Clinical trials
Pain Management clinical trials
Below are recruiting pain management clinical trials, each written for real people, not researchers. We’re tracking 338 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06995534Recruiting
Splint or Exercise for De Quervain's Wrist Pain
This trial compares wearing a splint versus doing specific exercises to treat De Quervain's tenosynovitis, a condition that causes wrist pain and swelling. It may help if you have new or worsening wrist pain without other injuries or diseases.
KonyaAges 18–65 - NCT06977321Recruiting
Taping vs mud therapy for carpal tunnel syndrome
This study tests whether taping therapy (kinesiotaping) or a mud pack treatment (peloidotherapy) can help reduce pain and improve function for people with mild to moderate carpal tunnel syndrome. It may be an option if you want non-surgical, drug-free relief.
KonyaAges 1.5 years–5.4 years - NCT06964282Recruiting
Comparing Two Nerve Blocks for Hip Replacement Pain Relief
This study compares two types of nerve blocks (iliopsoas block and PENG block) to see which one provides better pain relief and recovery after hip replacement surgery. If you are having a hip replacement with spinal anesthesia, you may be a good candidate.
LiègeAges 18 years+ - NCT06953752Recruiting
Music during atrial fibrillation ablation under light sedation
This study tests whether listening to music during a common heart procedure for atrial fibrillation (called catheter ablation) can improve your experience while you are awake but relaxed. It may help you feel calmer and more comfortable.
Shaoxing, ZhejiangAges 18–80 - NCT06931743Recruiting
Electrical stimulation for pain after thyroid surgery
This trial tests if electrical stimulation can help reduce pain after thyroid surgery. It is for people who have at least moderate pain after their operation.
Shanghai, Changning DistrictAges 18 years+ - NCT05427058Recruiting
Nerve blocks to treat hard-to-control cancer pelvic pain
This trial tests two types of pain-relieving nerve blocks for people with severe cancer pain in the pelvis or perineum that has not improved enough with standard stepwise pain medicines. It may help reduce pain and lessen bothersome side effects from pain pills.
Malang, East JavaAges 18 years+ - NCT06745388RecruitingPhase 4
Magnesium for cramping during hysteroscopy or D&C
This study tests whether magnesium can reduce cramping during a hysteroscopy or D&C. If you are having one of these procedures and are not on certain medications, you may qualify.
Royal Oak, MichiganAges 18 years+ - NCT06505187RecruitingPhase 2
Celecoxib for Pain After Parotid Gland Surgery
This trial is testing whether the pain reliever celecoxib (Celebrex) can help control pain after a specific type of salivary gland surgery called superficial parotidectomy. If you're having this surgery, you may be able to join and take celecoxib for pain rather than other common pain medicines.
Madison, WisconsinAges 18 years+ - NCT06429501RecruitingPhase 2
Numbing medicine for facial fracture surgery
This study tests numbing medicine (local anesthetic) given during surgery for broken facial bones, like the jaw or cheekbones. The goal is to see how well it works and if it helps recovery.
St Louis, MissouriAges 18 years+ - NCT06406647Recruiting
Nerve block for arm surgery
This trial tests a nerve block to help with pain during and after upper arm surgery. The goal is to see if it works well and is safe for patients.
AsyutAges 20–65 - NCT06406712Recruiting
Nerve block for arm vascular surgery
This trial tests a nerve block to numb the arm during vascular surgery. It may help manage pain and reduce the need for general anesthesia.
AsyutAges 20–65 - NCT04979338RecruitingPhase 3
Opioid-sparing pain control for gender-affirming surgery
This Phase 3 study tests ways to manage pain during and after gender-affirming surgery while using less opioid medicine. It may help improve comfort after surgery and reduce opioid-related side effects.
Los Angeles, CaliforniaAges 18 years+ - NCT05964868Enrolling by invitationPhase 3
Liposome anesthesia to reduce pain after nose surgery
This Phase 3 study tests whether a special form of local numbing medicine (liposomal bupivacaine) helps reduce pain after septorhinoplasty (nose and septum surgery). You may be considered if you’re planning this surgery and can follow study instructions before and after.
Hershey, PennsylvaniaAges 18–99 - NCT05705128Enrolling by invitationPhase 2/Phase 3
Dexmedetomidine to help pain after shoulder surgery
This trial studies whether dexmedetomidine can reduce pain after elective shoulder arthroscopy surgery done under general anesthesia. If you’re eligible, it may help improve postoperative comfort and reduce the need for additional pain treatment.
AsyutAges 18–60 - NCT05592132Recruiting
Virtual reality to help children handle cancer treatment pain
This trial studies whether virtual reality can reduce pain and discomfort during painful medical procedures for children getting care for benign (non-cancerous) tumors or cancer. It may help make treatments feel easier for you and your child during procedures.
Saint-DenisAges 6–18 - NCT03867539RecruitingPhase 4
Numbing shot and education to reduce opioids after carpal tunnel surgery
This study tests whether giving a long-lasting numbing injection (Exparel) plus education about pain management can help people avoid taking opioid pain pills after carpal tunnel release surgery. It may help reduce opioid use while still supporting comfort during recovery.
Dayton, OhioAges 18 years+ - NCT03834818Recruiting
Using a phone app to track pain after orthopedic surgery
This study collects information about pain and recovery after planned (elective) orthopedic surgery. It uses a smartphone to help understand outcomes and pain levels so care may improve.
Durham, North CarolinaAges 18–90 - NCT03353584Recruiting
Virtual reality for pain relief during sickle cell pain crises
This trial tests whether a virtual reality (VR) experience can help reduce pain during a sickle cell “vaso-occlusive crisis,” which is an episode of sudden, severe pain. It’s offered alongside the care team’s usual pain management to see if VR makes pain feel better.
Memphis, TennesseeAges 6–25 - NCT03365908Enrolling by invitation
Pain Management After ACL Reconstruction Surgery
This study looks at ways to manage pain in adults who are getting surgery to repair a torn ACL (a knee ligament). It may help improve comfort and recovery after ACL reconstruction.
Sacramento, CaliforniaAges 18–45 - NCT06097091Recruiting
Pain education for fibromyalgia patients
This trial tests if learning about how your brain and nerves process pain can help reduce fibromyalgia symptoms. You will attend sessions that teach you about the science of pain and how to manage it better.
TaipeiAges 18–64 - NCT07101172Enrolling by invitation
Stress ball for anxiety and pain during prostate biopsy
This study tests whether using a stress ball during a prostate biopsy can help reduce anxiety and pain. It may be an option if you are having your first biopsy and can squeeze a ball.
Çorum, MerkezAges 18 years+ - NCT06969456Recruiting
Exercise and nerve stimulation for chronic back pain
This study looks at whether combining exercise with a type of nerve stimulation (called neuromodulation) can help people with long-term spinal pain that has nerve involvement. It may be an option if you have had pain for at least 6 months and it is severe.
Valencia, ValenciaAges 18–70 - NCT07547371Recruiting
Aromatherapy and Digital Anesthesia for Dental Anxiety in Children
This study tests whether aromatherapy (calming scents) and digital anesthesia (numbing technology) can help reduce anxiety and pain when children need a baby molar removed. The goal is to find gentler ways to keep children comfortable during dental procedures.
Istanbul, IstanbulAges 6–12 - NCT07558278RecruitingPhase 4
LINQ procedure vs standard care for sacroiliac joint pain
This study compares a new procedure called LINQ—which stabilizes the sacroiliac joint (the joint where your spine connects to your pelvis)—against standard pain management for chronic sacroiliac joint pain. The trial tests whether this procedure reduces pain and disability better than medications and physical therapy alone.
Shenandoah, TexasAges 21 years+
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Common questions
- Are there clinical trials for pain management?
- Yes. Clin2 currently lists 338 recruiting pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.