Clinical trials
Parkinson Disease, Idiopathic clinical trials
Below are recruiting parkinson disease, idiopathic clinical trials, each written for real people, not researchers. We’re tracking 209 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06872203Enrolling by invitation
Sensing brain signals with new DBS leads during surgery
This study tests a new way to measure brain signals during Deep Brain Stimulation (DBS) surgery for Parkinson's disease. It uses special leads that can sense brain activity, which may help doctors better adjust the stimulation in the future.
Aurora, ColoradoAges 18–75 - NCT06705517Recruiting
Mediterranean diet study for Parkinson's disease
This trial tests whether a Mediterranean diet can help people with Parkinson's disease. You would either follow your usual diet or switch to a Mediterranean diet for six months and provide blood and stool samples.
Varese, VareseAges 40–85 - NCT06814431Recruiting
Cancer risk in parkinson's patients with GBA gene mutation
This study looks at whether people with Parkinson's disease who have a specific gene change (GBA mutation) have a higher chance of developing cancer. It will help doctors understand the link between these conditions.
BrindisiAges 18 years+ - NCT06680830RecruitingPhase 2
Testing NEU-411 for early Parkinson's with LRRK2 gene change
This trial tests an experimental drug called NEU-411 for people with early Parkinson's disease who have a specific genetic change (LRRK2). It aims to see if the drug can slow the disease progression.
Sun City, ArizonaAges 40–80 - NCT06508801Recruiting
Blood flow restriction to improve balance in Parkinson's
This study tests whether gently restricting blood flow to your legs during exercise can help improve balance for people with Parkinson's disease. You will do simple leg exercises while wearing a special cuff, which may strengthen muscles and improve steadiness.
San Antonio, TexasAges 40–85 - NCT06341829Enrolling by invitation
Vision and emotions in Parkinson's disease
This study explores how Parkinson's disease affects visual and emotional abilities. It aims to understand these challenges better to improve future care.
Messina, MessinaAges 18–90 - NCT06084533Enrolling by invitation
Brain inflammation imaging in Parkinson's disease
This study uses a special PET scan to look for signs of brain inflammation in people with Parkinson's disease. It aims to understand how inflammation relates to Parkinson's and may help in developing new treatments.
St Louis, MissouriAges 50 years+ - NCT05962489Recruiting
Sleep-focused DBS therapy study for Parkinson’s disease
This study looks at a sleep-focused approach to brain stimulation (DBS) in people with Parkinson’s disease. You may be able to join if you’re planning or scheduled for specific DBS surgery at the University of Minnesota and have the needed brain imaging.
Minneapolis, MinnesotaAges 21 years+ - NCT05864157Recruiting
Targeted training to improve walking in Parkinson’s disease
This study tests a targeted motor training approach to improve walking (gait) in people with Parkinson’s disease. You may be considered if your walking is affected but you can already walk steadily for 10 minutes without help.
Chapel Hill, North CarolinaAges 50–80 - NCT05539196Recruiting
Registry for Exablate treatment in Parkinson’s with medication problems
This trial is a real-world registry that follows people with Parkinson’s who are planning to get an Exablate 4000 procedure (a focused ultrasound treatment) for one-sided symptoms that are difficult to control with medication. It mainly checks outcomes and safety over time, helping doctors understand how well this treatment works in everyday care.
Baltimore, MarylandAges 30–99 - NCT04991831Recruiting
Registry study for Exablate thalamotomy in tremor-dominant Parkinson’s
This study follows people who are getting an Exablate procedure to treat medication-resistant, tremor-dominant Parkinson’s. It aims to track safety and outcomes in real-world care after the treatment is approved.
Miami, FloridaAges 30–99 - NCT04731246Recruiting
Eye-movement testing in people with early Parkinson’s
This study uses video recordings of your eye movements to learn more about Parkinson’s disease. It may help researchers better tell Parkinson’s apart from other movement conditions and understand how the disease affects the brain early on.
MonacoAges 18 years+ - NCT04566341Enrolling by invitation
Study gut problems in Parkinson’s and changes in gut nerves
This study looks at how digestive (gut) problems happen in people with Parkinson’s and whether there are related changes in the nerve tissue in the digestive tract. It may help researchers better understand the cause of these symptoms and find new ways to monitor or treat them.
Boston, MassachusettsAges 40–85 - NCT07138560RecruitingPhase 4
Study of IPX-203 for Parkinson's disease (BOOST-PD)
This study tests a new formulation of carbidopa-levodopa (IPX-203) to see how well it works for people with Parkinson's disease. It uses a wearable device to measure movement and aims to improve “off” time, when symptoms return between doses.
Cleveland, OhioAges 40 years+ - NCT07863219Recruiting
Cognitive effects of a 10-week exercise program for Parkinson's disease
This trial tests whether a 10-week program combining exercise and other activities can improve thinking and memory in people with Parkinson's disease.
Ghent, Oost-VlaanderenAges 18 years+ - NCT07842926Recruiting
Radiofrequency heat therapy for leg stiffness in Parkinson's disease
This study tests a therapy called capacitive-resistive radiofrequency (a type of heat treatment) to see if it helps reduce stiffness in the legs of people with Parkinson's disease. You may receive this therapy during a session, and we will measure how it affects your movement and walking.
Zaragoza, ZaragozaAges 55–90 - NCT07798271Recruiting
Optimizing deep brain stimulation for Parkinson's disease
This study is for people with Parkinson's disease who already have a deep brain stimulator (a device that sends electrical pulses to the brain) and still have motor fluctuations (times when symptoms come and go). The researchers want to see if adapting the device's settings can better control symptoms than the current standard settings.
Davis, CaliforniaAges 18 years+ - NCT07721688Recruiting
Different frequency brain stimulation for Parkinson's disease
This study tests a new, noninvasive brain stimulation technique (called temporal interference stimulation) given at different frequencies. It aims to improve Parkinson's symptoms by gently stimulating the brain area involved in movement.
Guangzhou, GuangdongAges Any age - NCT06646510Recruiting
Electrical stimulation for resting tremors in Parkinson's
This trial tests whether gentle electrical stimulation to the skin (called sensory electrical stimulation) can help reduce resting tremors in people with Parkinson's disease. Resting tremors are shaking that happens when your muscles are relaxed, like when your hands are in your lap.
GizaAges 45–60 - NCT07618728Recruiting
Community Exercise Program for Parkinson's Disease
This study tests whether a group exercise program designed for Parkinson's disease patients can be safely and practically run in a community setting. The program combines different types of movement and exercise to help improve function and quality of life.
Alcorcón, MadridAges 18 years+ - NCT06710574RecruitingPhase 4
Probiotics for sleep problems in Parkinson's disease
This study tests whether taking probiotics can improve REM sleep behavior disorder (RBD) in people with Parkinson's disease. You will receive either a probiotic supplement or a placebo, and researchers will use brain scans to see how it affects your symptoms.
BeijingAges 40–85 - NCT07585409Recruiting
Physical Activity for Parkinson's Disease Patients
This study tests whether physical activity (like exercise or movement) can help people with Parkinson's disease feel better and move more easily. Researchers want to understand how activity affects Parkinson's symptoms and quality of life.
StockholmAges 18 years+ - NCT07536542Recruiting
Dual-Task Training for Hand and Arm Function in Parkinson's
This study tests whether doing hand and arm exercises while performing a second task (like counting or listening) can improve movement and strength in people with Parkinson's disease. The goal is to help you move more smoothly and regain function in your hands and arms.
AnkaraAges 40–65 - NCT06751797Recruiting
Balance confidence and fear of falling in Parkinson's
This study looks at how confident people with Parkinson's are in their balance and whether fear of falling (kinesiophobia) affects their daily life. The goal is to better understand these factors so that future treatments can help people stay active and safe.
Istanbul, BeylikdüzüAges 50–80
Hear when a new Parkinson Disease, Idiopathic trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for parkinson disease, idiopathic?
- Yes. Clin2 currently lists 209 recruiting parkinson disease, idiopathic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease, idiopathic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease, idiopathic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.