Clinical trials
Pain After Surgery clinical trials
Below are recruiting pain after surgery clinical trials, each written for real people, not researchers. We’re tracking 417 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06821516Recruiting
Comparing two nerve blocks for hip replacement pain
This study compares two different nerve block techniques to manage pain after a total hip replacement. The goal is to find out which method provides better pain relief and recovery.
Istanbul, Türki̇yeAges 18 years+ - NCT06878014RecruitingPhase 4
Morphine for pain relief after hip replacement surgery
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Sosnowiec, Silesian VoivodeshipAges 18–75 - NCT07218133Recruiting
Ear Stimulation to Reduce Pain After Spine Surgery
This trial tests whether a gentle electrical stimulation delivered through the ear can reduce inflammation and pain after major spinal fusion surgery. If you are having a long spinal fusion, you might be able to join.
St Louis, MissouriAges 18 years+ - NCT07879404Enrolling by invitation
Cold water spray for throat pain and thirst after thyroid surgery
This trial tests whether using a cold water spray can help reduce swallowing difficulty, pain, and thirst after thyroid surgery. It may provide a simple, non-medication way to feel more comfortable during recovery.
Ankara, AnkaraAges 18 years+ - NCT07859397Recruiting
Pain relief options for knee ligament surgery
This study compares two nerve-block approaches to see which provides better pain relief after knee ligament reconstruction surgery. If you are having this surgery, joining could help manage your pain more effectively.
AnkaraAges 18–65 - NCT05253326Recruiting
Relaxing muscle exercises after spine surgery
This trial tests whether a structured “progressive muscle relaxation” routine can reduce pain and help recovery after spine surgery. You may be asked to learn and practice the relaxation steps even if you’ve never done them before.
Istanbul, ÜsküdarAges 18 years+ - NCT07632833Recruiting
Comfort tote for teens recovering from spine surgery
This study tests whether giving teens a special comfort tote with calming items helps them feel better and recover more smoothly after surgery for scoliosis. It is for patients aged 10 to 21 who are having spinal fusion at a specific hospital.
New York, New YorkAges 12–21 - NCT07588230Recruiting
Nerve Block for Minimally Invasive Heart Valve Surgery Pain
This study tests a targeted nerve block (pain-numbing injection) to help manage pain after minimally invasive heart valve surgery. Researchers want to see if this technique reduces pain and the need for opioid medications during recovery.
Diyarbakır, Outside of the USAges 18–75 - NCT07575230Enrolling by invitationPhase 4
Pain relief after skin cancer surgery: new drug vs standard
This study compares a new pain medication (suzetrigine) to a common pain reliever (Norco) for people recovering from Mohs micrographic surgery, a specialized procedure to remove skin cancer. The goal is to see if the new medication works better and is safer for post-surgery pain.
Dallas, TexasAges 18–89 - NCT07540689Recruiting
Pain Relief Method for Children's Minimally Invasive Belly Surgery
This study tests a new pain-relief technique called M-TAPA for children ages 1–7 having small-incision belly surgery. Researchers want to see if this method helps reduce pain better than standard approaches after surgery.
Cairo, ElmanialAges 1–7 - NCT07502612Recruiting
Spinal cord stimulation medication tapering study
This study tests whether lowering pain medication can improve how well spinal cord stimulation works. It is for people who already take certain pain medicines and are scheduled to try a spinal cord stimulator.
WilrijkAges 18 years+ - NCT07442721Recruiting
Comparing two types of nerve blocks for hip replacement pain
This study compares two different nerve block methods to see which provides better pain relief for people having a partial hip replacement. It will help doctors choose the best way to manage pain after surgery.
El Fayoum Qesm, Faiyum GovernorateAges 50–90 - NCT07039812Recruiting
Virtual Reality for Pain During Dressing Changes After Heart Surgery
This study tests if using virtual reality or an eye mask during wound dressing changes can help reduce pain and anxiety after coronary artery bypass surgery. It aims to find a drug-free way to make dressing changes more comfortable.
Istanbul, MarmaraAges 18–65 - NCT05141591Recruiting
Anxiety before ENT surgery and opioid use after surgery
This trial looks at whether people’s anxiety before ear, nose, and throat (ENT) surgery affects how much pain medicine (opioids) they need after surgery. It may help doctors better plan pain control based on anxiety level and possibly gender-related patterns.
Vienna, State of ViennaAges 18 years+ - NCT06818396Recruiting
Pain relief for hip surgery: comparing two methods
This study compares two ways to manage pain during hip surgery: a nerve block in the groin area versus a spinal medication. The goal is to find which approach offers better pain control with fewer side effects.
CairoAges 21 years+ - NCT06660680Enrolling by invitationPhase 3
Methylene blue for pain after hemorrhoid surgery
This trial tests whether injecting methylene blue (a dye) into the area around the anus during hemorrhoid surgery can reduce pain after the operation. If you are having Milligan-Morgan surgery for mixed hemorrhoids, this study may help find a way to make your recovery more comfortable.
Hefei, AnhuiAges 18–75 - NCT06562634Enrolling by invitation
Ultrasound-guided nerve block for knee surgery pain relief
This study tests a nerve block (erector spinae plane block) to see if it reduces pain after open knee surgery. It aims to find a better way to manage pain with fewer side effects.
CairoAges 18–65 - NCT04040452RecruitingPhase 4
Continuous versus intermittent ketorolac for kids’ heart surgery pain
This study compares two ways of giving ketorolac (a pain medicine) to young children after heart surgery—continuous drip versus doses at set times. It aims to find which approach controls pain better with fewer side effects.
Phoenix, ArizonaAges 3 months–4.9 years - NCT07211308Recruiting
A study of spinal cord stimulation for chronic leg pain
This trial tests a type of spinal cord stimulation (DTM SCS) for people with chronic leg or foot pain caused by nerve damage (PSPS-T2). It aims to see if this treatment can safely reduce pain and improve daily life.
BrusselsAges Any age - NCT06709391Recruiting
Spinal fusion vs. no surgery for chronic low back pain
This trial tests whether a spinal fusion surgery is better than staying with non-surgical treatments for people with long-term, severe low back pain from worn-out discs in the lower spine. It aims to find out which approach offers better pain relief and quality of life.
GothenburgAges 25–65 - NCT06731998Recruiting
Improving pain control after cancer surgery
This study compares different methods of managing pain after minimally invasive surgery for abdominal cancers. It aims to find which approach works best to reduce pain and improve recovery.
Pittsburgh, PennsylvaniaAges 18–89 - NCT07693270Recruiting
Study looking for markers of pain and opioid response after injury or surgery
This study is looking for biological markers (like blood tests) that can predict how people will respond to pain and opioids after a traumatic injury or surgery. The goal is to help doctors tailor pain treatment to each person.
La Jolla, CaliforniaAges 18 years+ - NCT06817239Recruiting
Low-dose esketamine for preventing confusion after surgery in older adults
This study tests whether a low dose of the medicine esketamine can help prevent confusion after surgery in older adults at higher risk. You may qualify if you are 65 or older, planning a major non-cardiac surgery, and have certain health conditions like high blood pressure or diabetes.
Fuzhou, FujianAges 65–90 - NCT07365800Enrolling by invitationPhase 4
Combination pain control after complex spine surgery
This study tests a combination of three medications (methadone, dexmedetomidine, and ketamine) to control pain after major spine surgery. If you are having complex spine surgery, this trial may offer better pain relief without needing as much opioid medication.
Columbia, MissouriAges 18–79
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Common questions
- Are there clinical trials for pain after surgery?
- Yes. Clin2 currently lists 417 recruiting pain after surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain after surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain after surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.