Clinical trials
Pain Perception clinical trials
Below are recruiting pain perception clinical trials, each written for real people, not researchers. We’re tracking 29 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06841601Recruiting
Shaking or cold for less pain during dental shots
This trial tests whether a vibrating tool or a cold pack can help reduce pain when children get a numbing shot at the dentist. If your child needs a simple filling and is generally healthy, this study might help make their experience more comfortable.
AlexandriaAges 5–9 - NCT07148921Recruiting
Pain perception during gender affirming hormone therapy
This study looks at how starting gender affirming hormone therapy may change your experience of pain. If you are an adult assigned female at birth planning to start testosterone, or an adult assigned male at birth planning to start estradiol, and you have not taken any sex hormones in the past six months, this trial wants to measure your pain perception over time.
Vienna, State of ViennaAges 18 years+ - NCT06659731Recruiting
Pain testing in children with autism
This study measures how children with autism experience pain using simple tests like warmth or pressure. It helps researchers understand sensory differences in autism.
Brindisi, BRAges 5–17 - NCT02446262Recruiting
Study of how the brain and mind shape pain in healthy adults
This study tests how people sense heat and pain, and how the brain and emotions may influence that experience. It is designed for healthy adults and may involve training sessions and (for some parts) MRI scanning.
Bethesda, MarylandAges 18–50 - NCT06706037Recruiting
Reformer exercise for chronic muscle and joint pain
This study tests if Reformer Pilates exercises can reduce pain for people with long-term muscle or joint pain. It may help you feel better and move more easily.
Ankara, Select StateAges 30–50 - NCT02821741Recruiting
Testing ear stimulation effects on pain and mood
This study tests whether stimulating the outside of your ear changes how you feel pain and how your mood/feelings are measured. It’s mainly testing a non-drug, ear-based approach and whether it affects pain signals.
Bethesda, MarylandAges 18–50 - NCT07525895Enrolling by invitation
Nerve Stretching for Lower Leg Pain Relief
This study tests whether gentle stretching exercises targeting the sciatic nerve (a major nerve in your leg) can help reduce leg pain and improve how your body perceives pain. Researchers will compare this treatment to standard care to see if it works.
Istanbul, AtaşehirAges 18–30 - NCT03446456RecruitingPhase 1/Phase 2
Vasopressin and pain perception study
This trial tests whether vasopressin, a nasal spray, changes how your brain processes pain. You will receive either the spray or a placebo and have an MRI scan to see brain activity.
Baltimore, MarylandAges 18–65 - NCT05458037Recruiting
Testing fast versus slow numbing during IUD or biopsy
This study compares two ways of applying a numbing tool (“tenaculum”) during an IUD insertion or an endometrial biopsy to see which one causes less pain. If you’re scheduled for one of these procedures, it may help improve how discomfort is managed.
Providence, Rhode IslandAges 18 years+ - NCT07650591Recruiting
Tapping and vibration to ease needle pain in children
This study tests whether rhythmic tapping and gentle vibration near the skin can help children ages 6–12 feel less pain and fear during blood draws. Researchers want to see if these simple techniques can make the procedure more comfortable.
Antalya, KepezAges 6–12 - NCT05919745RecruitingPhase 4
Ibuprofen before mouth surgery to reduce pain sensing
This trial studies whether taking ibuprofen before tooth extraction and bone graft surgery can lower how much pain you feel afterward. It may help by changing the body’s pain response during healing.
Milwaukee, WisconsinAges 18 years+ - NCT06510244Recruiting
Measuring pain during dental treatment with brain waves
This trial uses EEG (a brain-wave test) and a pain scale to measure how much discomfort you feel during dental treatment on your upper front tooth. It may help dentists understand pain better and improve care.
Cleveland, OhioAges 20–60 - NCT07467551Recruiting
Pain scale study for patients on breathing machines
This study tests a pain scale for patients who are on a breathing machine and cannot speak. It aims to help doctors better recognize pain in these patients.
IstanbulAges 18–85 - NCT06506708Recruiting
Massage and hydrotherapy for endometriosis pain
This study tests whether combining massage and water therapy can reduce pain and improve well-being in people with endometriosis. If you have had pelvic pain for at least 6 months, this trial might help you find relief.
GranadaAges 18–55 - NCT06984796Enrolling by invitation
Light therapy for pain during IUD insertion
This study tests if light therapy (photobiomodulation) can reduce pain when an IUD is inserted. It might help women who are anxious about pain during the procedure.
São PauloAges 18–50 - NCT06357715Recruiting
Nerve stretching in healthy adults: pain threshold study
This study tests a gentle nerve stretching technique (called 'slump neurodynamic mobilization') in healthy adults to see if it changes how they sense pain. Researchers want to learn how much pressure feels uncomfortable before and after the exercise.
RouenAges 30–65 - NCT06974474RecruitingPhase 4
Guselkumab for pain in psoriatic arthritis
This study tests if guselkumab can reduce pain and inflammation in people with psoriatic arthritis. You may join if standard treatments have not worked well enough or caused side effects.
Rome, ItalyAges 18–80 - NCT07177027Recruiting
Breathing exercises and music for first-time mothers in labor
This study tests whether combining breathing exercises with listening to music during labor can help first-time mothers feel less pain, have more positive expectations, and feel more satisfied with their birth experience. If you join, you will practice breathing techniques and listen to music while in labor.
Uşak, UşakAges 18–35 - NCT06574841Recruiting
Blood flow restriction therapy for carpal tunnel syndrome
This study tests a new hand therapy that uses a special band to lightly restrict blood flow while you do exercises. It may help reduce pain, improve grip strength, and nerve function in people with carpal tunnel syndrome.
CairoAges 30–55 - NCT07447193Recruiting
Pain perception by gender in adults with scoliosis
This study looks at how men and women with scoliosis experience pain differently. It involves questionnaires and simple movement tests to understand pain patterns.
BakuAges 18–45 - NCT07167394Enrolling by invitation
Virtual reality glasses for kids' dental pain relief
This trial tests whether virtual reality (VR) goggles can reduce pain during dental treatment in children aged 6 to 10 who have never been to the dentist before and have a cavity in a back tooth.
Ankara, YenimahalleAges 6–10 - NCT06571006Enrolling by invitation
Music therapy for pain relief during spinal tap in babies
This study tests whether playing gentle music during a lumbar puncture (a spinal tap) can help lower a baby's pain. It's for newborn infants who need this procedure and have normal hearing.
ErzurumAges 1 month–1 month - NCT06944314Enrolling by invitation
Doctors' views on pain during flexible cystoscopy with local anesthetic
This trial asks doctors to rate how much pain they think male patients feel during a minimally invasive bladder exam. It aims to see if doctors' estimates of pain are accurate.
Istanbul, IstanbulAges 18 years+ - NCT06785909Recruiting
Understanding why pregnancy back and pelvic pain persists
This study looks at why some women develop ongoing pain in the lower back or pelvis during pregnancy. It tests how your body's sense of movement, fear of pain, and inflammation might be related. You may join if you are early in a single pregnancy and do not have that pain yet.
HasseltAges 18–40
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Common questions
- Are there clinical trials for pain perception?
- Yes. Clin2 currently lists 29 recruiting pain perception studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain perception trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain perception trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.