Clinical trials
Oral Health clinical trials
Below are recruiting oral health clinical trials, each written for real people, not researchers. We’re tracking 172 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06370000RecruitingPhase 4
Oral azacitidine for AML patients with health disparities
This trial tests an oral medication (azacitidine) for people with AML who are in remission and planning a stem cell transplant. It focuses on patients who face health disparities, such as financial or access barriers, to help make transplant more successful for everyone.
Richmond, VirginiaAges 18 years+ - NCT06016465RecruitingEarly Phase 1
Nerve block plus steroid to prevent migraine return in 72 hours
This trial tests whether adding a steroid pill (dexamethasone) to a nerve block can stop a migraine from coming back within three days. It's for people whose headache got much better after a nerve block.
El Paso, TexasAges 18–85 - NCT06912048Recruiting
How nerves signal the body in health and overweight
This study looks at how your brain sends signals to your body, comparing healthy people and those who are overweight. You'll help researchers understand differences in nerve communication.
UlmAges 18 years+ - NCT06706752Recruiting
Shengbai oral formula for chemotherapy side effects
This study tests if a Chinese herbal formula called Shengbai can safely reduce side effects from chemotherapy. It might help you feel better during cancer treatment.
Oakland, CaliforniaAges 18–80 - NCT07285785RecruitingPhase 4
Rifaximin for children with acute diarrhea
This study tests whether a medicine called rifaximin, taken along with oral rehydration solution, helps children aged 6 to 11 recover faster from acute (short-lasting) diarrhea that is likely caused by a bacterial infection. The study compares rifaximin plus oral rehydration versus oral rehydration alone.
Lynwood, CaliforniaAges 6–12 - NCT07740824Recruiting
Oral supplement for healthier, younger-looking skin
This study tests an oral supplement to see if it improves signs of facial skin aging in healthy adults. Participants take the supplement daily for 8 weeks and undergo two small skin biopsies on the upper arms to measure changes.
Bangalore, KarnatakaAges 35–65 - NCT07142044RecruitingPhase 1/Phase 2
Testing EC5026 for Parkinson's disease
This study tests a new oral medication called EC5026 for Parkinson's disease. It aims to see if the drug is safe and if it might help control symptoms when added to your current levodopa treatment.
Sacramento, CaliforniaAges 50–80 - NCT07101250RecruitingPhase 4
Study of acetazolamide before laparoscopic hysterectomy
This trial tests a medication called acetazolamide given before surgery to see if it can help prevent shoulder pain after a laparoscopic hysterectomy. If you are a woman scheduled for this type of hysterectomy, you may be able to join.
Greenville, South CarolinaAges 21–65 - NCT03934905RecruitingPhase 1/Phase 2
Sulforaphane supplement to protect the heart during doxorubicin
This trial tests whether a nutritional supplement called sulforaphane (SFN) can help protect heart function in people with breast cancer who are receiving doxorubicin (a chemotherapy that can affect the heart). Participants take caplets and have heart and safety monitoring to see if the supplement reduces heart-related side effects.
Lubbock, TexasAges 18–89 - NCT06229678RecruitingEarly Phase 1
Ketones and diabetes drug for heart failure with weak pump
This clinical trial looks at whether adding a special diet supplement (ketones) to an SGLT2 inhibitor diabetes drug improves heart function and symptoms in people who have both type 2 diabetes and heart failure with a weakened heart muscle.
San Antonio, TexasAges 18–70 - NCT06315881RecruitingPhase 2
Study of Nicotine Pouches for Cigarette or Snuff Users
This trial tests nicotine pouches (like small pouches you put in your mouth) as a way to help people who smoke cigarettes or use moist snuff. It studies how your body reacts to these pouches under controlled conditions and during daily life.
Columbus, OhioAges 21 years+ - NCT06979609RecruitingPhase 2/Phase 3
Preventing C. diff infection with vancomycin
This trial tests whether taking vancomycin by mouth can prevent another C. diff infection when you need to take other antibiotics. It’s for patients who recently had C. diff and are about to start a new antibiotic course.
Montreal, QuebecAges 18 years+ - NCT06683521Recruiting
Understanding the immune system in FPIES
This study looks at how the immune system works in people with Food Protein-Induced Enterocolitis Syndrome (FPIES). It aims to learn more about this condition to improve future diagnosis and treatment.
New York, New YorkAges 1–60 - NCT07122128Recruiting
Saliva test for early oral cancer in people with OSMF
This trial studies whether a simple saliva test can help detect oral cancer early in people who have a condition called oral submucous fibrosis (OSMF), which raises the risk of oral cancer. Healthy volunteers and those with OSMF or proven oral cancer are needed.
Jāmshoro, SinchAges Any age - NCT07242326Enrolling by invitation
Blood Thinner Dose Check for Older Adults With AFib
This study looks at whether older adults with atrial fibrillation are taking the right dose of their blood thinner medicine. It aims to improve how doctors prescribe these medications in primary care.
Ordu, OrduAges 65 years+ - NCT04220749RecruitingPhase 2
Radiation vs mouth surgery for HPV-negative throat cancer
This Phase 2 trial compares two standard cancer treatments—radiation or surgery through the mouth—for HPV-negative oropharyngeal throat cancer. It aims to find out which approach works better while keeping side effects and quality of life acceptable.
London, OntarioAges 18 years+ - NCT07857655RecruitingPhase 4
Intraoperative methadone for pain after head and neck cancer surgery
This trial tests whether giving methadone during your head and neck cancer surgery helps control pain right after the operation. Methadone is a long-acting painkiller that might reduce pain for up to a day or more, potentially improving your recovery experience.
Portland, OregonAges 18–89 - NCT05309460RecruitingPhase 4
Labetalol or nifedipine to treat postpartum high blood pressure
This study compares two common blood pressure medicines—labetalol and nifedipine—to control high blood pressure after childbirth. It may help you and your care team find the safest way to bring your blood pressure back to normal after delivery.
Omaha, NebraskaAges 19 years+ - NCT07845825RecruitingEarly Phase 1
Aprepitant for CLIFAHDD syndrome
This trial tests a drug called aprepitant to see if it can help people with CLIFAHDD, a rare genetic condition that affects movement and development. The study will check if the drug is safe and if it improves symptoms.
San Antonio, TexasAges 6 months+ - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70 - NCT07626606Recruiting
Gut Health and Rotavirus Vaccine Response in Adults
This study examines how the health of your digestive system affects how well your body responds to an oral rotavirus vaccine (a vaccine given by mouth to protect against rotavirus infection). You'll have two endoscopy procedures—a camera test to look inside your digestive tract—and provide samples to help researchers understand this connection.
Lusaka, Lusaka ProvinceAges 18–50 - NCT04774159RecruitingPhase 3
Low-dose colchicine to lower risk in leg artery disease
This trial tests whether low-dose colchicine can reduce “residual” risk—future heart and blood-vessel problems—in people with peripheral artery disease (PAD). It targets PAD symptoms and complications like poor blood flow in the legs, even after certain procedures.
New Haven, ConnecticutAges 18 years+ - NCT07727642Recruiting
Optimizing HIV Medicines for AIDS-Related Lymphoma
This trial helps doctors find the best way to combine HIV medicines (antiretroviral therapy) with lymphoma treatment for people who have both HIV and AIDS-related lymphoma. The goal is to improve your overall care and outcomes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06148025RecruitingPhase 4
Antibiotics and vaccine response study
This study looks at whether taking a short course of antibiotics changes how well vaccines work. You would receive the BCG vaccine (for tuberculosis) and possibly the yellow fever vaccine, and we would check your immune response over several months.
Adelaide, South AustraliaAges 18–35
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Common questions
- Are there clinical trials for oral health?
- Yes. Clin2 currently lists 172 recruiting oral health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oral health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oral health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.