Clinical trials
Ondansetron clinical trials
Below are recruiting ondansetron clinical trials, each written for real people, not researchers. We’re tracking 21 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07489742Recruiting
Ondansetron lozenge vs IV for shivering prevention in tonsillectomy
This trial tests whether an ondansetron lozenge works as well as IV ondansetron to prevent shivering after tonsillectomy in children. It could offer a needle-free way to reduce side effects during recovery.
Tanta, El-GharbiaAges 4–15 - NCT06810882Recruiting
Two ways to give nausea medicine for weight loss surgery
This study compares giving ondansetron (a nausea medicine) through a vein versus injecting it near a nerve to prevent nausea and vomiting after weight loss surgery. It may help identify which method works best for patients undergoing laparoscopic sleeve gastrectomy.
Tanta, Gharbia GovernorateAges 18–65 - NCT07511491Recruiting
Ondansetron lozenge vs IV for preventing shivering during C-section
This trial tests if an ondansetron lozenge (a tablet you dissolve in your mouth) works as well as ondansetron given through a vein to prevent shivering during cesarean section. Shivering is a common side effect of spinal anesthesia.
Tanta, El-GharbiaAges 18–40 - NCT06208917RecruitingPhase 3
Comparing two ways to give ondansetron for chemo nausea in kids
This trial compares two forms of ondansetron (a nausea medicine) — a dissolving film you put in the mouth versus a needle injection — to see which works better in preventing nausea and vomiting caused by chemotherapy in children with solid tumors.
Guangzhou, GuangdongAges 6 months–18 years - NCT07217600RecruitingPhase 4
Preventing vomiting during kids' radiation therapy
This trial tests a new, easy-to-take film that melts on the tongue to prevent vomiting caused by radiation therapy in children with cancer. It may be a good option if your child is getting radiation to the belly or spine and has trouble swallowing pills.
Chongqing, Chongqing MunicipalityAges 1–14 - NCT06080880Recruiting
Testing weekly vs every 3 weeks ondansetron for chemo nausea
This trial compares two schedules of ondansetron (a nausea prevention drug) in people getting cisplatin chemotherapy plus a PD-1 inhibitor. It aims to find which dosing schedule works best to prevent nausea and vomiting.
Wuhan, HubeiAges 18 years+ - NCT04150614RecruitingPhase 4
Granisetron skin patch versus ondansetron for transplant nausea
This study compares a granisetron skin patch to ondansetron tablets/medicine to see which works better to prevent nausea and vomiting around stem cell transplant. It may help your care team choose the most effective anti-nausea option for transplant patients.
Chicago, IllinoisAges 18–75 - NCT06850740Enrolling by invitation
Spinal ondansetron for hernia repair pain relief
This trial tests if adding ondansetron to standard spinal anesthesia during hernia surgery can provide better pain relief. It may help you need less pain medicine after the procedure.
IsmailiaAges 18–60 - NCT06930456Enrolling by invitation
Comparing two drugs to prevent low blood pressure during spinal anesthesia
This study tests if giving hydrocortisone (a type of steroid) or ondansetron (an anti-nausea drug) before spinal anesthesia can better prevent low blood pressure during surgery for your belly or lower leg.
Port Said, Port Said GovernorateAges 21 years+ - NCT06297499RecruitingPhase 1
Testing ondansetron to prevent itching after C-section
This trial tests if giving ondansetron before spinal anesthesia can prevent itching that often happens after a C-section. It may help you feel more comfortable during recovery.
Detroit, MichiganAges 18–50 - NCT07381634RecruitingPhase 2
Testing ondansetron to reduce immunotherapy side effects in liver cancer
This study tests whether adding ondansetron (a common anti-nausea drug) can reduce side effects from immunotherapy in people with liver cancer. If you are starting a specific combination treatment for liver cancer, you may be eligible.
Wenzhou, ZhejiangAges 18–80 - NCT03865290RecruitingPhase 2
Ondansetron for stomach nerve and motion problems in diabetes
This trial tests whether ondansetron can improve stomach “sensorimotor” problems—how the gut senses food and moves it—especially in people with diabetes and troubling indigestion. It may help reduce symptoms like early fullness, nausea, and discomfort after eating.
Rochester, MinnesotaAges 18–75 - NCT05755737RecruitingPhase 2
Ondansetron to prevent fainting episodes from vasovagal syncope
This Phase 2 study tests whether ondansetron can help prevent future fainting (vasovagal syncope) in adults who have had recent episodes. If it works, it may reduce how often you faint and improve safety in everyday situations.
Calgary, AlbertaAges 18–100 - NCT05844501RecruitingPhase 4
Ondansetron before heart ablation for atrial fibrillation
This trial tests whether ondansetron can help people with atrial fibrillation (an abnormal heart rhythm) around the time of elective catheter ablation. It may improve the safety or effectiveness of the procedure by targeting a pathway involved in heart rhythm events.
Indianapolis, IndianaAges 18–100 - NCT06861010RecruitingPhase 3
Ondansetron to prevent pancreatitis after ERCP
This trial tests whether ondansetron, a medicine that helps control nausea and vomiting, can reduce the risk of pancreatitis (inflammation of the pancreas) after an ERCP procedure. If you are scheduled for an ERCP and do not have certain health issues, you may be able to join.
TantaAges 18–65 - NCT07768124Recruiting
Acupoint patches for nausea in lung cancer chemo
This study tests whether acupoint patches can reduce nausea and vomiting caused by chemotherapy in people with lung cancer. Acupoints are specific spots on the body used in traditional Chinese medicine.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT03511118Recruiting
Drug safety study for breastfeeding mothers and babies
This study measures how common medicines move through a breastfeeding parent’s milk and checks safety in both the parent and breastfed baby. It may help doctors use these medicines more safely while you continue breastfeeding.
La Jolla, CaliforniaAges Any age - NCT05418244RecruitingPhase 2/Phase 3
Inhaled isopropyl alcohol for nausea and vomiting relief
This trial tests whether breathing in a small amount of isopropyl alcohol through the nose can reduce nausea or vomiting. It may help people who still have bothersome nausea even with usual care, by using a non-oral approach to start feeling better.
Buffalo, New YorkAges 7–17 - NCT06904235RecruitingPhase 2
A trial testing IV NEPA to prevent nausea and vomiting in kids getting strong chemo
This trial tests a medicine called IV NEPA (fosnetupitant/palonosetron) to prevent nausea and vomiting in children who are receiving strong chemotherapy. Patients will receive at least one cycle of chemotherapy that is highly likely to cause these side effects.
AthensAges birth–18 years - NCT06382012RecruitingPhase 2/Phase 3
Fosaprepitant for nausea in the emergency room
This study tests if a drug called fosaprepitant can help people in the emergency room whose nausea and vomiting don't improve with standard medicine. It may be an option if you still feel sick 2 hours after your first nausea treatment.
The Bronx, New YorkAges 18 years+ - NCT06656299Recruiting
Nerve block for gallbladder removal surgery
This study tests a nerve block called EOIB to see if it helps reduce pain after gallbladder removal surgery. If you are having planned gallbladder surgery, this might be a good option for you.
IstanbulAges 18–65
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Common questions
- Are there clinical trials for ondansetron?
- Yes. Clin2 currently lists 21 recruiting ondansetron studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ondansetron trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ondansetron trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.