Clinical trials
Pain Management clinical trials
Below are recruiting pain management clinical trials, each written for real people, not researchers. We’re tracking 339 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07256145Recruiting
Ultrasound-guided nerve block for post-shingles pain
This study compares a new ultrasound-guided nerve block (erector spinae plane block) with standard care to help manage stubborn nerve pain after shingles. It might be an option if usual medications havent helped your pain.
Alexandria, AleexandriaAges 20–70 - NCT07242170Recruiting
Comparing nerve blocks for pain after knee replacement surgery
This trial tests if adding extra nerve blocks (sciatic, BiFeS, or IPACK) to the usual adductor canal block can reduce pain after total knee replacement. The goal is to find a better way to manage pain and improve recovery.
Erzincan, MerkezAges 18–75 - NCT07232108Recruiting
Pain medicine options for recovery after laparoscopic hysterectomy
This study compares two types of pain medicine given during laparoscopic hysterectomy: one is a morphine shot into the spine, the other is numbing medicine injected around the surgery cuts and into the belly. The goal is to see which helps you recover better and with less pain.
ErzurumAges 18–65 - NCT06913920Recruiting
Comparing therapies for hand swelling and pain after wrist fracture surgery
This trial tests whether using mechanical devices (like compression or massage) reduces swelling and pain better than standard care after wrist fracture surgery. It may help you recover hand function more comfortably.
CairoAges 18–65 - NCT07215546Enrolling by invitation
Stopping pain after heart surgery with a special chest closure
This trial tests a new device to close the breastbone after open-heart surgery to see if it helps reduce the need for prescription pain medicine. The device is designed to hold the bone together more securely, which may lead to less pain and faster recovery.
Naples, FloridaAges 19–80 - NCT07218133Recruiting
Ear Stimulation to Reduce Pain After Spine Surgery
This trial tests whether a gentle electrical stimulation delivered through the ear can reduce inflammation and pain after major spinal fusion surgery. If you are having a long spinal fusion, you might be able to join.
St Louis, MissouriAges 18 years+ - NCT07208799RecruitingPhase 2
Steroid comparison for jaw fracture recovery
This trial compares two steroid medicines (dexamethasone and methylprednisolone) to see which one better reduces swelling, pain, and other symptoms after surgery for a broken lower jaw near the chin. It could help you recover faster and with less discomfort.
Multan, Punjab ProvinceAges 18–40 - NCT07185594RecruitingPhase 2/Phase 3
Study of a new pain drug after abdominal surgery
This trial tests a new medication called HRS-2129 for managing pain after abdominal surgery. It is for adults who will have moderate to severe pain after their operation, and aims to see if the drug can help control that pain safely.
Zhengzhou, HenanAges 18 years+ - NCT07176494Recruiting
Revision of Deep Brain Stimulator in Parkinson's Disease
This study is for people with Parkinson's disease who need to have their deep brain stimulator (a device that sends electrical pulses to control movement) replaced or adjusted. The researchers want to learn the best way to do this procedure safely.
Ankara, Yenimahalle\AnkaraAges 40–85 - NCT07172984Recruiting
Can breathing exercises help during joint injections?
This study tests whether paying attention to your breathing during an ultrasound-guided joint injection helps you feel more comfortable. It could make the procedure easier for you.
ChambéryAges 18 years+ - NCT05525923Recruiting
Personalized pain plan after chest surgery in adults
This trial tests a personalized (tailored) plan to manage pain after thoracic (chest) surgery. It may help improve comfort and recovery by matching pain treatment to your situation after surgery.
Pittsburgh, PennsylvaniaAges 18–99 - NCT05452694Recruiting
Personalized pain relief after back fusion surgery
This trial tests a personalized plan to manage pain after lumbar (lower back) fusion and decompression surgery. It may help reduce difficult pain while guiding safe use of opioids around the time of surgery.
Pittsburgh, PennsylvaniaAges 18–99 - NCT07151443Recruiting
Comparing two ways to numb the arm for hand surgery in people with obesity
This study compares two ways of numbing the arm for forearm or hand surgery in people who are obese. One method places the numbing medicine near the collarbone from the front, and the other from behind the collarbone. The goal is to see which way works better.
Yenimahalle, AnkaraAges 18–80 - NCT07147062Recruiting
Pain relief after hernia surgery in children
This trial compares two types of pain blocks (rectus sheath block or caudal epidural block) used in children having a specific hernia surgery. It aims to see which block works better for controlling pain after the procedure.
Altındağ, AnkaraAges 1–8 - NCT07123740Recruiting
Pain relief after liver donor surgery: two methods compared
This study compares two ways to control pain after surgery for living liver donors. It tests if one method works better than the other, which could help you recover more comfortably.
Altındağ, AnkaraAges 18–65 - NCT07113483RecruitingPhase 3
Remimazolam vs. Midazolam for sedation in older adults having orthopedic surgery
This trial compares two sedatives, remimazolam and midazolam, to see which one leads to better recovery of thinking skills after orthopedic surgery. It is for people aged 65 and older who are having surgery on a bone or joint while awake but relaxed.
BucharestAges 65 years+ - NCT06966869Recruiting
Fentanyl patch absorption in ICU patients
This study looks at how well fentanyl patches work in ICU patients who are not stable. It aims to understand if the patch is absorbed properly in these patients.
Tel Aviv, IsraelAges 18–70 - NCT07092566RecruitingPhase 3
Pain relief after robotic kidney surgery: R.E.C.K. vs Exparel
This trial tests two different pain-relief medicines (R.E.C.K. and Exparel) given during robotic kidney surgery. It aims to find which works better to control pain after the operation.
Charlotte, North CarolinaAges 18 years+ - NCT07095556Recruiting
Laser therapy to help gums heal after tooth extraction
This trial tests whether a special laser treatment can help your gums heal better after a tooth is removed and the socket is prepared for a future dental implant. If you're having a tooth pulled and bone preservation, this laser might speed up healing and reduce pain.
Charleston, South CarolinaAges 18 years+ - NCT05779852Recruiting
Hypnosis to ease new foot amputation wound pain
This trial tests whether auto-hypnosis (a self-guided calming technique) can reduce pain after a toe or multiple toes are removed. It is for adults who are newly after an amputation and have moderate pain soon after the first dressing.
RennesAges 18 years+ - NCT07072286Recruiting
Regional anesthesia for pelvic fracture pain relief
This study tests whether regional anesthesia techniques, which numb the area around your pelvic fracture, can better manage your pain while you wait for surgery. It aims to see if these methods improve pain relief and reduce the need for other pain medicines.
TurinAges 18 years+ - NCT07070050RecruitingPhase 4
NSAIDs after laparoscopic surgery: continuous or bolus?
This study compares giving NSAID pain relievers continuously through an IV versus as single doses (bolus) after laparoscopic surgery to find which method provides better pain relief with fewer side effects.
Moscow, Moscow OblastAges 18 years+ - NCT07063602Recruiting
Comparing nerve block methods for pain after lung surgery
This study compares two ways of giving a paravertebral nerve block (an injection near the spine to numb the chest) to control pain after a type of lung surgery called VATS. It aims to find the best approach for reducing pain and the need for stronger pain medicines.
Montreal, QuebecAges 18 years+ - NCT07037888RecruitingPhase 4
Ketorolac for pain after hip arthroscopy
This study tests whether ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), helps manage pain after hip surgery. It may offer an opioid-sparing option for patients with femoroacetabular impingement (FAI).
Detroit, MichiganAges 18–89
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Common questions
- Are there clinical trials for pain management?
- Yes. Clin2 currently lists 339 recruiting pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.