Clinical trials
Pain, Nerve clinical trials
Below are recruiting pain, nerve clinical trials, each written for real people, not researchers. We’re tracking 224 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05272488Recruiting
Manual therapy plus vagus nerve stimulation for jaw muscle pain
This trial tests whether combining hands-on jaw treatment with a vagus nerve stimulator can reduce jaw muscle pain and improve jaw movement. It may help people whose jaw pain has been present recently and who have not had recent physiotherapy.
Alcalá de Henares, MadridAges 18 years+ - NCT06240260Recruiting
TENS unit for pain relief during IUD insertion
This study tests whether a small device called a TENS unit can reduce pain during IUD insertion. The TENS unit sends gentle electrical pulses through pads on your skin to help block pain signals, and you'll be part of a group that uses it during the procedure.
Boston, MassachusettsAges 12–50 - NCT07696312Recruiting
Straight leg raise test accuracy for leg pain
This study checks how well the straight leg raise test can find the exact nerve causing your leg pain by comparing it with a targeted nerve block injection. It may help if you have leg pain from a pinched nerve in your lower back.
Istanbul, PENDİKAges 18–65 - NCT06556121Recruiting
Numbing shot for gender-affirming surgery pain
This trial tests a numbing shot given during penile inversion vaginoplasty to see if it reduces pain after surgery. It might help people manage pain with less need for strong painkillers.
Toronto, OntarioAges 18–70 - NCT06574841Recruiting
Blood flow restriction therapy for carpal tunnel syndrome
This study tests a new hand therapy that uses a special band to lightly restrict blood flow while you do exercises. It may help reduce pain, improve grip strength, and nerve function in people with carpal tunnel syndrome.
CairoAges 30–55 - NCT06872437RecruitingPhase 3
Study of pudendal nerve injections for nerve pain treatment
This trial tests if a numbing injection into the pudendal nerve can reduce pain after one month. It's for people with pudendal neuralgia that hasn't improved with medication.
ParisAges 18 years+ - NCT06891690Recruiting
Brain stimulation for neurological and gynecological conditions
This trial tests whether a gentle brain stimulation technique called tDCS can help people with neurological problems (like weakness in arms or legs) or certain gynecological conditions (like endometriosis or painful periods) who are not using other treatments. It aims to see if tDCS can improve symptoms.
PoznanAges 18–90 - NCT06934421Recruiting
A new approach for knee radiofrequency ablation
This trial tests a revised method for radiofrequency ablation to treat chronic knee pain from severe osteoarthritis (KL grade III or IV). It aims to see if the procedure can help patients who haven't gotten relief from standard treatments like physical therapy, painkillers, and steroid injections.
FaroAges 18 years+ - NCT07605754Recruiting
Nerve Surgery Results for Pain After Amputation
This study evaluates how well nerve surgery works for patients with severe, persistent pain in the area where a limb was amputated. Researchers will review outcomes to understand if this surgical approach helps reduce pain that hasn't responded to other treatments.
Leiden, South HollandAges 18 years+ - NCT07011537Enrolling by invitation
Digital health program and TENS for chronic low back pain
This trial tests a digital health program combined with a TENS device (a small device that sends gentle electrical pulses to help with pain) for people with ongoing low back pain. It compares this approach to standard care, and you would be randomly assigned to one of the two groups.
Eden Prairie, MinnesotaAges 18 years+ - NCT05812885Recruiting
TENS for long-lasting low back pain
This study tests whether transcutaneous electrical nerve stimulation (TENS), a non-drug pain treatment using small electrode pads on the skin, can help people with low back pain. You may be eligible if your back pain has lasted at least 3 months and your pain is at least moderate.
West Hartford, ConnecticutAges 18–60 - NCT06570577Recruiting
Nerve block for pain after cervical spine surgery
This trial tests whether a nerve block can reduce the need for opioid pain medication after back-of-neck spine surgery. It may help patients have better pain control with fewer side effects.
Stony Brook, New YorkAges 18–75 - NCT07568015Recruiting
Nerve-targeted treatment for lateral hip pain
This study tests an experimental treatment that targets nerves around the hip to relieve pain on the outside of the hip. It may help people who have tried other treatments without enough relief.
Sun City, ArizonaAges 22–80 - NCT07296926Recruiting
Numbing injection comparison for wisdom tooth removal
This study compares two numbing methods for removing a lower wisdom tooth. One is an injection near the tooth and the other is a nerve block. It aims to see which works better and may be more comfortable.
IslamabadAges 18–45 - NCT07049094RecruitingPhase 4
Scalp nerve block for pain after brain surgery
This trial tests if a long-lasting numbing medicine (bupivacaine liposomes) injected into scalp nerves can reduce pain after brain surgery. It may help you need less pain medicine and feel better after your operation.
Hangzhou, ZhejiangAges 18 years+ - NCT06873893Recruiting
Nerve blocks for pain relief after mastectomy surgery
This study compares two types of ultrasound-guided nerve blocks to see which one provides better pain relief after a mastectomy. The blocks are injected near the chest wall to numb the area during and after surgery.
Cairo , AbbassyaAges 35–65 - NCT06406010RecruitingPhase 4
Nerve block for pain after hip surgery
This trial tests whether a specific nerve block can reduce pain after a hip socket surgery. The results could help improve recovery and reduce the need for strong painkillers.
CopenhagenAges 18 years+ - NCT07287657Enrolling by invitation
Electrical acupoint stimulation after chest surgery
This trial tests a gentle, non-needle therapy that stimulates acupoints with mild electrical current to help you recover better after chest surgery. It may reduce pain and speed healing.
Taipei, HualienAges 15 years+ - NCT07134660Recruiting
Comparing two numbing medicines for lung surgery pain
This study compares two types of numbing medicine (liposomal vs. hydrochloride bupivacaine) injected near the ribs during lung surgery. The goal is to see which one provides better pain relief after the operation.
ShanghaiAges 18–80 - NCT06450483Recruiting
Acupuncture for neck pain in college athletes
This study tests whether a type of acupuncture (called auricular vagus nerve stimulation, or AVNS) can help college athletes with neck pain. It looks at how the treatment affects pain, balance, and heart rate. If you’re a healthy college athlete with mild to moderate neck pain and no recent injuries, you may be a good fit.
Sharjah cityAges 18–26 - NCT07304076Recruiting
JHG002 Injection for Chronic Low Back Pain
This study tests if JHG002 injections (made from human placenta) are safe and effective for treating chronic low back pain. It may help people who have had low back pain for at least 6 months and rate their pain as a 5 or higher on a 0–10 scale.
Seoul, Gangdong-guAges 19–70 - NCT06529432RecruitingPhase 2
Study of a long-acting painkiller for lung surgery recovery
This trial tests a long-acting pain medication (bupivacaine liposome injection) to control pain after lung surgery done through a small cut. It may help you feel more comfortable and reduce the need for other pain medicines.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07388953Recruiting
Nerve block for better pain relief after colon surgery
This study tests adding a special nerve block (peripheral autonomic block) to a standard abdominal wall block to see if it provides better pain relief after minimally invasive left-sided colon surgery. It may help patients experience less pain and use fewer pain medications.
Belo Horizonte, Minas GeraisAges 18–80 - NCT07496398Recruiting
Nerve function study in tattoo artists
This study looks at how tattooing may affect the nerves in the arm and hand. It compares tattoo artists to healthy people to see if the vibrations from tattoo machines cause any changes in nerve function.
AnkaraAges 18 years+
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Common questions
- Are there clinical trials for pain, nerve?
- Yes. Clin2 currently lists 224 recruiting pain, nerve studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain, nerve trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain, nerve trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.