Clinical trials
Parkinson Disease Dementia clinical trials
Below are recruiting parkinson disease dementia clinical trials, each written for real people, not researchers. We’re tracking 319 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06857851Recruiting
Deep brain stimulation study for movement in Parkinson's
This study looks at whether adjusting deep brain stimulation (DBS) can improve how you see and move. DBS uses a device implanted in your brain to help control Parkinson's symptoms. This research aims to find better settings for that device to improve your coordination and daily function.
Cleveland, OhioAges Any age - NCT06753331RecruitingPhase 1/Phase 2
Study of DSP-1083 for Parkinson's disease
This trial tests a new treatment called DSP-1083 for people with Parkinson's disease whose symptoms are not well controlled with standard medications. The study will check if it is safe and if it helps improve movement and daily function.
Lexington, KentuckyAges 40–72 - NCT06874803Recruiting
Acupuncture and moxibustion for early Parkinson's motor symptoms
This trial tests whether acupuncture and moxibustion can help improve movement symptoms in people with early to moderate Parkinson's disease. It is designed to see if adding these treatments to your regular care offers extra benefits.
Beijing, Beijing MunicipalityAges 30–80 - NCT07064005RecruitingPhase 1
Boosting glutathione with a supplement in Parkinson's
This study tests whether a supplement called gamma-glutamylcysteine can increase levels of a natural antioxidant called glutathione in the brain of people with Parkinson's. If you are between 50 and 80 and have mild cognitive symptoms, this trial may help researchers understand a new way to support brain health.
Pittsburgh, PennsylvaniaAges 50–80 - NCT07080775RecruitingPhase 1
Testing a new injection for Parkinson's disease
This trial tests an injection called XS411CN for people with Parkinson's disease whose current medications are not working as well as before. The goal is to see if it is safe and tolerable.
Beijing, Beijing MunicipalityAges 50–75 - NCT07244640Recruiting
Detecting Parkinson's through eye scans
This study uses a special eye camera to see if early signs of Parkinson's and similar movement disorders can be spotted in the retina. It may help doctors diagnose these conditions sooner and more easily.
Hangzhou, ZhejiangAges 40–80 - NCT07313176Recruiting
Long-term study of levodopa gel for advanced Parkinson's
This trial tests how well a levodopa-entacapone-carbidopa intestinal gel works over time for people with advanced Parkinson's disease who have severe motor fluctuations and dyskinesia. It's for those who've already used a similar treatment (foslevodopa) for at least a month and whose doctor decided to start this gel.
A Coruña, A CoruñaAges 18 years+ - NCT07606547Recruiting
Swallowing Strength Training for Parkinson's Disease
This study tests whether a mouth and throat muscle-strengthening device called EMST helps people with Parkinson's disease who have difficulty swallowing. Stronger throat muscles may make swallowing safer and easier.
MünsterAges 18 years+ - NCT07569133Enrolling by invitation
Brain Stimulation to Reduce Depression in Parkinson's Disease
This study tests whether repetitive transcranial magnetic stimulation (rTMS)—a non-invasive brain stimulation technique—can safely reduce depressive symptoms in people with Parkinson's disease. If it works, it could offer a new treatment option for depression that often accompanies Parkinson's.
Daegu, Buk-guAges 40–90 - NCT06450418Recruiting
Digital app for speech and health monitoring
This trial tests a digital app that tracks speech and health changes. It is open to people with certain neurological conditions, their caregivers, and healthy volunteers.
EdinburghAges 16 years+ - NCT06596746Recruiting
Tracking markers for neurodegenerative diseases
This study tracks changes in people with Parkinson's disease, other movement disorders, or cognitive decline to find better ways to measure disease progression.
Cassino, FrosinoneAges 10 years+ - NCT02795052Recruiting
Stem cell treatment trial for nerve injury
This study tests whether bone-marrow stem cells can improve nerve function in people with nerve damage that usually doesn’t recover with current care. It also checks whether the treatment is safe and whether people can be followed over time with repeated nerve exams.
Westport, ConnecticutAges 18 years+ - NCT06120049RecruitingPhase 2/Phase 3
Comparing new PET scans for Parkinson's, MSA, Lewy body dementia, and Alzheimer's
This study tests if a new radioactive tracer called [18F]-MFBG can help doctors better distinguish between Parkinson's disease, multiple system atrophy (MSA), dementia with Lewy bodies, and Alzheimer's disease. It compares the new scan with two standard scans to see which is most accurate.
Ghent, GentAges 18–85 - NCT02194816Recruiting
Online survey study for people with Parkinson’s or Parkinsonism
This study looks at how changing certain factors over time relates to symptoms in Parkinson’s disease and related conditions. You may help researchers by completing longer online surveys every 6 months for 5 years.
Kenmore, WashingtonAges 19 years+ - NCT07218952Enrolling by invitation
Radiation therapy for Parkinson's disease
This trial tests if a targeted radiation therapy can help people with early-stage Parkinson's disease that affects only one side of the body. It aims to see if this treatment can slow down the disease and improve symptoms.
Rochester, MinnesotaAges 45–70 - NCT05824728RecruitingPhase 2
Levetiracetam for Parkinson’s psychosis with study partner support
This Phase 2 study tests whether AGB101 (levetiracetam) can reduce hallucinations, delusions, or related symptoms in people with Parkinson’s disease psychosis, while checking safety. You and a study partner will help with dosing and regular check-ins, including MRI scans.
Baltimore, MarylandAges 40–85 - NCT01799915Recruiting
Study of causes and progression of synuclein-related nerve conditions
This study follows people over time to better understand “synucleinopathies,” which are conditions that affect the nervous system as it develops and progresses. You may be asked to return for visits and report symptoms, especially those that happen when you stand up.
Boston, MassachusettsAges 18 years+ - NCT06875739Enrolling by invitation
Saliva test for early diagnosis of brain diseases
This study tests whether a saliva sample can help tell the difference between brain diseases like Alzheimer's, Parkinson's, and related conditions. By using a special laser technique, researchers hope to find a quick, non-invasive way to make an earlier and more accurate diagnosis.
CagliariAges 60–85 - NCT07314190Enrolling by invitation
Blood tests for brain diseases and mental health conditions
This study looks at blood tests to help diagnose and track brain diseases (like Alzheimer's) or mental health conditions. It compares patients to healthy volunteers to find better ways to detect and monitor these illnesses.
BarcelonaAges 18 years+ - NCT05514106Enrolling by invitationPhase 4
MIBG heart scan study for aging and neurologic conditions
This Phase 4 study tests how an iodine-based heart scan (a special imaging test) works in people with certain neurologic diagnoses and aging-related conditions. It may help researchers better understand the heart-brain connection in these disorders and improve future care.
Rochester, MinnesotaAges 40–90 - NCT01453127Enrolling by invitationPhase 4
DaTscan scan for aging and movement brain conditions
This trial uses a special brain scan called DaTscan to study how certain brain conditions change with aging and over time. It may help researchers better understand movement and other neurodegenerative conditions and who may benefit from future treatments.
Rochester, MinnesotaAges 40–90 - NCT05450237Enrolling by invitation
Testing thinking and memory questionnaires in people with brain injury
This study checks how well certain questionnaire and testing tools work for people who have brain damage from neurologic conditions and ongoing brain inflammation. It may help future patients by improving which tests are most accurate and easy to use.
Pozzilli, IserniaAges 18–80 - NCT06597942RecruitingPhase 1/Phase 2
Deep TMS for Alzheimer's disease
This trial tests a non-invasive brain stimulation technique called deep repetitive TMS on a brain region linked to memory. It aims to see if this treatment can improve symptoms in people with mild-to-moderate Alzheimer's disease.
Los Angeles, CaliforniaAges 60–100 - NCT07142044RecruitingPhase 1/Phase 2
Testing EC5026 for Parkinson's disease
This study tests a new oral medication called EC5026 for Parkinson's disease. It aims to see if the drug is safe and if it might help control symptoms when added to your current levodopa treatment.
Sacramento, CaliforniaAges 50–80
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Common questions
- Are there clinical trials for parkinson disease dementia?
- Yes. Clin2 currently lists 319 recruiting parkinson disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.