Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,472 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06491537Recruiting
Time-restricted eating for losing weight after having a baby
This study tests whether eating only during a specific daily window (time-restricted eating) helps new moms lose weight. It may be an option if you are 6 to 16 weeks postpartum and have a body mass index (BMI) of 25 or higher.
Birmingham, AlabamaAges 18 years+ - NCT06432790Recruiting
In-person vs online healthy living and asthma program for kids
This study compares two programs for helping children with asthma who are overweight or obese — one that is held in person and another that is offered online. It tests whether learning about healthy habits and asthma management works better when done face-to-face or on a computer.
Boston, MassachusettsAges 4–17 - NCT06426693Recruiting
Brain training for food cravings
This study tests a brain-training technique called neurofeedback to help reduce food cravings. You'll get MRI scans while learning to control brain activity related to cravings.
New Haven, ConnecticutAges 18–60 - NCT06382298Recruiting
Cottonseed oil vs. similar oil for heart health
This study compares the effects of cottonseed oil versus a similar oil on heart health. It is for people with high cholesterol or who are overweight and want to see if changing cooking oils can improve their cholesterol levels.
Athens, GeorgiaAges 25–75 - NCT06390345Recruiting
Telehealth lifestyle and exercise for COPD and sleep apnea
This study tests a telehealth program that combines lifestyle coaching and exercise to help people with both COPD and sleep apnea improve their breathing and daily function. It may be a good fit if you are overweight, have a history of smoking, and feel short of breath during light activity.
Boise, IdahoAges 18 years+ - NCT06370845RecruitingEarly Phase 1
Smell test to find natural odor in spinal fluid
This study investigates whether a natural smell can be detected in the fluid around your brain and spine (cerebrospinal fluid) after you sniff it. It aims to understand how smells enter the brain in people with different body weights who are already scheduled for a routine spinal tap.
BaselAges 18–60 - NCT06354088RecruitingPhase 1
Study of alpelisib for insulin resistance
This study tests a single dose of a drug called alpelisib (a PI3K inhibitor) to see how it affects insulin and blood sugar in people who are either insulin sensitive or insulin resistant. The goal is to understand why some people become resistant to insulin, which may help find new treatments for diabetes and related conditions.
New York, New YorkAges 18–70 - NCT06325722Recruiting
Low fat vs. low carb diet order and body fat change
This study compares how the order of low fat versus low carb diets affects body fat changes. It may help you understand which diet sequence works best for weight loss.
Bethesda, MarylandAges 18–50 - NCT06323070Recruiting
Watermelon vs. low-fat cookies for wellness
This trial compares eating watermelon or low-fat cookies to see how they affect your overall wellness. It will help determine if one snack is better for your health.
San Diego, CaliforniaAges 18–50 - NCT06277232Recruiting
Nutrition care for chronic pain patients
This trial tests a nutrition care program for people with chronic pain who are also overweight. You will receive support to improve your diet while attending a pain rehabilitation program.
Linköping, Östergötland CountyAges 18 years+ - NCT06282952Recruiting
Stool transplant for C-section babies' health
This trial tests whether giving a special stool transplant (fecal microbiota) to healthy babies born by C-section can improve their health. It aims to see if this treatment helps replace good bacteria that are normally passed during a vaginal birth.
OuluAges birth–6 hours - NCT06173778RecruitingPhase 2
Semaglutide for weight management after quitting smoking
This study tests whether the drug semaglutide (often used for weight loss) can help people who quit smoking avoid gaining weight. It's for people who are overweight or have weight-related health issues and want to stop smoking.
Austin, TexasAges 18–75 - NCT06147973Recruiting
Healthy lifestyle program for teen girls
This study tests a healthy lifestyle program that helps teen girls accept their bodies and make positive changes. It aims to see if this approach can improve weight-related health and well-being.
Philadelphia, PennsylvaniaAges 14–19 - NCT06105957Recruiting
Digital weight loss program for rural adults
This study tests a digital weight loss program designed for adults living in rural areas. It uses a smartphone app, website, and video group sessions to help you lose weight through diet and physical activity.
Columbia, South CarolinaAges 18 years+ - NCT06069622Recruiting
How a gene affects weight-loss treatment response
This study looks at how a weight-loss medication affects people with obesity who may have a specific gene difference (caveolin-1). It aims to understand why some people respond differently to GLP-1 treatments like semaglutide.
Boston, MassachusettsAges 18 years+ - NCT06044935Recruiting
Nicotinamide riboside for fat burning and metabolism
This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) helps the body burn fat more efficiently during exercise. It may be a good option if you are overweight or have a specific type of diabetes (MODY2) and want to see if a natural supplement can boost your metabolism.
Bethesda, MarylandAges 18–65 - NCT06009276Recruiting
Gut bacteria, muscle blood flow, and fitness study
This study looks at how the bacteria in your gut affect blood flow to your muscles and your overall fitness. You will provide samples and do some exercise tests to help researchers understand this link.
Charlottesville, VirginiaAges 18 years+ - NCT05943626Recruiting
Sleep timing changes to improve heart and blood sugar health
This study tests whether changing your sleep habits can improve heart-related health and blood sugar control. You may be asked to follow a sleep schedule and other routines, and outcomes will be measured over time.
Salt Lake City, UtahAges 18–45 - NCT05872022Enrolling by invitation
Safety study of Wegovy exposure during pregnancy
This study tracks the safety of taking Wegovy during pregnancy. Researchers want to understand potential risks and outcomes when people are exposed to Wegovy in early or any stage of pregnancy.
Princeton, New JerseyAges 15–50 - NCT05826379Enrolling by invitation
Daily goal setting to boost movement and brain health
This trial tests whether a daily goal-setting program and activity tracking can increase everyday physical activity and support thinking/brain health in midlife. You may be asked to wear devices and meet activity-monitoring requirements during the study.
Hershey, PennsylvaniaAges 30–70 - NCT05811624Recruiting
Lifestyle program for weight and chronic low back pain
This trial studies whether a lifestyle change program (often diet and activity habits) can reduce long-lasting low back pain in overweight or obese adults. It also aims to see if people can keep their usual care while adding the lifestyle program.
BrusselsAges 18–65 - NCT05807594Recruiting
Online program to help manage weight gain during pregnancy
This trial tests an at-home (online) coaching program to help pregnant people gain weight at a healthier rate. It may help you stay on track during pregnancy and understand what changes work best for you.
University Park, PennsylvaniaAges 18–45 - NCT05748158Recruiting
Study of why weight returns after behavioral weight loss
This study looks at what makes some people regain weight after losing weight in a behavioral weight loss program. You may help researchers understand the role of habits, metabolism, and energy use so better prevention strategies can be developed.
New York, New YorkAges 25–59 - NCT05681468Recruiting
Ketogenic diet trial for blood sugar and inflammation outcomes
This study compares two versions of a ketogenic (very low-carb) diet to see how they affect blood sugar control and inflammation. It may help people with overweight or obesity who have pre-diabetes-level blood sugar understand which fat sources work better.
Edmonton, AlbertaAges 18–70
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Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,472 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.