Clinical trials
Osteoarthritis clinical trials
Below are recruiting osteoarthritis clinical trials, each written for real people, not researchers. We’re tracking 610 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06794632Recruiting
Hand osteoarthritis self-management program
This trial tests a group program to help people with hand osteoarthritis manage daily activities better. It focuses on peer learning and support to improve your ability to do everyday tasks.
Copenhagen, Capital RegionAges 18 years+ - NCT05980793Recruiting
Nerve Treatment for Finger Joint Osteoarthritis
This study tests if a procedure that quiets the nerves around a painful finger joint (PIP joint denervation) can reduce pain and improve hand function for people with osteoarthritis. It offers a possible alternative before considering more invasive surgery.
StockholmAges 18 years+ - NCT07551245Recruiting
High-intensity laser vs traditional treatment for knee osteoarthritis
This study tests whether high-intensity laser therapy works better than traditional physical therapy methods for knee osteoarthritis pain and function. You'll be randomly assigned to receive either laser treatments or standard rehabilitation exercises.
Erbil, Erbil GovernorateAges 30–60 - NCT07542808RecruitingPhase 2/Phase 3
Stem cell treatment vs. hyaluronic acid for knee arthritis
This study tests whether an injection of stem cells (special cells that can help repair tissue) works better than a standard hyaluronic acid injection for knee osteoarthritis pain. Both treatments are injected into the knee to reduce pain and improve function.
Abu DhabiAges 18 years+ - NCT05675527RecruitingPhase 4
Platelet gel (PRP) for shoulder arthritis pain
This trial tests whether platelet-rich plasma (PRP), a blood-based treatment, can reduce pain from shoulder (glenohumeral) osteoarthritis. It also looks at whether PRP works for people who had temporary relief from a numbing/shock injection into the joint.
New York, New YorkAges 18–100 - NCT07405983Recruiting
New study of a thumb joint replacement for arthritis
This study tests a new implant (TOUCH® CMC) for people with thumb arthritis. It aims to see if the implant relieves pain and improves function.
Aurora, ColoradoAges 22 years+ - NCT07371572RecruitingPhase 3
Steroid Injection for Hand Osteoarthritis
This study tests whether a steroid injection into the muscle can reduce pain and improve hand function in people with hand osteoarthritis. It is for those whose pain is moderate to severe and hasn't been helped enough by standard pain medications.
Ubbergen, GelderlandAges 16 years+ - NCT06367283RecruitingPhase 3
Metformin for treating hand osteoarthritis pain
This study tests whether metformin, a common diabetes medication, can reduce pain in hand osteoarthritis. You may be eligible if your hand pain is moderate to severe and you haven't taken metformin before.
Copenhagen, FrederiksbergAges 18 years+ - NCT07313020Enrolling by invitationEarly Phase 1
Handheld imaging to track stem cells in knee osteoarthritis
This trial tests a new handheld imaging device (MPI) to track stem cells injected into the knee. It aims to see if the device can safely monitor how the stem cells move and work in people with knee osteoarthritis.
Haikou, HainanAges 18–75 - NCT07347054Recruiting
Trigger point injection for shoulder arthritis pain
This study tests whether injecting a medication into painful knots in the shoulder muscle can reduce pain from shoulder arthritis. It may be a good option if you have had shoulder pain for at least 3 months and other treatments haven't worked well enough.
Beijing, Beijing MunicipalityAges 45 years+ - NCT07226388Enrolling by invitation
Pyrocarbon hemiarthroplasty vs total shoulder replacement for osteoarthritis
This study compares two types of shoulder replacement surgery for people with osteoarthritis: one that replaces only the ball of the joint (hemiarthroplasty with a pyrocarbon ball) and one that replaces both the ball and socket (total shoulder arthroplasty). The goal is to see which option works better for people with this condition.
St Louis, MissouriAges 40–65 - NCT07226258RecruitingPhase 3
Testing SL1002 for knee pain caused by osteoarthritis
This trial tests a study drug called SL1002 to see if it reduces knee pain from osteoarthritis. It may be an option for people with chronic knee pain who haven't found enough relief from current treatments.
Roseville, CaliforniaAges 40 years+ - NCT07169474Recruiting
Thumb base joint replacement for arthritis
This trial tests a surgery that replaces the joint at the base of the thumb to treat arthritis pain. It may help if you have thumb arthritis that hasn't improved with nonsurgical treatments.
MontpellierAges 18 years+ - NCT06038331RecruitingPhase 2
Umbilical cord membrane for thumb arthritis pain
This trial tests a special umbilical cord membrane placed in the joint to treat arthritis of the thumb base (STT joint). It may be an option if you have pain and disability that haven't improved with other treatments.
BesançonAges 18–75 - NCT07744542Enrolling by invitation
Physical therapy for shoulder arthritis pain
This study tests if a specific physical therapy program can help people with shoulder arthritis (wear-and-tear in the shoulder joint) feel better and move more easily without surgery. It may help you if you have this type of arthritis and have not tried physical therapy recently.
Buffalo, New YorkAges 18 years+ - NCT06163573RecruitingPhase 2
Cartilage repair for kneecap arthritis
This trial tests a lab-grown cartilage implant for people with arthritis behind the kneecap. It aims to reduce pain and improve knee function.
ZagrebAges 18–65 - NCT07468734Recruiting
Shock wave vs. physical therapy for knee arthritis
This study compares two treatments for chronic knee osteoarthritis: shock wave therapy and traditional physical therapy. The goal is to see which one helps reduce pain and improve function better.
CairoAges 40 years+ - NCT06151834Recruiting
Finger joint fusion study using KeriFuse implant
This trial tests a small metal implant (KeriFuse) that fuses the arthritic joint at the tip of your finger to reduce pain. It's for people with finger arthritis who are healthy enough for surgery.
NiceAges 18 years+ - NCT06576583RecruitingPhase 2
Cartilage graft for kneecap arthritis
This trial tests a new graft made from lab-grown cartilage to treat knee pain under the kneecap. It compares the graft to standard surgery for people with moderate-to-severe kneecap arthritis who haven't improved with other treatments.
ViennaAges 18–70 - NCT07544576Enrolling by invitationPhase 4
Knee Arthritis Injection: Two Injection Methods Compared
This study compares two ways of injecting a steroid medication into arthritic knees: using landmark guidance (traditional method) with a higher dose versus ultrasound guidance (imaging) with a lower dose. The goal is to see which approach works better to reduce knee pain and improve function.
Ventura, CaliforniaAges 50 years+ - NCT06082531Recruiting
Platelet-rich plasma injection for knee osteoarthritis
This study tests whether injecting platelet-rich plasma (PRP) from your own blood can help knee pain caused by osteoarthritis or injuries to the cartilage and meniscus. It may be an option if you are between 20 and 60 years old and have not had recent steroid shots or certain health problems.
Xi'an, ShannxiAges 20–60 - NCT07484594Recruiting
Trunk stabilization plus knee rehab for knee-spine syndrome
This trial tests whether adding trunk stabilization exercises to standard knee osteoarthritis rehab can improve outcomes for people with both knee pain and low back pain. It may help if you have moderate knee arthritis and have had back pain for at least 3 months.
Islamabad, ALAges 40–60 - NCT07484529Recruiting
Water vs land exercises for knee osteoarthritis
This study compares two types of physical therapy exercises — one done in water and one done on land — to see which is better for reducing pain and improving movement in people with knee osteoarthritis.
RawalpindiAges 40–65 - NCT07712419Recruiting
Predicting response to knee nerve block with ultrasound
This study is testing if a type of ultrasound can help predict how well a nerve block injection will work for people with severe knee osteoarthritis. It may help doctors choose the best treatment for your pain.
IstanbulAges 45 years+
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Common questions
- Are there clinical trials for osteoarthritis?
- Yes. Clin2 currently lists 610 recruiting osteoarthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.