Clinical trials
Oral Health clinical trials
Below are recruiting oral health clinical trials, each written for real people, not researchers. We’re tracking 172 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07014137RecruitingPhase 2
A study of an oral pill for angiogenic sarcomas
This trial tests an oral medication (ABSK043) that may help your immune system fight certain rare sarcomas. It is for people with intimal sarcoma, head and neck angiosarcoma, or epithelioid hemangioendothelioma that has spread or cannot be removed by surgery.
Toronto, OntarioAges 18 years+ - NCT07245732RecruitingPhase 4
Steroid pills vs. shots for rheumatoid arthritis flares
This trial compares steroid pills to steroid shots for controlling sudden worsening of rheumatoid arthritis symptoms. It aims to find which method works better and is easier for you.
Toronto, OntarioAges 18 years+ - NCT05266898RecruitingPhase 4
HPV vaccine response study for people living with HIV
This trial studies how well the Gardasil-9 HPV vaccine triggers the body’s immune response in people living with HIV. It may help doctors understand the best way to protect against HPV-related cancers and infections in this population.
New Orleans, LouisianaAges 18–65 - NCT06859866Recruiting
Light therapy for gum disease around dental implants
This trial tests whether a special light treatment (photodynamic therapy) you can use at home can help reduce inflammation around dental implants (peri-implant mucositis). It's designed for people with early gum problems around implants, before they get worse.
RomaAges 18 years+ - NCT06017817Recruiting
Light therapy for implant gum disease
This study tests a special light-activated treatment (antibacterial photodynamic therapy) to fight infection around dental implants. It may be an option for people with moderate to severe implant-related gum disease who are not smokers and do not have diabetes.
StockholmAges 18–85 - NCT07346092Recruiting
Health beliefs and social behaviors about nicotine pouches
This study looks at how graduate students at Ohio State University perceive and use oral nicotine pouches. The goal is to create better ways to communicate the addictive risks of these products.
Columbus, OhioAges 21 years+ - NCT06713733Recruiting
Steroid injection vs. pill for wisdom tooth recovery
This trial compares two treatments—a steroid placed under the gum and a pill—to reduce pain, swelling, and other problems after removing a lower wisdom tooth. It is for generally healthy patients who need that surgery and haven't taken anti-inflammatory drugs recently.
Dharān, KoshiAges 18 years+ - NCT07667088Recruiting
Whitening mouthwash using oil pulling
This study tests a whitening mouthwash that uses an oil-pulling method. It lasts a few months and compares the mouthwash to not using any whitening product. If you have naturally darker front teeth and haven't whitened them recently, this might be an option for you.
San Antonio, TexasAges 18–60 - NCT04284839RecruitingPhase 3
Blood thinner pills vs warfarin after heart surgery
This trial compares two ways to prevent blood clots after open heart surgery: a “direct oral” blood thinner pill versus warfarin (a vitamin K antagonist). It may help find the safest and most effective option for people who develop atrial fibrillation after surgery.
Fitzroy, VictoriaAges 18 years+ - NCT01365169Recruiting
How activity level and daily function relate to cancer survival
This study looks at how physical activity (movement during the day) and a clinician-rated “day-to-day function” score relate to overall survival in people with certain cancers. It may help doctors understand who benefits most from activity-focused care and better monitoring.
Houston, TexasAges 18 years+ - NCT03511846Enrolling by invitationPhase 1
Pain biomarker study for headache or back nerve pain
This study looks at measurable “pain signals” (biomarkers) in people with certain headache disorders or lumbar nerve pain, and compares them with healthy people. It may help researchers better understand what drives pain and how it can be detected.
Houston, TexasAges 18 years+ - NCT06807736Recruiting
Choosing injectable PrEP for HIV prevention in Cape Town
This study offers three ways to prevent HIV: a shot every two months (injectable PrEP), daily pills, or a vaginal ring. Researchers in Cape Town will help you choose the option that fits your life best.
Cape Town, Western ProvinceAges 15 years+ - NCT07246161RecruitingPhase 2
Tracking probiotics from mouth to vagina in healthy women
This study tests whether probiotic bacteria taken by mouth can be found in the vagina of healthy women. It involves taking a daily probiotic for 4 weeks and providing samples (stool, vaginal swabs, and skin swabs) to track where the probiotics go.
MontrealAges 18–50 - NCT04055428RecruitingPhase 2
Testing a hormone supplement to improve heart and metabolic health
This study tests whether adding a natriuretic peptide medicine improves heart health and metabolism in Black adults. It may help with blood pressure and related health markers, but you must meet specific health and safety criteria.
Birmingham, AlabamaAges 18 years+ - NCT00260585Recruiting
Esophageal risk and tissue registry study
This study collects information and, if you already need blood tests or procedures, may take extra small tissue samples (biopsies) to better understand esophageal-related conditions. It may help researchers learn about risk and future management for people with certain esophagus or reflux-related diagnoses.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06084520Recruiting
Pain questionnaire study for opioid and non-opioid patients
This study tests two questionnaires for people with long-term pain. Researchers want to see if the tools work well for both those taking opioids and those who are not. Your answers can help improve pain care.
Uppsala, UpplandAges 18–75 - NCT06108076RecruitingEarly Phase 1
Oral ketones for heart failure and diabetes
This study tests whether taking a special oral ketone supplement can help people with both heart failure and diabetes. It looks at both short-term and long-term effects on heart function and blood sugar control.
San Antonio, TexasAges 18–80 - NCT07561541RecruitingPhase 4
Extended Antibiotics for Diabetic Leg Fracture Surgery
This study tests whether taking antibiotics for a longer time helps prevent infections in people with poorly controlled diabetes who need surgery for a lower leg or foot fracture. Since diabetes makes infections more likely after surgery, extra antibiotics might reduce that risk.
Los Angeles, CaliforniaAges 18 years+ - NCT07476339RecruitingPhase 4
Returning to HIV Care with Biktarvy
This trial tests the medication Biktarvy (bictegravir, emtricitabine, and tenofovir alafenamide) for people with HIV who have stopped taking their antiretroviral therapy (ART) for at least 12 weeks and are ready to restart treatment. It aims to see how well the medication works when restarting care.
Clearwater, FloridaAges 18 years+ - NCT06714526Recruiting
Gene test to pick best anti-clot drug for narrowed brain arteries
This trial compares using a genetic test to choose between two anti-clot medications (clopidogrel and ticagrelor) versus the usual approach of giving clopidogrel alone. It aims to see if personalized treatment can better prevent strokes in people with narrowed brain arteries.
Calgary, AlbertaAges 40 years+ - NCT04373473RecruitingPhase 2
Oral stool treatment to prevent ulcerative colitis flare-ups
This study tests whether taking freeze-dried (lyophilized) donor stool material by mouth can help prevent ulcerative colitis from coming back or causing intestinal inflammation. Participants are in remission and stay on their usual treatment while receiving the study product.
Houston, TexasAges 18 years+ - NCT04829136Recruiting
Fiber supplement for blood cancer treatment
This trial tests whether taking a daily fiber supplement can help people undergoing treatment for blood cancers. It aims to improve gut health and possibly reduce treatment side effects.
Seattle, WashingtonAges 18 years+ - NCT03213002RecruitingPhase 1/Phase 2
CAPTEM pills after brain radiation for newly diagnosed glioblastoma
This trial studies whether taking two chemotherapy pills (capecitabine and temozolomide) after the initial 6-week radiation-and-chemo phase can help people with newly diagnosed glioblastoma. It aims to test safety and early effectiveness right before the usual maintenance temozolomide phase.
New York, New YorkAges 18–74 - NCT06603662RecruitingPhase 4
Steroids for sudden osteoarthritis pain in the emergency room
This trial tests if a short course of oral steroids (glucocorticoids) can relieve sudden osteoarthritis pain in the knee, hip, or shoulder for people who come to the emergency department and are well enough to go home.
York, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for oral health?
- Yes. Clin2 currently lists 172 recruiting oral health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oral health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oral health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.