Clinical trials
Pain Management clinical trials
Below are recruiting pain management clinical trials, each written for real people, not researchers. We’re tracking 338 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07153653Recruiting
Managing pregnancy pain with Baduanjin exercise
This trial tests whether a gentle mind-body exercise called Baduanjin can help reduce pain during pregnancy. If you are between 14 and 20 weeks pregnant with one baby and have no medical problems that prevent exercise, you may be able to join.
Beijing, Beijing MunicipalityAges 18–45 - NCT06913270Recruiting
Virtual reality for pain during burn dressing changes
This study tests whether using virtual reality (VR) during dressing changes can help reduce pain and anxiety for adults with burn injuries. If you have moderate to severe pain during dressing changes, this approach might offer extra comfort without extra medication.
CairoAges 18–65 - NCT06603792Recruiting
Brain training for diabetic nerve pain
This study tests whether a brain training method called neurofeedback can help reduce nerve pain caused by diabetes. It may offer a new, non-drug way to manage pain.
OdenseAges 18–82 - NCT05645224Enrolling by invitation
Virtual reality for pain and anxiety during laser skin treatment
This study tests whether using virtual reality (VR) during a laser procedure for a skin condition helps children and teens feel less pain and anxiety. If you are having your first laser treatment, you might be able to use a VR headset to distract you during the procedure.
Columbus, OhioAges 5–25 - NCT07548567Recruiting
Nerve Block to Reduce Pain During Below-Knee Fracture Surgery
This study tests a nerve-blocking injection (numbing medicine around the femoral artery nerve in your groin area) to help reduce pain and blood pressure changes during below-knee fracture surgery when a tourniquet (pressure cuff) is used. The goal is to see if this approach makes surgery more comfortable and safer.
AthensAges 18 years+ - NCT07072468RecruitingPhase 2
Test of a gel for nerve pain after chemotherapy
This study tests a new gel (VMD-3866) applied to the skin to treat moderate nerve pain, numbness, or tingling caused by previous chemotherapy. It aims to see if the gel can safely reduce pain for people whose symptoms have been stable for at least 8 weeks.
London, UKAges 18–80 - NCT07194967Enrolling by invitation
Virtual Reality for Pain Relief During Labor
This trial tests whether using virtual reality can help reduce pain and anxiety during labor. If you are having a low-risk pregnancy and plan a vaginal delivery, you may be able to use a VR headset during contractions to distract from pain.
Ben ArousAges 18–45 - NCT07328256Recruiting
Comparing two muscle relaxation techniques for neck pain relief
This study looks at two different gentle stretching methods to see which works better for relieving neck pain. It might help if you have had neck pain for a while and it limits your movement.
Islamabad, Punjab ProvinceAges 19–44 - NCT07361692Recruiting
Electric brain stimulation for complex regional pain syndrome
This trial tests if a gentle electric current applied to the scalp (called tDCS) can reduce pain in people with Complex Regional Pain Syndrome (CRPS), a chronic pain condition. It aims to see if this treatment is effective and safe for managing symptoms.
Saint-NazaireAges 18 years+ - NCT07434427RecruitingPhase 4
Buprenorphine vs. oxycodone for pain after lung surgery
This study compares two common pain medicines given through a patient-controlled pump after lung surgery done with small incisions. The goal is to see which one works better and has fewer side effects.
Zabrze, Silesian VoivodeshipAges 18–75 - NCT05767619Recruiting
Digital tool to guide care for chest pain calls
This trial tests a digital decision-support tool that helps emergency teams manage people who call for help because of chest pain. It may improve how safely and consistently chest pain is assessed and treated in the ambulance setting.
Kungsbacka, Region HallandAges 18 years+ - NCT04730700Recruiting
Radiofrequency treatment test for facet back pain
This study compares a nerve procedure (radiofrequency “neurotomy” using an expandable electrode) to non-procedure medical care for long-lasting low back pain from facet joints. It aims to see whether the procedure helps more safely than conservative treatment.
Kansas City, KansasAges 18 years+ - NCT06774274RecruitingPhase 4
Ketamine for pain after major orthopedic surgery: drip vs. pump
This study tests two ways of giving a medicine called ketamine to control pain after major bone or joint surgery. One method is a steady infusion (drip) through a vein, and the other is a patient-controlled pump (PCA) that lets you press a button for more medicine when you need it.
Medellín, AntioquiaAges 18 years+ - NCT07523802Recruiting
Managing pain after gum graft surgery with two methods
This trial tests two different ways to protect and manage pain in the mouth after a gum graft surgery. You would compare a product called Ora-Aid with a custom acrylic stent (a protective cover) to see which helps with healing and reduces discomfort better.
CairoAges 18 years+ - NCT07600892Enrolling by invitation
Pain-at-Work Toolkit for managing chronic pain at work
This study tests a toolkit designed to help working adults manage chronic pain while on the job. The toolkit aims to make work more manageable and enjoyable for people living with ongoing pain.
Nottingham, NottinghamshireAges 18 years+ - NCT07857655RecruitingPhase 4
Intraoperative methadone for pain after head and neck cancer surgery
This trial tests whether giving methadone during your head and neck cancer surgery helps control pain right after the operation. Methadone is a long-acting painkiller that might reduce pain for up to a day or more, potentially improving your recovery experience.
Portland, OregonAges 18–89 - NCT06509087Recruiting
Combining CT and MRI for joint pain procedure
This study tests a procedure called transarterial microembolization for chronic shoulder or knee pain that hasn't improved with other treatments. It uses both CT and MRI to guide the procedure and see if it can help reduce pain.
TaipeiAges 20–80 - NCT07683468Recruiting
A self-help kit for pain during sex with endometriosis
This trial tests if a special kit you can use at home helps reduce sexual pain caused by endometriosis. It might offer a new way to manage this common symptom.
StainsAges 18–45 - NCT07500012Recruiting
Ear nerve stimulation for breast cancer pain
This study tests whether gentle electrical stimulation of a nerve in your ear (called taVNS) can help reduce pain and improve symptoms for breast cancer survivors. You would need to have finished your main treatments, have ongoing pain, and be willing to provide stool samples and undergo brain scans.
Tallahassee, FloridaAges 18–79 - NCT06265636Recruiting
Nerve stimulation for jaw pain and function in TMD
This trial tests whether gentle electrical stimulation of a nerve in your jaw can reduce pain and improve chewing, talking, and mouth opening for people with temporomandibular joint disorder (TMD).
Alcorcón, MadridAges 18–65 - NCT06728579RecruitingPhase 2
Group therapy for joint pain in breast cancer survivors
This study tests two supportive group programs—one using mindfulness skills, the other providing supportive talk therapy—to help breast cancer survivors manage joint pain caused by hormone-blocking pills. If you have ongoing joint pain and are taking an aromatase inhibitor, you may be able to join a free, video-based group.
San Diego, CaliforniaAges 18 years+ - NCT04691037Recruiting
CT heart scan to guide care for stable chest pain
This trial studies whether a CT heart scan (CCTA) can better guide treatment decisions for people with stable chest pain caused by blocked heart arteries. It may help your care team choose the next best step based on scan results.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07835191Recruiting
Cooling and sweet solution to ease dental shot pain in children
This study tests whether cooling the injection site and using a sweet-tasting solution before the dental numbing shot can reduce pain for children aged 7 to 11. If your child needs a dental procedure requiring a local anesthetic injection, this might help make the experience more comfortable.
Cairo, El SheroukAges 7–11 - NCT07847541RecruitingPhase 2
Botulinum toxin injections for jaw muscle pain
This trial tests whether botulinum toxin (Botox) injections can reduce pain in the jaw muscles for people with temporomandibular joint (TMJ) disorders that haven't improved with other treatments. It may help if you have ongoing jaw pain and muscle tightness.
IslamabadAges 18–60
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Common questions
- Are there clinical trials for pain management?
- Yes. Clin2 currently lists 338 recruiting pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.