Clinical trials
Osteoporosis clinical trials
Below are recruiting osteoporosis clinical trials, each written for real people, not researchers. We’re tracking 130 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04704947RecruitingPhase 3
Beta blockers and fracture risk in osteoporosis
This study tests whether using beta blocker blood pressure medicines affects the risk of fractures in people with osteoporosis. It may help doctors understand which medication choices lower fracture risk.
TantaAges 50 years+ - NCT01747291Recruiting
Study of incomplete atypical bone fractures
This study follows people who have had a specific type of bone injury called an atypical fracture, or a similar fracture after little or no trauma. It aims to better understand who is affected and how these injuries behave over time.
Hamilton, OntarioAges 20–100 - NCT06371755Recruiting
Comparing two bone density tests: ultrasound vs X-ray
This study compares two ways to measure bone density: a standard X-ray method (DXA) and a newer ultrasound method (REMS). If you are a woman scheduled for a DXA scan, you may help researchers see if the ultrasound test is just as accurate and easier to use.
Milan, MIAges 30–80 - NCT07579936RecruitingPhase 2
SAL056 bone-strengthening treatment for postmenopausal osteoporosis
This study tests a new injectable medication called SAL056 to strengthen bones and prevent fractures in postmenopausal women with osteoporosis. Researchers want to find the best dose and how often to give it.
Beijing, Beijing MunicipalityAges 45–80 - NCT06643780RecruitingPhase 4
Denosumab for muscle loss in older adults with osteoporosis
This study tests whether a drug called Denosumab, which is used to treat bone loss, can also help improve muscle strength and mass in older adults who have both osteoporosis and sarcopenia. If you qualify, you would receive the drug and be monitored over time to see if it helps your bones and muscles.
Hong KongAges 65 years+ - NCT07162168Recruiting
Using AI to measure bone age from abdominal CT scans
This study uses artificial intelligence to estimate bone age from standard abdominal CT scans. It may help researchers understand how bone age relates to health conditions without extra X-rays.
BeijingAges 18 years+ - NCT06448325Recruiting
Hip replacement fracture risk prediction
This study looks at past hip replacement patients to develop a score that predicts who might have another fracture later. It may help doctors prevent future breaks.
Milan, ItaliaAges 60 years+ - NCT07062978RecruitingPhase 3
Comparing QL1206 to Prolia for postmenopausal osteoporosis
This trial tests a new medication, QL1206, against an approved drug, Prolia, to see if it works as well for treating osteoporosis in postmenopausal women. You may be eligible if you have low bone density and at least one risk factor for fractures.
GuizhouAges 50–85 - NCT07256769Recruiting
Vitamin K, D-chiro inositol and α-lactalbumin for bone health
This trial tests a combination of vitamin K, D-chiro inositol, and α-lactalbumin to help maintain bone strength in women with breast cancer who are on hormone therapy and have low vitamin D. It aims to see if these supplements improve bone health while you take a standard bone medication (alendronate).
Latina, ItalyAges 35–70 - NCT06164795Recruiting
Next steps after strong bone-building therapy
This study looks at what medicine works best for women who have finished a 1-year course of a strong bone-building drug (romosozumab or teriparatide) for severe osteoporosis. The goal is to find a good follow-up treatment to keep bones strong and prevent fractures.
AthensAges 50–85 - NCT07325578Recruiting
Testing a new device for CT-guided spine and pelvis procedures
This study is testing a new device called EPIONE that helps doctors perform CT-guided needle procedures in the spine or pelvis. It aims to see if the device improves accuracy and safety for patients under general anesthesia.
San Diego, CaliforniaAges 22 years+ - NCT03461237Recruiting
Study of care after osteoporotic hip fractures
This study looks at people with osteoporotic hip fractures (breaks in the femur near the hip) and evaluates their care and outcomes. It may help improve how hip fractures are treated in people whose bones are weaker due to osteoporosis.
Beijing, Beijing MunicipalityAges 50–95 - NCT03699228Recruiting
Low-dose chest CT study for adults in China
This study is looking at people ages 30 to 90 who are willing to get a low-dose chest CT scan. It may help researchers improve how health data is collected and understood from scans.
Wuhu, AnhuiAges 30–90 - NCT03921060RecruitingPhase 4
Check osteoporosis markers in people with cystic fibrosis
This study looks for signs (markers) of bone thinning—called osteoporosis—in people with cystic fibrosis. Your participation may help researchers understand how osteoporosis develops in CF and whether a bone-strengthening medicine like denosumab could help, since some participants may need that medication.
Dallas, TexasAges 18–64 - NCT04608630RecruitingPhase 2
Preventing bone loss in ICU patients with anti-bone drugs
This Phase 2 study tests whether zoledronic acid or denosumab can prevent bone thinning in critically ill adults after staying in the ICU. It may help reduce the risk of future bone fractures if your body is at higher risk during and after critical illness.
Sydney, New South WalesAges 50 years+ - NCT04741906Recruiting
Dental implants in people taking antiresorptive medications
This study looks at how well dental implant treatment works in people with cancer or osteoporosis who take antiresorptive medicines. It may help your team understand what to expect for healing and outcomes in your situation.
Copenhagen, DanmarkAges Any age - NCT04787679Recruiting
CT-planned testing to improve hip fracture and replacement care
This study uses your routine pre-surgery CT scan to study a broken or replacement hip bone with computer modeling and lab-style analysis. It aims to help doctors better understand bone healing and improve how hip fractures and replacements are handled.
Miano, MilanoAges 18 years+ - NCT04796350Recruiting
Medicine after hip surgery to help prevent a second hip fracture
This trial tests AGN1 LOEP (a medicine/device placed at the hip surgery site) to help prevent another hip fracture after you’ve had a low-energy hip fracture. You must be eligible for hip repair surgery and be at higher risk for another fracture, with no key exclusions like active cancer or serious kidney disease.
InnsbruckAges 65–91 - NCT05246813Recruiting
Study blood cell changes in older adults
This study looks at how blood-forming stem cells change in people with clonal hematopoiesis (CHIP), a common age-related blood condition. It may help researchers understand what these changes mean and who might be at higher risk for future blood problems.
Bonheiden, BelgiëAges 55 years+ - NCT05266976Recruiting
Exercise types and bone markers in healthy older veterans
This study compares different ways of exercising to see how they affect “bone-related” blood markers in older adults. It may help you and researchers understand which exercise patterns support healthy bones.
Aurora, ColoradoAges 60 years+ - NCT05732870Recruiting
Study looks for blood and gene signals that affect bone health
This study collects information and samples around the time of certain bone or joint surgeries (like joint replacement or fracture repair) to learn what factors help or harm bone healing. The results may help find better targets to improve long-term bone health and recovery.
London, Greater LondonAges 18–110 - NCT05845021Recruiting
Screening and referral for bone health after hip or knee surgery
This study looks at a simple plan for surgeons to identify people with low bone strength (osteoporosis) and refer them for bone health care after hip or knee replacement surgery. It may help you get evaluated and treated earlier if you have osteoporosis.
Columbia, MarylandAges 50 years+ - NCT05906147Recruiting
Bone health improvement program for adults over 40
This study tests a structured bone health improvement program for adults over age 40 who are attending a health checkup at the hospital. It aims to improve or maintain bone strength, using bone density measurements as part of the study.
Changsha, HunanAges 40–100 - NCT05923736Recruiting
Study of cardiovascular risk in people with digital osteoarthritis
This study looks at how heart-and-blood-vessel risk differs in people with digital osteoarthritis (arthritis affecting the fingers). It may help doctors understand whether finger osteoarthritis is linked with higher cardiovascular risk.
Clermont-FerrandAges 18 years+
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Common questions
- Are there clinical trials for osteoporosis?
- Yes. Clin2 currently lists 130 recruiting osteoporosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoporosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoporosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.