Clinical trials
Oral Disease clinical trials
Below are recruiting oral disease clinical trials, each written for real people, not researchers. We’re tracking 192 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07069140Recruiting
Lactoferrin mouthwash for gum health during pregnancy
This study tests if a daily lactoferrin mouthwash can improve gum health in pregnant women with gum disease, without needing antibiotics or other treatments. Researchers want to see if this natural protein helps keep gums healthier during the second trimester.
Pavia, LombardyAges 18–45 - NCT06286501Recruiting
Preventive treatment for teens at risk of oral diseases
This trial tests a new preventive treatment for teenagers at risk of tooth decay and gum disease. It uses a special mouthpiece device (Lumoral) to clean teeth better and see if it can prevent oral health problems.
Tampere, PirkanmaaAges 14–16 - NCT06797778Enrolling by invitation
Oral health program for schoolchildren
This trial is a program to teach kids in Polígono Sur schools how to take care of their teeth and gums. It's a simple, no-risk way to learn about oral health.
Seville, SevillaAges Any age - NCT06319872RecruitingPhase 1
Study of disulfiram for vision in retinal degeneration
This trial tests whether disulfiram, a drug used for alcohol use disorder, can improve vision in people with retinal degeneration. You must have an alcohol use diagnosis and agree to avoid alcohol for 6 months.
Rochester, New YorkAges 18 years+ - NCT06979609RecruitingPhase 2/Phase 3
Preventing C. diff infection with vancomycin
This trial tests whether taking vancomycin by mouth can prevent another C. diff infection when you need to take other antibiotics. It’s for patients who recently had C. diff and are about to start a new antibiotic course.
Montreal, QuebecAges 18 years+ - NCT03429036Recruiting
Collecting head and neck tissue samples for research
This study collects tissue and fluid samples from people with head and neck disorders to help researchers learn more about these conditions. By donating leftover samples from your regular medical care, you can help advance research without extra procedures.
Washington D.C., District of ColumbiaAges 3–120 - NCT07142044RecruitingPhase 1/Phase 2
Testing EC5026 for Parkinson's disease
This study tests a new oral medication called EC5026 for Parkinson's disease. It aims to see if the drug is safe and if it might help control symptoms when added to your current levodopa treatment.
Sacramento, CaliforniaAges 50–80 - NCT05997043RecruitingEarly Phase 1
Botulinum toxin for overactive bladder in Parkinson's disease
This trial tests if botulinum toxin A injections can help control overactive bladder symptoms in people with Parkinson's disease who haven't gotten enough relief from standard bladder medications. It aims to see if the treatment is safe and effective.
Guangzhou, GuangdongAges 25–80 - NCT07703137Enrolling by invitation
NAD Supplement for Parkinson's Disease Study
This study tests whether a supplement called NAD (a natural substance that helps cells produce energy) can improve symptoms in people with Parkinson's disease. You would take the supplement daily for several weeks, and researchers will check your movement, thinking, and overall well-being.
Oklahoma City, OklahomaAges 55–85 - NCT06863155Recruiting
A thin heart stent for people on blood thinners
This trial tests a new type of heart stent in people who also take daily blood thinners. The stent is very thin and releases medicine over time to help keep the artery open, and the coating eventually dissolves. It may be a safer option for people on blood thinners who need a stent.
AlbaceteAges 18 years+ - NCT04262206RecruitingPhase 4
Testing how statins affect outcomes in adults 75 and older
This trial studies whether cholesterol-lowering medicine (a statin, specifically atorvastatin) improves health and benefits in people age 75 and older in everyday life. It may help doctors understand which older adults benefit most and how to use these medicines safely.
Birmingham, AlabamaAges 75 years+ - NCT00977977RecruitingPhase 2
Rituximab plus cyclosporine for membranous kidney disease
This trial tests whether rituximab (an immune-targeting medicine) plus cyclosporine (another immune medicine) can better control protein leakage in the urine for people with idiopathic membranous nephropathy. It may help reduce long-lasting kidney damage risk when standard treatments like ACE inhibitor or ARB don’t control the protein level.
Bethesda, MarylandAges 18–90 - NCT06315855Recruiting
Oral Health Program for Cancer Survivors
This study tests a program to help cancer survivors improve their oral health using a smartphone app. It's for survivors who are at least 6 months past treatment and have not had head, neck, or mouth cancer.
Washington D.C., District of ColumbiaAges 25–75 - NCT07530978Recruiting
Oral Health, Gum Disease, and Quality of Life Study
This study looks at how gum health affects daily life and quality of living. Researchers want to understand the connection between oral hygiene habits, gum disease status, and how patients feel overall.
Bolu, BoluAges Any age - NCT06000761Recruiting
Mouth care with human milk for premature babies
This trial is testing whether giving gentle mouth care with human milk to very premature babies in the NICU can help their health. It focuses on babies born early and with low birth weight whose mothers can provide milk.
Gainesville, FloridaAges 1 hour–3 days - NCT07519057Recruiting
Carbohydrate drink before liver transplant surgery
This study tests whether drinking a carbohydrate solution before planned liver transplant surgery helps patients recover better afterward. Researchers believe it may reduce complications and improve healing.
WarsawAges 18 years+ - NCT05463796Recruiting
Prevention and early detection for people at high cancer risk
This study looks at surveillance (watching closely), prevention, and early “interception” steps to lower the chance that cancer will develop or be found later. It is for people with genetic risk, past cancer treatment exposures, strong family history, or certain early pre-cancer or high-risk conditions.
Boston, MassachusettsAges Any age - NCT05242315RecruitingPhase 4
Long-acting tacrolimus after liver transplant
This trial studies whether taking an extended-release form of tacrolimus (a medicine to prevent transplant rejection) after a liver transplant works well for people who are followed at the University of Alberta. It may help simplify dosing and monitor safety and effectiveness after transplant.
Edmonton, AlbertaAges 18 years+ - NCT06870630Recruiting
Comparing two myotomy methods for type 2 achalasia
This trial tests two muscle-cutting procedures for people newly diagnosed with type 2 achalasia (a swallowing disorder). The goal is to see if a more complex myotomy works better than the standard one.
Hyderabad, TelanganaAges 18–75 - NCT07559942Recruiting
Apiban to Help Dialysis Fistulas Mature Successfully
This trial tests whether a blood-thinner medication called apixaban (Apiban) helps arteriovenous fistulas—surgically created connections in the arm for dialysis—develop and work better. If it helps fistulas mature faster and more reliably, it could reduce complications and improve treatment for kidney failure patients.
Lahore, Punjab ProvinceAges 18 years+ - NCT06890676Recruiting
Dental care in nursing homes to prevent infections and improve health
This study tests whether bringing dental care to nursing home residents can reduce mouth infections, pneumonia, and help control blood sugar in people with diabetes. If you live in a nursing home and are 60 or older, you may be able to join.
Jefferson City, MissouriAges 60–100 - NCT06003153RecruitingPhase 4
Gene and sugar response study with oral semaglutide
This study looks at how your genes affect your body's response to a diabetes medication called semaglutide. It may help people with slightly high blood sugar (pre-diabetes) understand why some respond better than others.
Boston, MassachusettsAges 18–65 - NCT05643651RecruitingPhase 4
Rivaroxaban for kids with large heart artery aneurysms after Kawasaki disease
This trial studies whether rivaroxaban (a blood thinner) can help prevent dangerous clots in children age 2 and older who have “giant” coronary artery aneurysms after Kawasaki disease. Doctors will see if it’s safe and tolerable for children who are also on standard anti-clot/anti-platelet medications for the next 3 months.
Shanghai, Shanghai MunicipalityAges 2–18 - NCT07167875Enrolling by invitation
Digital coaching trial to improve toothbrushing habits
This study tests if personalized coaching through a smartphone app helps people stick to better toothbrushing habits. Participants use an electric toothbrush and app for 19 weeks to see if coaching improves oral hygiene.
Petaluma, CaliforniaAges 18–80
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Common questions
- Are there clinical trials for oral disease?
- Yes. Clin2 currently lists 192 recruiting oral disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oral disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oral disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.