Clinical trials
Osteoarthritis clinical trials
Below are recruiting osteoarthritis clinical trials, each written for real people, not researchers. We’re tracking 592 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07875296Recruiting
Enzyme levels in knee arthritis
This study looks at certain enzymes in the blood of women with knee osteoarthritis. It may help doctors understand how arthritis works and could lead to better treatments.
AfyonkarahisarAges 40–70 - NCT03949400Recruiting
Exercise therapy and a soft knee brace for knee arthritis
This study tests whether an exercise program plus education, along with a soft brace, helps improve symptoms and function in adults with knee osteoarthritis. It may help people who have knee pain by combining movement training with daily support.
Aalborg, NothernAges 18 years+ - NCT04260165Recruiting
Wrist surgery options for certain wrist arthritis
This trial compares two types of wrist surgery for osteoarthritis in the wrist bones (SLAC/SNAC stage II–III). It may help you and your surgeon choose the procedure that best improves pain and wrist function for your specific wrist arthritis pattern.
HelsinkiAges 18–75 - NCT04960098Recruiting
Survey after hip or knee replacement surgery
This study asks people who have had a hip or knee replacement to share how they’re doing over time. It’s testing whether patient-reported survey answers can help measure recovery and outcomes.
MilanAges 18 years+ - NCT05127005Recruiting
Compare thumb arthritis surgery versus placebo surgery
This study compares a real thumb basal joint surgery (trapeziectomy) with a sham/placebo operation to see which option helps pain and daily function better. It is for people with thumb arthritis who have tried non-surgical treatments but still have significant thumb pain.
HelsinkiAges 45 years+ - NCT04247672Recruiting
Study of knee replacement outcomes using a specific knee implant
This study follows people who need knee replacement for “end-stage” knee osteoarthritis and will receive a specific knee implant system as part of routine care. It aims to measure how well the knee replacement works for patients over time, which may help improve future care.
Hoofddorp, North HollandAges 21–90 - NCT06166628Recruiting
Comparing two procedures for knee osteoarthritis pain
This study compares two minimally invasive procedures—embolization (blocking blood flow) and nerve ablation (blocking pain signals)—to see which works better for knee osteoarthritis pain. If you have long-lasting knee pain and are considering knee replacement surgery, this trial may help find another option.
Kingston, OntarioAges 40 years+ - NCT07869680Recruiting
Comparing knee function in people with similar knee arthritis pain
This study looks at how knee osteoarthritis (a common condition where the cushioning in the knee joint wears down) affects physical function, even when people report similar levels of pain. It aims to understand why some people with the same pain might have more difficulty with daily activities, which could lead to better targeted treatments.
MardinAges 40–75 - NCT06221709Recruiting
Radiofrequency for hip arthritis pain: a clinical trial
This trial tests whether a treatment called continuous radiofrequency can reduce pain from hip arthritis. It is for people with moderate arthritis in one hip who have had pain for more than six months.
Brasília, Federal DistrictAges 18 years+ - NCT04688593Recruiting
Follow-up study of a hip implant cup and stem system
This study looks at how well a specific hip implant (the acetabular cup and femoral stem) works over short, mid, and long-term follow-up. It may help you and other patients by improving understanding of implant outcomes after surgery.
KielAges 18 years+ - NCT06237153RecruitingPhase 2
Steroid injection for thumb arthritis pain
This study tests a long-acting steroid injection for thumb arthritis at the base of the thumb. It aims to reduce pain and improve function in people with mild to moderate joint damage.
Stony Brook, New YorkAges 18 years+ - NCT05887284Recruiting
Low-dose radiation study for osteoarthritis pain relief
This study tests whether giving a small amount of radiation to an osteoarthritis joint can improve symptoms. It’s designed for people who are newly starting this kind of treatment and can return for follow-up visits.
Erlangen, BavariaAges 39 years+ - NCT07855367Recruiting
Knee pain relief study for osteoarthritis patients
This study compares two procedures that use extreme cold or heat to target the nerves around the knee, with the goal of reducing pain from knee osteoarthritis. It is specifically for people with advanced knee osteoarthritis who also have bladder cancer.
CairoAges 40 years+ - NCT03491761RecruitingPhase 2
PRP injection versus hyaluronic acid shots for knee arthritis
This trial tests whether a platelet-rich plasma (PRP) shot works better than a standard hyaluronic acid (“gel”) injection to reduce knee osteoarthritis pain. It may help people with ongoing knee pain choose the treatment that relieves symptoms more effectively.
Skokie, IllinoisAges 18–75 - NCT05923736Recruiting
Study of cardiovascular risk in people with digital osteoarthritis
This study looks at how heart-and-blood-vessel risk differs in people with digital osteoarthritis (arthritis affecting the fingers). It may help doctors understand whether finger osteoarthritis is linked with higher cardiovascular risk.
Clermont-FerrandAges 18 years+ - NCT05559463Recruiting
Anti-inflammatory diet for knee arthritis pain relief
This trial studies whether an anti-inflammatory eating plan (the “ITIS diet”) can improve symptoms in people with knee osteoarthritis. It is meant to see if changing what you eat can help reduce pain and improve function.
La Jolla, CaliforniaAges 18 years+ - NCT07853170Recruiting
Comparing 3 vs 5-needle knee nerve blocks for arthritis pain
This study compares two ways of numbing the nerves around the knee to see which gives better pain relief and improves quality of life for people with knee osteoarthritis. It might help you decide if a nerve block is a good option for your knee pain.
Tanta, El-GharbiaAges 18 years+ - NCT07843784Enrolling by invitation
Chatbot pain management for knee osteoarthritis
This trial tests a chatbot program to help people manage knee osteoarthritis pain. You’d use your smartphone to get support and exercises at home, which might help reduce pain and improve daily life.
Hong Kong, Hong KongAges 18 years+ - NCT05933434RecruitingPhase 1/Phase 2
Stem cell injection trial for chronic knee osteoarthritis
This early-phase study tests an injection of donor stem cells placed into the knee joint to help reduce symptoms of knee osteoarthritis. You may be eligible if you have long-lasting knee pain from mild-to-moderate arthritis and meet safety and imaging requirements.
Aarhus NAges 40–75 - NCT06463847RecruitingPhase 1
Stem cell therapy for knee osteoarthritis
This trial tests a new stem cell treatment (UC-MSCs) for knee osteoarthritis. It aims to see if this treatment is safe and can help reduce pain and improve knee function.
Wuhan, HubeiAges 50–70 - NCT07813078Recruiting
Walking on an anti-gravity treadmill for knee osteoarthritis
This study tests whether walking on a special treadmill that reduces the weight on your knees can help with knee pain and function. If you have knee osteoarthritis, this type of training might be an effective way to exercise without causing more joint stress.
Sanok, Podkarpackie VoivodeshipAges 40–70 - NCT07807943Recruiting
Knee arthritis pain relief procedure for cancer patients
This study tests a procedure called geniculate artery embolization (GAE) to reduce knee pain from osteoarthritis in people who also have cancer. It may help those who cannot or do not want to have knee surgery.
Houston, TexasAges 40 years+ - NCT06196567Recruiting
Pulsed magnetic therapy for knee strength before replacement
This study tests whether pulsed electromagnetic field therapy (a non-invasive treatment using magnetic pulses) can improve muscle strength and function in people with severe knee osteoarthritis who are waiting for knee replacement surgery. It may help you feel stronger and move better before your operation.
Hong Kong, NEW TerritoriesAges 50–100 - NCT07796607Enrolling by invitation
Knee cartilage therapy research
This study looks at knee osteoarthritis to find new ways to treat it. If you have knee pain from worn-down cartilage, this research may lead to better therapies.
Kunming, YunnanAges Any age
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Common questions
- Are there clinical trials for osteoarthritis?
- Yes. Clin2 currently lists 592 recruiting osteoarthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.