsylvania?
- Yes. We're currently tracking 112 recruiting oncology studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a oncology study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a oncology trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New oncology studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.