Clinical trials
Oral Health clinical trials
Below are recruiting oral health clinical trials, each written for real people, not researchers. We’re tracking 172 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05444127Recruiting
Study of oral health in people with Wilson’s disease
This study compares oral (mouth and teeth) health in people with Wilson’s disease versus people without it. It aims to see whether Wilson’s disease is linked to specific dental and imaging findings, which could help with future prevention and care.
Ivry-sur-SeineAges 18 years+ - NCT07143201RecruitingPhase 2
Precision dosing of ibuprofen for PDA in premature babies
This study tests a personalized way to give ibuprofen to very premature babies with a heart condition called PDA. It aims to see if adjusting the dose can help close the heart opening more safely.
Hamilton, OntarioAges Up to 6 months - NCT07591818Recruiting
How menstrual cycles affect athletic performance and health
This study examines how your menstrual cycle (or birth control pill) affects your athletic performance, health, and body. Researchers will compare female athletes with natural cycles to those using oral contraceptives to understand these differences better.
Cruz Quebrada, OeirasAges 18–30 - NCT07069140Recruiting
Lactoferrin mouthwash for gum health during pregnancy
This study tests if a daily lactoferrin mouthwash can improve gum health in pregnant women with gum disease, without needing antibiotics or other treatments. Researchers want to see if this natural protein helps keep gums healthier during the second trimester.
Pavia, LombardyAges 18–45 - NCT06438471RecruitingPhase 1
Study of a new drug for nerve pain after spinal cord injury
This trial tests an experimental pill for people with spinal cord injury who have long-term nerve pain. It aims to see if the drug can reduce pain and be safe.
Augusta, GeorgiaAges 18 years+ - NCT05425355RecruitingPhase 4
IV versus oral acetaminophen after hip-fracture surgery
This trial compares giving acetaminophen (Tylenol) through a vein versus by mouth after hip-fracture surgery. It may help find which method works better for pain control and recovery in adults.
Toronto, OntarioAges 60 years+ - NCT06697574Enrolling by invitation
Hypnotherapy for oral lichen planus
This trial tests whether hypnosis can help manage oral lichen planus (OLP), a chronic mouth condition. You will be randomly assigned to either hypnotherapy or a session explaining how your mind and immune system interact. Your symptoms will be checked after 2, 6, and 12 weeks.
Tel AvivAges 18 years+ - NCT07557277Recruiting
Gum Recession and Quality of Life Study
This study looks at how gum recession (when gums pull back from teeth) affects your quality of life and oral health. Researchers will ask you questions and examine your teeth to understand this connection better.
Rohtak, HaryanaAges 18–45 - NCT06984848Recruiting
Mouth spray for dry mouth in older adults
This trial tests an enzyme-containing mouth spray (Oral7®) to see if it helps with dry mouth, improves saliva flow, and boosts quality of life for older adults. If you often have a dry mouth, this spray might offer relief.
Kubang Kerian, KelantanAges 60 years+ - NCT06576063Recruiting
Light therapy for better oral hygiene in older adults
This study tests a special light therapy (called antibacterial photodynamic therapy) used with a device called Lumoral to improve oral hygiene in older adults. It may help reduce bacteria and plaque in people who can brush their teeth and follow the study routine.
Loviisa, UusimaaAges 65 years+ - NCT06085781Recruiting
MRI and tumor study for head and neck cancer patients
This trial uses special MRI scans to look at your head, neck, and tumor environment before treatment. It aims to find better ways to understand your cancer and guide care.
Toronto, OntarioAges 18 years+ - NCT07694544RecruitingPhase 1
Oral EC5026 study in people with kidney disease
This trial tests a medication called EC5026 in people with and without chronic kidney disease (CKD) to see how the body handles it. It helps understand if dose adjustments are needed for people with impaired kidney function.
Sacramento, CaliforniaAges 55 years+ - NCT07503925RecruitingPhase 4
THRIVE Study: Oral nicotine pouches and health
This study looks at how oral nicotine pouches (a type of smokeless tobacco product) affect health. If you use these pouches daily and meet a few other conditions, you may help researchers understand their public health impact.
Columbus, OhioAges 21 years+ - NCT06256146Recruiting
Treating food allergies with modified oral immunotherapy
This study tests a new approach to oral immunotherapy for food allergies, aiming to make it safer and more effective. It's for people who have had a clear allergic reaction to a food and have a positive allergy test.
Montreal, QuebecAges 2–40 - NCT06259006RecruitingPhase 3
Early Dexamethasone for Sydenham's Chorea in Children
This trial tests whether a short course of dexamethasone (a steroid tablet) can help children with Sydenham's chorea (movement tics after a strep infection) recover faster. The goal is to see if early treatment improves symptoms and reduces side effects compared to other treatments.
Darwin, Northern TerritoriesAges 4–17 - NCT07209527Enrolling by invitationEarly Phase 1
Truway diagnostic tools in primary care
This trial tests new diagnostic tools that doctors can use in primary care. Researchers want to see if these tools help find the right diagnosis faster and more accurately.
New York, New YorkAges Any age - NCT06038019Recruiting
Food allergy threshold test and prediction study
This study looks at people with suspected or known food allergies to find out how much of a food it takes to cause a reaction. It uses an oral food challenge (eating the food under medical supervision) to predict your personal threshold.
Hamilton, OntarioAges 3 months–65 years - NCT07405554RecruitingPhase 2
Zinc with botox for overactive bladder
This trial tests whether taking zinc along with a botox injection (a standard treatment) can better reduce sudden, strong urges to urinate in women with overactive bladder who haven't gotten relief from other treatments.
Skokie, IllinoisAges 21–100 - NCT07228702Enrolling by invitationPhase 1
Bacteriophage therapy for one patient with lung infection
This is a special program for one patient with a lung infection from Mycobacterium abscessus. The trial uses a treatment with bacteriophages, which are viruses that attack specific bacteria.
Vancouver, British ColumbiaAges Any age - NCT06953479RecruitingPhase 4
Hepatitis C treatment for people awaiting trial in jail
This study offers a once-daily pill (Epclusa) to treat hepatitis C for people in jail who have never taken HCV medicine before. The goal is to see if starting treatment while incarcerated and continuing after release can cure the infection.
Cranston, Rhode IslandAges 18 years+ - NCT05470023Recruiting
Imaging study of gum health and mouth biofilm
This study uses imaging to look at how healthy your gums are and how much “plaque/biofilm” is in your mouth. It may help researchers better understand gum health and how oral hygiene affects it.
Irvine, CaliforniaAges 18 years+ - NCT03968393RecruitingPhase 4
Blood thinner to prevent stroke after stress-related irregular heartbeats
This trial tests whether taking a blood thinner can lower the risk of stroke in people who had atrial fibrillation (an irregular heartbeat) that happened temporarily around a stressful illness or surgery. It looks especially at people at higher risk for stroke after that episode.
Los Angeles, CaliforniaAges 55 years+ - NCT03932903Recruiting
Phone coaching to help teens stay on leukemia medicine
This trial tests a mobile (phone) health program to help adolescents and young adults with leukemia take their oral chemotherapy medicine consistently. It may help if staying on daily pills is hard during the maintenance phase of treatment.
Chicago, IllinoisAges 14 years+ - NCT06890676Recruiting
Dental care in nursing homes to prevent infections and improve health
This study tests whether bringing dental care to nursing home residents can reduce mouth infections, pneumonia, and help control blood sugar in people with diabetes. If you live in a nursing home and are 60 or older, you may be able to join.
Jefferson City, MissouriAges 60–100
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Common questions
- Are there clinical trials for oral health?
- Yes. Clin2 currently lists 172 recruiting oral health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oral health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oral health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.