Clinical trials
Parkinson Disease Dementia clinical trials
Below are recruiting parkinson disease dementia clinical trials, each written for real people, not researchers. We’re tracking 315 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05700825RecruitingPhase 2
Rehab training to improve swallow safety in Parkinson’s
This trial tests a rehabilitation approach aimed at improving airway protection during swallowing in people with Parkinson’s disease. It may help reduce the risk of food or liquid going down the wrong way by improving swallow safety.
West Lafayette, IndianaAges 50–90 - NCT05680597Recruiting
Video balance rehab program for Parkinson’s symptoms
This trial tests a 4-week, at-home video rehabilitation program focused on balance problems in people with Parkinson’s disease. It aims to see whether this tele-rehab approach helps with walking and stability while keeping medications steady.
Portland, OregonAges 55–85 - NCT05644327Recruiting
Exercise program to improve sleep in Parkinson’s disease
This study looks at whether an exercise program can improve sleep problems in people with Parkinson’s disease. It’s mainly for those who already have poor sleep quality while taking stable Parkinson’s medicine.
Laval, QuebecAges 40 years+ - NCT05268887Recruiting
Light, sound, and touch therapy for Parkinson’s symptoms
This trial tests whether high-frequency light, sound, and gentle touch can improve movement and thinking problems in people with Parkinson’s disease. You may help the researchers learn if this kind of stimulation is safe and beneficial alongside your usual Parkinson’s medications.
Cambridge, MassachusettsAges 45–90 - NCT04731246Recruiting
Eye-movement testing in people with early Parkinson’s
This study uses video recordings of your eye movements to learn more about Parkinson’s disease. It may help researchers better tell Parkinson’s apart from other movement conditions and understand how the disease affects the brain early on.
MonacoAges 18 years+ - NCT04496973Recruiting
Parkinson’s disease research registry for adults
This registry asks people with Parkinson’s disease to join a research program at the University of Delaware. Being in the registry may help you get invited to investigator-led studies that could improve understanding or treatment of Parkinson’s.
Newark, DelawareAges 21–100 - NCT07734181Recruiting
Music Therapy for Parkinson's Disease
This trial tests whether music therapy can help people with Parkinson's disease. It might improve movement, mood, or quality of life.
Arlesheim, Basel-LandschaftAges 50–79 - NCT07730073Recruiting
LSVT-LOUD therapy for voice and speech in Parkinson's disease
This study tests whether LSVT-LOUD, a speech therapy program, can improve voice, speech, and quality of life in people with Parkinson's disease who have voice or speech problems. Participants must be native Turkish speakers, aged 40-80, with mild to moderate Parkinson's.
Kâğıthane, IstanbulAges 40–80 - NCT07606547Recruiting
Swallowing Strength Training for Parkinson's Disease
This study tests whether a mouth and throat muscle-strengthening device called EMST helps people with Parkinson's disease who have difficulty swallowing. Stronger throat muscles may make swallowing safer and easier.
MünsterAges 18 years+ - NCT07569133Enrolling by invitation
Brain stimulation for depression in Parkinson's disease
This study tests whether a non-invasive brain stimulation treatment called repetitive transcranial magnetic stimulation (rTMS) can help improve depressive symptoms in people with Parkinson's disease. If you have Parkinson's and feel depressed, this treatment might be a new option for you.
Daegu, Buk-guAges 40–90 - NCT06742450Recruiting
Comparing two ways to stimulate the brain for Parkinson's
This trial compares two methods of deep brain stimulation (constant current vs constant voltage) for people with Parkinson's who already have the device placed but haven't turned it on yet. The goal is to see which method works better.
BeijingAges 18–75 - NCT07244640Recruiting
Detecting Parkinson's through eye scans
This study uses a special eye camera to see if early signs of Parkinson's and similar movement disorders can be spotted in the retina. It may help doctors diagnose these conditions sooner and more easily.
Hangzhou, ZhejiangAges 40–80 - NCT07100171RecruitingEarly Phase 1
GM101 injection for advanced Parkinson's disease
This trial tests an investigational gene therapy injection called GM101 for people with advanced Parkinson's disease whose symptoms are not well controlled by standard medications. The study will see if this treatment can help improve movement and quality of life.
ChangshaAges 40–70 - NCT07064005RecruitingPhase 1
Boosting glutathione with a supplement in Parkinson's
This study tests whether a supplement called gamma-glutamylcysteine can increase levels of a natural antioxidant called glutathione in the brain of people with Parkinson's. If you are between 50 and 80 and have mild cognitive symptoms, this trial may help researchers understand a new way to support brain health.
Pittsburgh, PennsylvaniaAges 50–80 - NCT05968703Recruiting
Deep brain stimulation study for mild memory trouble in Parkinson’s
This trial looks at a specific type of deep brain stimulation (DBS) to see if it can help people with Parkinson’s who have mild cognitive problems (mild memory/thinking changes). You may also be asked to temporarily stop Parkinson’s medications around research visits to measure effects more clearly.
Stanford, CaliforniaAges 21–80 - NCT06891781Recruiting
Adaptive deep brain stimulation for Parkinson's
This study tests a new type of deep brain stimulation (DBS) that adapts to your brain activity in real time. It is for people with Parkinson's disease whose symptoms are not well managed by medication and who are already candidates for DBS surgery.
MonzaAges 18 years+ - NCT06874803Recruiting
Acupuncture and moxibustion for early Parkinson's motor symptoms
This trial tests whether acupuncture and moxibustion can help improve movement symptoms in people with early to moderate Parkinson's disease. It is designed to see if adding these treatments to your regular care offers extra benefits.
Beijing, Beijing MunicipalityAges 30–80 - NCT06857851Recruiting
Deep brain stimulation study for movement in Parkinson's
This study looks at whether adjusting deep brain stimulation (DBS) can improve how you see and move. DBS uses a device implanted in your brain to help control Parkinson's symptoms. This research aims to find better settings for that device to improve your coordination and daily function.
Cleveland, OhioAges Any age - NCT06753331RecruitingPhase 1/Phase 2
Study of DSP-1083 for Parkinson's disease
This trial tests a new treatment called DSP-1083 for people with Parkinson's disease whose symptoms are not well controlled with standard medications. The study will check if it is safe and if it helps improve movement and daily function.
Lexington, KentuckyAges 40–72 - NCT06701955Recruiting
Reliability of a Fluctuation Scale in Parkinson's
This study tests how consistently a new scale measures 'on-off' fluctuations in Parkinson's disease. If you experience motor fluctuations (times when your symptoms change) and are on stable medication, you may help validate this tool.
GrenobleAges 30–75 - NCT06442033Recruiting
Exercise and genetics to slow Parkinson's
This trial studies whether a regular aerobic cycling program can slow the progression of Parkinson's disease. Researchers will also look at how genetics may affect the benefits of exercise.
Cleveland, OhioAges 18 years+ - NCT06405334Recruiting
Balance and movement study for veterans with Parkinson's
This study looks at how Parkinson's disease affects balance and movement. It may help predict fall risk and improve care. Some participants also have a special brain device to help with movement.
Minneapolis, MinnesotaAges 18 years+ - NCT06402955RecruitingPhase 2
Imaging depression in Parkinson's disease
This study uses brain imaging (PET scans) to understand depression in people with Parkinson's disease. It may also test a depression treatment called ketamine, but the main goal is to see how the brain changes with depression.
New Haven, ConnecticutAges 40–80 - NCT06231563RecruitingPhase 2
Ketamine for depression in veterans with Parkinson's
This study tests if ketamine can help treat depression in veterans with Parkinson's disease. It involves several in-person and remote visits, and you will need to avoid certain medications and cannabis for a short time before and during some visits.
San Francisco, CaliforniaAges 40–80
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Common questions
- Are there clinical trials for parkinson disease dementia?
- Yes. Clin2 currently lists 315 recruiting parkinson disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.