Clinical trials
Pain and Anxiety clinical trials
Below are recruiting pain and anxiety clinical trials, each written for real people, not researchers. We’re tracking 151 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04014829Recruiting
Study of pain processing after planned hysterectomy
This trial looks at how the nervous system and fear of pain may affect pain after a planned hysterectomy. If you qualify, you may be asked about pain levels and pain sensitivity to better understand who may have more pain recovery challenges.
SingaporeAges 21–80 - NCT07194967Enrolling by invitation
Virtual Reality for Pain Relief During Labor
This trial tests whether using virtual reality can help reduce pain and anxiety during labor. If you are having a low-risk pregnancy and plan a vaginal delivery, you may be able to use a VR headset during contractions to distract from pain.
Ben ArousAges 18–45 - NCT07045116Recruiting
Electronic vs. standard syringe for kids' dental pain and anxiety
This study tests if an electronic syringe causes less pain and anxiety in children during a dental numbing shot compared to a conventional syringe. It is for healthy 6-8 year olds getting their first dental visit and who need a filling on a baby molar on each side of the mouth.
CairoAges 6–8 - NCT06795126Enrolling by invitation
Virtual reality for pain and anxiety in kids getting IVs
This study tests if a virtual reality game called Little NIRVANA can help reduce pain and anxiety in children getting an IV. It's for kids ages 2 to 8 in the emergency department.
Columbus, OhioAges 2–8 - NCT07055178Recruiting
Virtual reality for pain and anxiety during vasectomy
This study tests if using a virtual reality headset during a vasectomy can help lower pain and anxiety. It compares VR with standard care to see which works better for patients.
Winnipeg, ManitobaAges 18 years+ - NCT07101172Enrolling by invitation
Stress ball for anxiety and pain during prostate biopsy
This study tests whether using a stress ball during a prostate biopsy can help reduce anxiety and pain. It may be an option if you are having your first biopsy and can squeeze a ball.
Çorum, MerkezAges 18 years+ - NCT07023692Enrolling by invitation
Using visual and sound tricks to ease pain and worry during a bone marrow test
This trial tests whether watching a video or listening to sounds can help reduce pain and anxiety during a bone marrow aspiration or biopsy. It's for adults who are either healthy volunteers or patients without a blood cancer diagnosis, and who need this test at the clinic in Lund, Sweden.
Lund, Skåne CountyAges 18 years+ - NCT07547371Recruiting
Aromatherapy and Digital Anesthesia for Dental Anxiety in Children
This study tests whether aromatherapy (calming scents) and digital anesthesia (numbing technology) can help reduce anxiety and pain when children need a baby molar removed. The goal is to find gentler ways to keep children comfortable during dental procedures.
Istanbul, IstanbulAges 6–12 - NCT07072559Enrolling by invitation
Can a dental game reduce pain and anxiety during kids' pulp treatment?
This study tests whether playing a dental-themed game on a mobile device can help children aged 4 to 7 feel less pain and anxiety during a pulpotomy (a procedure to treat deep cavities in baby teeth). It aims to make the dental visit easier for kids who are cooperative but may be nervous.
Al MansurahAges 4–7 - NCT07098390Recruiting
Relaxation to Reduce Fear and Pain After Joint Replacement
This study tests whether a simple relaxation technique (progressive muscle relaxation) can help reduce fear of falling, pain, and anxiety after hip or knee replacement surgery. It may be a safe, drug-free way to feel better during recovery.
AnkaraAges 18 years+ - NCT06726239Recruiting
Relaxation exercises before getting up after heart bypass
This study tests whether doing gentle relaxation exercises before getting out of bed can help reduce pain, anxiety, and stress after heart bypass surgery. It may make recovery more comfortable.
Istanbul, IstanbulAges 35–65 - NCT07518953Recruiting
Can Music Help With Pain During a Nail Biopsy?
This study tests whether listening to music during a nail biopsy—a small procedure to remove a sample of nail tissue—can reduce pain and anxiety. You would listen to music during the procedure and answer a few questions about how you felt.
New York, New YorkAges 18 years+ - NCT07371442Enrolling by invitation
Audio distraction and acupoint stimulation for kids during tooth extraction
This study tests two non-drug methods to help children feel less pain and worry during a tooth extraction: an audio-video distraction (like a movie or music) and a special pressure point (acupoint) stimulation on the hand. It aims to see which approach works best for kids ages 5 to 8 who need a baby tooth removed.
Al MansurahAges 5–8 - NCT07769385Enrolling by invitation
Robotic fish and aquarium to ease pain and fear in children
This trial tests whether using a robotic fish or watching an aquarium can help reduce pain, fear, and anxiety in children during medical procedures. It might make the experience more comfortable for your child.
Bingoel, TurkeyAges 5–10 - NCT07310004Recruiting
VR vs Music for Breast Biopsy Anxiety
This trial compares using a virtual reality headset versus listening to relaxing music to help lower your anxiety and pain during a breast biopsy. Both methods are non-drug ways to help you feel more comfortable during the procedure.
Los Angeles, CaliforniaAges 18 years+ - NCT03415620Recruiting
Music listening during surgery to reduce anxiety and pain
This study tests whether listening to music around the time of surgery can lower anxiety and pain, reduce how much pain medicine you need, and improve satisfaction. You may be asked to fill out brief questionnaires before and after your procedure.
SingaporeAges 21–70 - NCT06616324Recruiting
Virtual reality to reduce pain during kidney stone treatment
This study tests whether using a virtual reality (VR) headset during a kidney stone treatment called ESWL can help reduce pain and anxiety. If you're scheduled for ESWL at a hospital in Region Zealand, you may be able to use VR to distract yourself during the procedure.
RoskildeAges 18 years+ - NCT07771205Recruiting
Aromatherapy for surgical anxiety and pain
This study tests whether breathing in relaxing scents before surgery can reduce anxiety and pain. If effective, it could offer a simple, drug-free way to help you feel calmer during your procedure.
Stockton, CaliforniaAges 18 years+ - NCT06986122Recruiting
Testing virtual reality to help with pain
This study tests whether virtual reality can help change how you feel pain. You'll be asked to complete tasks and rate your experience.
Hanover, New HampshireAges 18–55 - NCT04912531Recruiting
Virtual reality and smell tools to ease surgery pain
This trial tests whether a combination of virtual reality and guided smells can reduce pain and anxiety around major heart and chest surgeries. If you’re scheduled for one of the listed operations, the study may help make recovery feel more comfortable by using sensory-based distraction.
Boston, MassachusettsAges 18 years+ - NCT07085065Recruiting
Virtual reality for pain and anxiety during blood cancer procedures
This trial tests whether watching a virtual reality experience during a medical procedure can help reduce pain and anxiety for people with blood cancers. You may be able to take part if you are getting a bone marrow biopsy, spinal tap, blood draw, or chemotherapy.
Tunis, Sfax GovernorateAges 6 years+ - NCT07374354Recruiting
Pain and anxiety control for kids with MIH
This study tests a pain-relieving medicine given before dental treatment to see if it helps reduce pain and anxiety in children with molar incisor hypomineralization (MIH), a condition that causes weak enamel on molars and front teeth.
GizaAges 6–12 - NCT06783946Enrolling by invitation
Meditation for pain and anxiety after kidney stone surgery
This study is testing whether guided meditation can help reduce pain, discomfort, and anxiety after a kidney stone removal procedure called ureteroscopy. If you or your child is a teenager or adult scheduled for this surgery, meditation might be a calming tool to try before and after the procedure.
Philadelphia, PennsylvaniaAges 12 years+ - NCT07750236Recruiting
Stress ball for easing fear and pain during allergy testing
This trial gives children a stress ball to hold during their allergy skin test, to see if it helps reduce fear, anxiety, and pain, and makes the experience more satisfying for the family.
TarsusAges 4–10
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Common questions
- Are there clinical trials for pain and anxiety?
- Yes. Clin2 currently lists 151 recruiting pain and anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain and anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain and anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.