Targeted drug testing for advanced cancer with tumor gene changes
Treatments studied
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.
This trial tests whether FDA-approved targeted drugs can help people with advanced cancer whose tumors have specific gene changes. It aims to match your tumor's unique genetic profile to a drug that may work better for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 12 years or older (some drugs are only for adults)
- Have advanced cancer (solid tumor, multiple myeloma, or B-cell non-Hodgkin lymphoma) that has stopped responding to standard treatments or for which no standard treatment exists
- Be physically active and able to care for yourself (performance status 0-2)
- Have had a genomic test (tumor or blood) or a protein test on your tumor that shows a specific gene change that could be matched to a study drug
- Have acceptable organ function (kidneys, liver, blood counts) as determined by blood tests
- For oral drugs, be able to swallow pills and have no absorption problems
- Agree to use contraception if you or your partner can become pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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