Clinical trials
Optical Coherence Tomography clinical trials
Below are recruiting optical coherence tomography clinical trials, each written for real people, not researchers. We’re tracking 97 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07270133Recruiting
Diabetes eye health observation study
This study observes how diabetes affects vision over time in people with diabetes. It helps doctors better understand eye health without any treatment or intervention.
Augusta, GeorgiaAges 18 years+ - NCT06043622Recruiting
Healthy eye blood vessel database study
This study uses a special eye scan (OCT angiography) to create a reference database of normal blood vessels in healthy eyes. It helps doctors compare and diagnose eye conditions later.
AmiensAges 18 years+ - NCT06976034Recruiting
High-resolution eye camera study for eye conditions
This study uses a new type of eye camera to take very detailed pictures of the front of the eye (cornea, lens, and nearby areas). It is for people with certain eye conditions or for healthy volunteers.
ParisAges 18–80 - NCT03821467Recruiting
Eye scan study to test a new imaging method in healthy adults
This study checks whether a specific eye-scanning technology gives consistent, repeatable results. It enrolls healthy adults to see if the test works reliably before being used more broadly.
Vienna, State of ViennaAges 18–35 - NCT07625358Recruiting
How Caffeine and Alcohol Affect Your Eyes
This study measures how caffeine and alcohol change the size of your pupils (the dark circles in your eyes). Researchers want to understand how these common substances affect your eye's natural responses, which could help with vision and neurological research.
SingaporeAges 30–50 - NCT07720765Recruiting
Using eye scans to study brain diseases
This trial uses a type of eye scan (OCT) to look at the retina in people with brain conditions like multiple sclerosis, Alzheimer's, Parkinson's, or migraines. It aims to see if these scans can help doctors learn more about the disease and monitor it over time.
Milan, MilanoAges 18 years+ - NCT03401879Recruiting
Study eye blood-flow changes in multiple sclerosis
This study measures how blood flow in the eye changes in people with relapsing-remitting multiple sclerosis (RRMS) who previously had optic neuritis. The goal is to understand eye/brain blood-flow signals and how they may relate to MS.
Vienna, AustriaAges 18 years+ - NCT03711890Recruiting
Advanced imaging to detect early pancreatic cancer during surgery
This study tests a special high-resolution camera that can see tiny details during pancreatic surgery to help doctors detect early-stage pancreatic cancer or precancerous growths called IPMNs. The goal is to improve how well surgeons can identify and remove diseased tissue.
Columbus, OhioAges 18 years+ - NCT03870230Recruiting
Study of eye blood-flow signals in glaucoma and healthy eyes
This study compares eye blood-flow/brain-eye communication signals in people with glaucoma (or high eye pressure) versus people with normal eye tests. It may help researchers understand how glaucoma develops and progresses.
ViennaAges 18 years+ - NCT05068310Recruiting
Test a high-detail eye-like scan on skin tumors before biopsy
This study tests a high-resolution scan (called OCT) to better see skin tumors before they’re removed or biopsied. It may help doctors evaluate both non-pigmented and pigmented skin spots that look like possible skin cancer.
BerlinAges 18 years+ - NCT05171478Recruiting
Test imaging on small lung biopsy samples during bronchoscopy
This study uses a special eye-like scanning camera (full-field optical coherence tomography) to look at tiny lung tissue samples taken during routine bronchoscopy. It may help doctors learn more from small biopsies used to diagnose or stage lung problems.
Baltimore, MarylandAges 18 years+ - NCT05344274RecruitingPhase 4
Eye blood flow study in people with glaucoma
This study measures how blood flows in the retina and how well the eye regulates that flow. It compares people with early or very early glaucoma to people without glaucoma to see what differences may predict progression.
Baltimore, MarylandAges 18–88 - NCT05550077Recruiting
Imaging study for narrowed brain arteries after stroke
This trial uses a detailed eye/brain imaging test (optical coherence tomography) to study people with significantly narrowed brain arteries after certain stroke-like events. It may help researchers better understand and monitor this condition to improve care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05650905Recruiting
Eye and blood-vessel function study after COVID-19
This study measures how well the nerves in your retina and the tiny blood vessels in your eye “couple” (work together) after COVID-19. It may help researchers understand eye-related effects of COVID-19 and long COVID, and how these processes change over time.
Vienna, State of ViennaAges 18 years+ - NCT05728216Recruiting
Using a special eye-scan to study kidney biopsy samples
This study tests whether a noninvasive “eye-scan” during a kidney biopsy can help doctors tell the difference between acute kidney injury and chronic kidney disease. If it works, it may improve how kidney problems are diagnosed in routine practice.
Chalon-sur-Saône, Saône-et-LoireAges 18 years+ - NCT05856786Recruiting
Study how eye focusing surgery changes OCT measurements
This study looks at how refractive (vision-focusing) surgery affects OCT test images inside the eye. It may help doctors measure and track eye changes more accurately after surgery.
Omaha, NebraskaAges 19 years+ - NCT06321003Recruiting
Testing AI to detect early oral cancer with light scans
This trial uses a special light-based scanner (OCT) and artificial intelligence to help diagnose early signs of mouth cancer or precancer. It aims to see if this combination can make diagnosis easier and more accurate.
PalermoAges 18–99 - NCT06454370Recruiting
New imaging vs standard biopsy for Sjögren's diagnosis
This trial compares a new, quick imaging method (called full-field optical coherence tomography) with the standard lab analysis of a saliva gland biopsy. It may help diagnose Sjögren's syndrome faster and with less discomfort.
Mâcon, Sâone-et-LoireAges 18–99 - NCT06500728Recruiting
Vision involvement in giant cell arteritis
This study looks at how vision is affected in people with giant cell arteritis (GCA) -- a condition where blood vessels become inflamed. It compares those with GCA-related vision loss to people who have similar vision problems but not from GCA, to better understand and treat these eye issues.
Milan, LombardyAges 18 years+ - NCT06520904RecruitingPhase 4
PCSK9 inhibitor for coronary plaque in heart disease
This study tests whether a medication called a PCSK9 inhibitor (a type of drug that lowers bad cholesterol) can improve the buildup of plaque in heart arteries. It may be an option for people with coronary artery disease who have not been helped enough by statins alone.
Ürümqi, XinjiangAges 18–65 - NCT06679920Recruiting
New imaging probe to improve bladder cancer diagnosis
This trial tests a new optical probe that gives doctors a clearer view of bladder tumors during cystoscopy. It may help make diagnosis and treatment more accurate.
Amsterdam, North HollandAges 18 years+ - NCT06682819Recruiting
Looking at eye nerve layers in NOHL gene carriers
This study uses a special eye scan (OCT) to look at the layer of nerve fibers in the retina of people who carry (or don't carry) a specific gene change linked to Leber Hereditary Optic Neuropathy (NOHL). The goal is to find early warning signs in the blood that might show who is at risk of losing vision.
Paris, ParisAges 18–60 - NCT06687356Recruiting
Using OCT during lens surgery for better results
This study uses a special imaging technique called optical coherence tomography (OCT) during lens surgery to help doctors see inside your eye more clearly. It may be a good option if you need surgery for a cataract or a lens that is out of place.
Hangzhou, ZhejiangAges 18 years+ - NCT06736665Recruiting
Comparing two ways to treat hardened calcium in heart arteries
This trial compares two techniques (orbital atherectomy and intravascular lithotripsy) to break up tough calcium deposits in the heart's arteries that can block blood flow. If you have a calcified nodule and are having a non-emergency procedure to open a blocked artery, this study may help guide which method works best.
Alicante, AlicanteAges 18 years+
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Common questions
- Are there clinical trials for optical coherence tomography?
- Yes. Clin2 currently lists 97 recruiting optical coherence tomography studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a optical coherence tomography trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a optical coherence tomography trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.