Clinical trials
Pain Management After Surgery clinical trials
Below are recruiting pain management after surgery clinical trials, each written for real people, not researchers. We’re tracking 180 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07423650RecruitingPhase 4
Continuous Nefopam infusion after pancreas surgery
This trial tests if giving a steady dose of a painkiller called nefopam through an IV can help manage pain after a Whipple procedure (pancreatoduodenectomy). It aims to see if this approach reduces the need for other pain medications and improves recovery.
Cluj-Napoca, ClujAges 18–80 - NCT07445854Recruiting
Sensory mapping after nerve blocks for gallbladder surgery
This trial measures how different regional anesthesia techniques affect sensation on the skin. It may help doctors understand how to better manage pain after gallbladder surgery.
Samsun, IlkadımAges 18–75 - NCT07524673Recruiting
Comparing two nerve blocks for chest surgery pain
This study tests two different numbing techniques (nerve blocks) to see which one works better for pain relief after minimally invasive chest surgery. Both methods inject medicine near nerves to reduce post-surgery pain.
Sivas, MerkezAges 18 years+ - NCT07215546Enrolling by invitation
Stopping pain after heart surgery with a special chest closure
This trial tests a new device to close the breastbone after open-heart surgery to see if it helps reduce the need for prescription pain medicine. The device is designed to hold the bone together more securely, which may lead to less pain and faster recovery.
Naples, FloridaAges 19–80 - NCT05964868Enrolling by invitationPhase 3
Liposome anesthesia to reduce pain after nose surgery
This Phase 3 study tests whether a special form of local numbing medicine (liposomal bupivacaine) helps reduce pain after septorhinoplasty (nose and septum surgery). You may be considered if you’re planning this surgery and can follow study instructions before and after.
Hershey, PennsylvaniaAges 18–99 - NCT03365908Enrolling by invitation
Pain Management After ACL Reconstruction Surgery
This study looks at ways to manage pain in adults who are getting surgery to repair a torn ACL (a knee ligament). It may help improve comfort and recovery after ACL reconstruction.
Sacramento, CaliforniaAges 18–45 - NCT06100822RecruitingPhase 1
Testing metformin for chronic Achilles tendon pain
This study tests whether a common diabetes medication, metformin, can help people with chronic Achilles tendon pain. If you have this condition and meet certain health requirements, you may be able to join.
Pittsburgh, PennsylvaniaAges 18–50 - NCT06969456Recruiting
Exercise and nerve stimulation for chronic back pain
This study looks at whether combining exercise with a type of nerve stimulation (called neuromodulation) can help people with long-term spinal pain that has nerve involvement. It may be an option if you have had pain for at least 6 months and it is severe.
Valencia, ValenciaAges 18–70 - NCT06707363Recruiting
Psychological factors and pain after orthopedic surgery
This study looks at how your thoughts and feelings affect your pain after orthopedic surgery. Researchers want to understand these factors to improve care for future patients.
Krakow, MalopolskaAges 18–65 - NCT06809543Recruiting
Testing Tropho Tend for painful rotator cuff tendinopathy
This study tests a product called Tropho Tend to see if it safely reduces pain and improves function in people with rotator cuff tendinopathy, a condition where the shoulder tendons are sore and irritated. If you have had shoulder pain for at least 6 weeks and it is at least a 4 on a 10-point scale, this trial might be a good fit.
Sassuolo, ItalyAges 18 years+ - NCT07328256Recruiting
Comparing two muscle relaxation techniques for neck pain relief
This study looks at two different gentle stretching methods to see which works better for relieving neck pain. It might help if you have had neck pain for a while and it limits your movement.
Islamabad, Punjab ProvinceAges 19–44 - NCT06754657RecruitingPhase 4
Comparing pain blocks for rotator cuff surgery recovery
This trial tests two ways of numbing the shoulder during rotator cuff surgery to see which leads to better recovery after outpatient surgery. It compares a single injection with a continuous pump that delivers numbing medicine for a longer time.
SantiagoAges 18–75 - NCT07500012Recruiting
Ear nerve stimulation for breast cancer pain
This study tests whether gentle electrical stimulation of a nerve in your ear (called taVNS) can help reduce pain and improve symptoms for breast cancer survivors. You would need to have finished your main treatments, have ongoing pain, and be willing to provide stool samples and undergo brain scans.
Tallahassee, FloridaAges 18–79 - NCT06728579RecruitingPhase 2
Group therapy for joint pain in breast cancer survivors
This study tests two supportive group programs—one using mindfulness skills, the other providing supportive talk therapy—to help breast cancer survivors manage joint pain caused by hormone-blocking pills. If you have ongoing joint pain and are taking an aromatase inhibitor, you may be able to join a free, video-based group.
San Diego, CaliforniaAges 18 years+ - NCT02390973Recruiting
Bariatric-style surgery vs best diabetes care for long remission
This trial compares surgery plus follow-up care versus the best non-surgical (medical) treatment to help people keep type 2 diabetes in remission for a long time. It may be an option if you have higher body weight and diabetes that’s not well controlled, but safety checks are strict.
Québec, QuebecAges 18–60 - NCT06381791RecruitingPhase 1/Phase 2
CBD for pain after shoulder surgery
This study tests if CBD (a cannabis extract) can help manage pain after rotator cuff repair surgery. It aims to find a better way to control pain and reduce the need for stronger painkillers.
Houston, TexasAges 18 years+ - NCT06308029Recruiting
E-health pain self-management for breast cancer survivors
This trial tests an online program to help people manage lasting pain after breast cancer treatment. It's designed for those whose pain still gets in the way of daily life, even after finishing primary treatment.
AntwerpAges 18 years+ - NCT07717151Recruiting
Preventing long-term pain after surgery for chronic opioid users
This trial tests a method to prevent chronic pain after surgery in people who already take opioids regularly. It may help reduce long-term pain and improve recovery.
AmiensAges 18 years+ - NCT07310953Recruiting
Using new pain scales to guide rescue pain medicine after surgery
This trial tests if a simple pain scale (the NVS and PFAS) can help doctors better decide when to give extra pain medicine after surgery. It may help control pain more quickly and effectively after a procedure called VATS.
VigoAges 18 years+ - NCT07309731Recruiting
Hot vs. cold radiofrequency for chronic low back pain from facet joints
This trial compares two types of radiofrequency treatment (cooled vs. thermal) to see which works better for chronic pain coming from the small joints in your lower back. It is for people who have had back pain for at least 3 months and haven't gotten enough relief from usual treatments like pain medicine or physical therapy.
Zagazig, ElsharqyaAges 30–70 - NCT06660680Enrolling by invitationPhase 3
Methylene blue for pain after hemorrhoid surgery
This trial tests whether injecting methylene blue (a dye) into the area around the anus during hemorrhoid surgery can reduce pain after the operation. If you are having Milligan-Morgan surgery for mixed hemorrhoids, this study may help find a way to make your recovery more comfortable.
Hefei, AnhuiAges 18–75 - NCT07295457Recruiting
Exercise to prevent pain from hormone therapy in breast cancer
This trial tests whether starting a gentle exercise program early can help prevent or reduce joint and muscle pain caused by aromatase inhibitors (a common breast cancer medicine). It is for women with hormone-sensitive breast cancer who are not yet experiencing severe pain from their treatment.
LyonAges 18–75 - NCT07313566Recruiting
Rehab pathway vs usual care after lumbar spine surgery
This trial compares a new rehab program called R3 (which includes pre-surgery preparation and post-surgery recovery support) with standard care for people having lumbar spine surgery. It aims to see if the R3 pathway helps you recover better and return to work faster.
AntwerpAges 18–65 - NCT06065150Recruiting
Early surgery vs 3-day waiting for bowel blockage
This trial compares two approaches for a sudden blockage in the small intestine caused by scar tissue: having surgery right away versus waiting up to three days with non-surgical care. It aims to see which approach leads to better outcomes, so you and your doctor can make a more informed choice.
AmiensAges 18 years+
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Common questions
- Are there clinical trials for pain management after surgery?
- Yes. Clin2 currently lists 180 recruiting pain management after surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain management after surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain management after surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.