Clinical trials
Pain Management clinical trials
Below are recruiting pain management clinical trials, each written for real people, not researchers. We’re tracking 349 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07561827RecruitingPhase 3
Nerve Block for Pain After Spine Surgery in Teens
This trial tests whether a numbing injection around the spine muscles (erector spinae plane block) reduces pain and the need for strong pain medications after back surgery for scoliosis in teenagers. The goal is to help young patients recover more comfortably.
San Francisco, CaliforniaAges 10–18 - NCT07603323Recruiting
Pain Relief Methods for Meniscus Knee Surgery
This study compares two different numbing techniques (ACB and ACB combined with BiFeS) to see which one better controls pain after meniscus surgery. The meniscus is cartilage in your knee that can tear and cause pain.
AnkaraAges 18–65 - NCT07663266Recruiting
Pain management study for MS or spinal cord injury
This study tests a smartphone-based program to help manage chronic pain in people with multiple sclerosis or spinal cord injury. It involves virtual interviews or focus groups to design a tool that offers personalized pain management tips.
Ann Arbor, MichiganAges 18 years+ - NCT07606638Enrolling by invitation
Pain Relief Options for Oral Cancer Patients
This study compares two different pain management approaches for people with oral cancer: opioid medication versus a combination of pregabalin (a nerve pain reliever) and naproxen sodium (an anti-inflammatory painkiller). The goal is to see which approach works better and is safer for controlling cancer-related pain.
Lahore, Punjab ProvinceAges 18 years+ - NCT07432074Enrolling by invitation
Acupressure and massage after cesarean section
This study tests whether acupressure (gentle pressure on specific points) or massage can help women recover after a planned cesarean. It aims to reduce pain and improve comfort without using extra medicine.
IstanbulAges 18–45 - NCT07368738Enrolling by invitationPhase 4
IV Pain Meds for Shock Wave Lithotripsy
This study tests whether giving two pain relievers—acetaminophen (Tylenol) and ketorolac (an anti-inflammatory)—through an IV during shock wave lithotripsy helps control pain better than standard care. You may qualify if you need this kidney stone procedure and don't have certain health conditions.
Saint John, New BrunswickAges 19 years+ - NCT07215546Enrolling by invitation
Stopping pain after heart surgery with a special chest closure
This trial tests a new device to close the breastbone after open-heart surgery to see if it helps reduce the need for prescription pain medicine. The device is designed to hold the bone together more securely, which may lead to less pain and faster recovery.
Naples, FloridaAges 19–80 - NCT05964868Enrolling by invitationPhase 3
Liposome anesthesia to reduce pain after nose surgery
This Phase 3 study tests whether a special form of local numbing medicine (liposomal bupivacaine) helps reduce pain after septorhinoplasty (nose and septum surgery). You may be considered if you’re planning this surgery and can follow study instructions before and after.
Hershey, PennsylvaniaAges 18–99 - NCT05705128Enrolling by invitationPhase 2/Phase 3
Dexmedetomidine to help pain after shoulder surgery
This trial studies whether dexmedetomidine can reduce pain after elective shoulder arthroscopy surgery done under general anesthesia. If you’re eligible, it may help improve postoperative comfort and reduce the need for additional pain treatment.
AsyutAges 18–60 - NCT06097091Recruiting
Pain education for fibromyalgia patients
This trial tests if learning about how your brain and nerves process pain can help reduce fibromyalgia symptoms. You will attend sessions that teach you about the science of pain and how to manage it better.
TaipeiAges 18–64 - NCT06100822RecruitingPhase 1
Testing metformin for chronic Achilles tendon pain
This study tests whether a common diabetes medication, metformin, can help people with chronic Achilles tendon pain. If you have this condition and meet certain health requirements, you may be able to join.
Pittsburgh, PennsylvaniaAges 18–50 - NCT07101172Enrolling by invitation
Stress ball for anxiety and pain during prostate biopsy
This study tests whether using a stress ball during a prostate biopsy can help reduce anxiety and pain. It may be an option if you are having your first biopsy and can squeeze a ball.
Çorum, MerkezAges 18 years+ - NCT06969456Recruiting
Exercise and nerve stimulation for chronic back pain
This study looks at whether combining exercise with a type of nerve stimulation (called neuromodulation) can help people with long-term spinal pain that has nerve involvement. It may be an option if you have had pain for at least 6 months and it is severe.
Valencia, ValenciaAges 18–70 - NCT07547371Recruiting
Aromatherapy and Digital Anesthesia for Dental Anxiety in Children
This study tests whether aromatherapy (calming scents) and digital anesthesia (numbing technology) can help reduce anxiety and pain when children need a baby molar removed. The goal is to find gentler ways to keep children comfortable during dental procedures.
Istanbul, IstanbulAges 6–12 - NCT07558278RecruitingPhase 4
LINQ procedure vs standard care for sacroiliac joint pain
This study compares a new procedure called LINQ—which stabilizes the sacroiliac joint (the joint where your spine connects to your pelvis)—against standard pain management for chronic sacroiliac joint pain. The trial tests whether this procedure reduces pain and disability better than medications and physical therapy alone.
Shenandoah, TexasAges 21 years+ - NCT07153653Recruiting
Managing pregnancy pain with Baduanjin exercise
This trial tests whether a gentle mind-body exercise called Baduanjin can help reduce pain during pregnancy. If you are between 14 and 20 weeks pregnant with one baby and have no medical problems that prevent exercise, you may be able to join.
Beijing, Beijing MunicipalityAges 18–45 - NCT06603792RecruitingEarly Phase 1
Neurofeedback for diabetic nerve pain
This trial tests whether a brain-training technique called neurofeedback can help reduce nerve pain caused by diabetes. It is for people with type 1 or type 2 diabetes who have had moderate-to-severe nerve pain for at least 3 months.
OdenseAges 18–82 - NCT06913270Recruiting
Virtual reality for pain during burn dressing changes
This study tests whether using virtual reality (VR) during dressing changes can help reduce pain and anxiety for adults with burn injuries. If you have moderate to severe pain during dressing changes, this approach might offer extra comfort without extra medication.
CairoAges 18–65 - NCT07548567Recruiting
Nerve Block to Reduce Pain During Below-Knee Fracture Surgery
This study tests a nerve-blocking injection (numbing medicine around the femoral artery nerve in your groin area) to help reduce pain and blood pressure changes during below-knee fracture surgery when a tourniquet (pressure cuff) is used. The goal is to see if this approach makes surgery more comfortable and safer.
AthensAges 18 years+ - NCT06809543Recruiting
Testing Tropho Tend for painful rotator cuff tendinopathy
This study tests a product called Tropho Tend to see if it safely reduces pain and improves function in people with rotator cuff tendinopathy, a condition where the shoulder tendons are sore and irritated. If you have had shoulder pain for at least 6 weeks and it is at least a 4 on a 10-point scale, this trial might be a good fit.
Sassuolo, ItalyAges 18 years+ - NCT07072468RecruitingPhase 2
Test of a gel for nerve pain after chemotherapy
This study tests a new gel (VMD-3866) applied to the skin to treat moderate nerve pain, numbness, or tingling caused by previous chemotherapy. It aims to see if the gel can safely reduce pain for people whose symptoms have been stable for at least 8 weeks.
London, UKAges 18–80 - NCT07194967Enrolling by invitation
Virtual Reality for Pain Relief During Labor
This trial tests whether using virtual reality can help reduce pain and anxiety during labor. If you are having a low-risk pregnancy and plan a vaginal delivery, you may be able to use a VR headset during contractions to distract from pain.
Ben ArousAges 18–45 - NCT07328256Recruiting
Comparing two muscle relaxation techniques for neck pain relief
This study looks at two different gentle stretching methods to see which works better for relieving neck pain. It might help if you have had neck pain for a while and it limits your movement.
Islamabad, Punjab ProvinceAges 19–44 - NCT07361692Recruiting
Electric brain stimulation for complex regional pain syndrome
This trial tests if a gentle electric current applied to the scalp (called tDCS) can reduce pain in people with Complex Regional Pain Syndrome (CRPS), a chronic pain condition. It aims to see if this treatment is effective and safe for managing symptoms.
Saint-NazaireAges 18 years+
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Common questions
- Are there clinical trials for pain management?
- Yes. Clin2 currently lists 349 recruiting pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.