Clinical trials
Optical Coherence Tomography clinical trials
Below are recruiting optical coherence tomography clinical trials, each written for real people, not researchers. We’re tracking 97 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03504800Recruiting
Using OCT scans to diagnose irregular corneas
This study tests whether a special eye scan called OCT can better identify causes of irregular cornea shape. Results may help doctors sort out different cornea problems so treatment choices, like certain procedures, can be more targeted.
Portland, OregonAges 14–85 - NCT03713268Recruiting
Using a scan to guide eye surgery in real time
This trial tests whether a special eye scan (OCT) can help guide eye surgery during the operation. It may improve how surgeons see and target the exact eye structures they need to treat.
Durham, North CarolinaAges 4 weeks+ - NCT03753256Recruiting
Testing a dental eye scan during orthodontic treatment
This study checks whether an optical coherence tomography scan—a quick, non-invasive imaging test—can help in dentistry for people who need orthodontic (braces/alignment) treatment. If you join, you’ll likely be scanned as part of the study and your dentist/doctor will compare results to see how useful the scan is.
HeidelbergAges 6 years+ - NCT03752840Recruiting
Community eye-worker program in Nepal
This trial tests a village-based approach to bring eye care closer to older community members. If you live in the right area and are willing to participate, it may help improve access to eye screening and services.
San Francisco, CaliforniaAges 60 years+ - NCT03761381Recruiting
Eye scan study for mild Alzheimer’s and memory changes
This study uses detailed eye imaging (an eye scan) to look for signs related to probable Alzheimer’s disease and mild dementia. It may help researchers understand whether eye scans can reflect brain changes and improve detection.
Portland, OregonAges 55 years+ - NCT04434586Recruiting
Imaging test to guide treatment of blocked thigh arteries
This study tests whether a detailed eye-like scan (optical coherence tomography) helps doctors choose better treatment for blockages in the thigh-to-knee artery. It may help improve healing and outcomes by guiding how the procedure is done.
LilleAges 18 years+ - NCT04505618Recruiting
Eye scan study using special imaging for blood-vessel disease
This study uses a detailed eye scan (optical coherence tomography angiography) to look at how blood vessels in the retina are affected. It may help researchers better understand retinal vascular diseases, though some people will be excluded for safety or image-quality reasons.
Baltimore, MarylandAges 18–99 - NCT07422688Enrolling by invitation
Using light scans to find heart artery blockages
This trial uses a special light-based scan (optical coherence tomography, or OCT) to help doctors see inside your heart arteries and find the exact blockage causing your heart attack. It may help guide treatment more precisely.
LeuvenAges 18 years+ - NCT05230446Recruiting
Testing full stent treatment for heart artery blockages
This study looks at how well doctors can treat multiple blocked heart arteries using a specific drug-eluting stent, aiming to fully open them. It may help patients whose blockage pattern fits the study, but it does not include certain high-risk or special cases.
Rotterdam, South HollandAges 18–85 - NCT05294978Recruiting
Testing a new light-based treatment for certain eye vision loss
This trial studies a light-guided eye treatment in people with generalized inherited retinal disease (a genetic cause of vision loss). It aims to see whether the approach works safely and can improve function for people whose vision is already significantly reduced.
San Francisco, CaliforniaAges Any age - NCT05335317Recruiting
Low-intensity laser for vaginal thinning and irritation
This trial studies whether a low-intensity nanosecond laser can improve vaginal atrophy (vaginal thinning) and related symptoms. It may help reduce discomfort for people who fit the study conditions and can complete the required visits and procedures.
Nizhny NovgorodAges 40–75 - NCT05558059Recruiting
Scan blood vessels in preemie babies’ eyes with special imaging
This study uses pictures to map the tiny blood vessels in an infant’s retina (the back of the eye). It may help researchers better understand how eye blood vessel growth happens in premature babies who need screening for ROP (retinopathy of prematurity).
Durham, North CarolinaAges Up to 2 months - NCT05859334RecruitingPhase 2
Erdafitinib for brain tumors that came back or worsened
This Phase 2 study tests erdafitinib, a targeted anti-cancer medicine, for certain brain cancers that have returned or progressed after standard treatment. It may help if your tumor has a specific genetic change (FGFR-TACC fusion) that this drug is designed to attack.
Aurora, ColoradoAges 18 years+ - NCT06074731Recruiting
Eye imaging study using a new scanner
This trial uses a special eye scanner to look at eye diseases. It might help doctors see eye problems more clearly.
Linz, Upper AustriaAges 5–110 - NCT06182683Recruiting
OCT-Guided vs. FFR-Guided Stent Placement in Heart Disease
This trial compares two imaging and pressure tests used during stent placement to see which helps improve blood flow better in people with chest pain or a recent heart attack.
SeoulAges 19 years+ - NCT06295471Recruiting
Comparing pain and healing after two laser treatments on thighs
This study compares two types of lasers (a new DFG laser and a standard CO2 laser) to see which one causes less pain and helps your skin heal better after a fractional laser treatment on your thighs. If you're looking to improve skin texture or reduce signs of aging, this might be an option.
Boston, MassachusettsAges 18 years+ - NCT06369766Recruiting
Eye scans to find retinal markers in neuroinflammatory diseases
This study uses advanced eye scans (OCT and retinal vessel imaging) to look for patterns in the retina that might be different in people with Multiple Sclerosis and other neuroinflammatory diseases. The goal is to find markers that could help doctors better understand and monitor these conditions.
BaselAges 18 years+ - NCT06431711Recruiting
Eye scan study for brain small vessel disease
This study uses a special eye scan (OCTA) to check the health of tiny blood vessels in the back of the eye. It may help doctors understand small vessel disease in the brain and find easier ways to monitor it.
Hangzhou, ZhejiangAges 35 years+ - NCT06460142Recruiting
Biomarker study for giant cell arteritis and polymyalgia rheumatica
This study is looking for biomarkers (biological clues) in people with newly diagnosed or flaring giant cell arteritis (GCA) or polymyalgia rheumatica (PMR). Participating may help researchers find better ways to diagnose and monitor these conditions.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT06606535Recruiting
Effects of hormone therapy on thinking skills in breast cancer
This study examines how certain hormone-lowering drugs (aromatase inhibitors) used after breast cancer treatment may affect memory, thinking, and concentration. It may help patients understand potential side effects on cognitive function.
Genova, GEAges 18 years+ - NCT06649305Recruiting
Study of vulnerable plaque in heart arteries of people with diabetes
This study uses a special camera (OCT and NIRS) inside heart arteries to look for dangerous plaque in people with diabetes. It may help doctors decide the best treatment to prevent heart attacks.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06758648Recruiting
Eye blood vessels in Fabry disease
This study looks at the tiny blood vessels in the eyes of people with Fabry disease using a special camera. It may help doctors understand how the disease affects the eyes over time.
München, BavariaAges 18 years+ - NCT06779110Recruiting
OCT vs. X-ray guidance for treating re-blocked stents
This study compares the standard X-ray guidance (angiography) with a more detailed imaging test (OCT) to guide treatment for a re-blocked stent. It aims to see which method leads to better outcomes for patients with in-stent renarrowing.
Aosta, AostaAges 18–99 - NCT06854198Recruiting
Glaucoma screening for at-risk Californians
This study tests whether offering eye exams at a health center helps find glaucoma early in people who are at higher risk. It may help you catch vision problems before they get worse.
Oakland, CaliforniaAges 50 years+
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Common questions
- Are there clinical trials for optical coherence tomography?
- Yes. Clin2 currently lists 97 recruiting optical coherence tomography studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a optical coherence tomography trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a optical coherence tomography trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.