Clinical trials
Parkinson s Disease clinical trials
Below are recruiting parkinson s disease clinical trials, each written for real people, not researchers. We’re tracking 740 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05444907Recruiting
Testing treatment response in DBS-related mania in Parkinson’s
This study is looking at people with Parkinson’s who developed mania (a high-energy mood episode) after deep brain stimulation (DBS) was turned on or its settings were changed. It may help doctors better understand why this happens and how to manage it safely.
LisbonAges 18 years+ - NCT05518617Recruiting
Imaging study for inherited Parkinson’s using PET, SPECT, and spinal fluid
This trial tests how well special brain scans (PET/SPECT) and spinal fluid tests can show changes in people with inherited (genetic) Parkinson’s. It may help researchers understand what’s happening in the brain and improve how these conditions are measured.
Exeter, DevonAges 25–80 - NCT05557864Recruiting
Brain scan study for Parkinson’s patients with deep brain stimulators
This study looks at how the location of a deep brain stimulator in Parkinson’s disease affects movement problems. It mainly uses advanced 7T brain imaging to compare brain activity and motor symptoms.
Minneapolis, MinnesotaAges 21–89 - NCT05576818RecruitingPhase 3
Synbiotic add-on for people with Parkinson’s disease
This trial tests whether adding a synbiotic (a mix of probiotics and prebiotics) along with standard Parkinson’s medicines can improve symptoms or health outcomes. It’s mainly for adults with Parkinson’s disease at earlier to mid-stages who take dopamine replacement therapy.
Tanta, El GharbiaAges 45–65 - NCT05773885Recruiting
Telerehab sessions for people with Parkinson’s disease
This study tests whether rehab delivered through the internet (“telerehabilitation”) can help people with Parkinson’s disease. You may be able to do therapy from home, while the team monitors your function during the study.
Cassino, FrosinoneAges 30–80 - NCT05968703Recruiting
Deep brain stimulation study for mild memory trouble in Parkinson’s
This trial looks at a specific type of deep brain stimulation (DBS) to see if it can help people with Parkinson’s who have mild cognitive problems (mild memory/thinking changes). You may also be asked to temporarily stop Parkinson’s medications around research visits to measure effects more clearly.
Stanford, CaliforniaAges 21–80 - NCT06002581Recruiting
Using brain stimulation to slow Parkinson's disease progression
This study tests if a non-invasive brain stimulation technique called rTMS (repetitive Transcranial Magnetic Stimulation) can slow down Parkinson's disease by improving slow-wave sleep. It aims to help people with mild to moderate Parkinson's who are stable on their medication.
Shanghai, Shanghai MunicipalityAges 50–80 - NCT06028529Recruiting
Exoskeleton trial for mobility in Parkinson's
This study tests a wearable robotic exoskeleton called Keeogo to see if it can help people with Parkinson's walk better and move more easily. You would come to the Richmond VA Medical Center for visits and try walking with the device.
Richmond, VirginiaAges 18–90 - NCT06231563RecruitingPhase 2
Ketamine for depression in veterans with Parkinson's
This study tests if ketamine can help treat depression in veterans with Parkinson's disease. It involves several in-person and remote visits, and you will need to avoid certain medications and cannabis for a short time before and during some visits.
San Francisco, CaliforniaAges 40–80 - NCT06324422Recruiting
Exercise for Parkinson's fatigue
This trial tests if a structured exercise program can reduce fatigue in people with Parkinson's disease. It may help you feel less tired and improve daily function.
Aarhus, Central JutlandAges 40 years+ - NCT06402955RecruitingPhase 2
Imaging depression in Parkinson's disease
This study uses brain imaging (PET scans) to understand depression in people with Parkinson's disease. It may also test a depression treatment called ketamine, but the main goal is to see how the brain changes with depression.
New Haven, ConnecticutAges 40–80 - NCT06405334Recruiting
Study on balance problems in Parkinson's disease
This study looks at how Parkinson's disease affects balance and the brain signals involved. It aims to understand why some people with Parkinson's have trouble with balance, and in part of the study, it will look at how deep brain stimulation (a device that sends electrical impulses to the brain) affects balance.
Minneapolis, MinnesotaAges 18 years+ - NCT06442033Recruiting
Exercise and genetics to slow Parkinson's
This trial studies whether a regular aerobic cycling program can slow the progression of Parkinson's disease. Researchers will also look at how genetics may affect the benefits of exercise.
Cleveland, OhioAges 18 years+ - NCT06476912Recruiting
Balance exercise and nerve stimulation for Parkinson's with anxiety
This study tests whether combining balance exercises with a gentle nerve stimulation (called vagus nerve stimulation) can help people with Parkinson's disease who also have anxiety. The goal is to see if this combination improves walking and balance.
TaipeiAges 40–85 - NCT06530290RecruitingPhase 2
Mirtazapine for anxiety in Parkinson's disease
This trial tests whether mirtazapine, a medication often used for depression and anxiety, can reduce anxiety symptoms in people with Parkinson's disease. It is for patients with mild to moderate Parkinson's who also experience anxiety.
TehranAges 18 years+ - NCT06538298RecruitingEarly Phase 1
Exercise program with games for Parkinson's
This study tests a fun exercise program that includes games for people with Parkinson's disease. It aims to see if this type of program can help improve movement and daily life.
Ventura, CaliforniaAges 40–80 - NCT06565195RecruitingPhase 1
Study of an experimental treatment for early Parkinson's disease
This study tests an experimental treatment (LY3962681) for people with early Parkinson's. It aims to see if the treatment is safe and can slow the disease. You must have a confirmed diagnosis, be in good overall health, and have stable medication use.
Austin, TexasAges 30–80 - NCT06087926Recruiting
TMS for apathy in Parkinson's disease
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help improve apathy, or loss of motivation, in people with Parkinson's disease. You must have had symptoms for at least 4 years and be on stable Parkinson's medications.
Chapel Hill, North CarolinaAges 55–80 - NCT06634641RecruitingPhase 4
Clozapine and immune function in Parkinson's disease
This trial tests whether clozapine, a medication for psychosis in Parkinson's disease, affects the immune system. It involves regular blood monitoring to help keep patients safe.
SalouëlAges 18 years+ - NCT06665113Recruiting
Ear nerve stimulation for early Parkinson's disease
This trial tests whether a non-invasive nerve stimulation device (taVNS) worn on the ear can protect brain cells and slow Parkinson's disease progression in early-stage patients. It is for people who have been diagnosed within the last 3 years and are already on standard medication.
Nanjing, JiangsuAges 55–75 - NCT07641556Recruiting
Remote training for arm movement in Parkinson's disease
This study tests whether doing arm-coordination exercises remotely (via video call) with dual tasks—like moving your arms while counting—can help improve hand function in people with Parkinson's disease. You'd do sessions at home with a caregiver's help.
AnkaraAges 40 years+ - NCT01682668Recruiting
Deep brain stimulation study for Parkinson movement problems
This study looks at how deep brain stimulation (an implanted brain device) affects Parkinson’s symptoms, especially movement problems like freezing, slowness, or involuntary movements. It may help people whose symptoms are not fully controlled by standard Parkinson medicines.
Paris, PARISAges 18–70 - NCT06857851Recruiting
Deep brain stimulation study for movement in Parkinson's
This study looks at whether adjusting deep brain stimulation (DBS) can improve how you see and move. DBS uses a device implanted in your brain to help control Parkinson's symptoms. This research aims to find better settings for that device to improve your coordination and daily function.
Cleveland, OhioAges Any age - NCT06753331RecruitingPhase 1/Phase 2
Study of DSP-1083 for Parkinson's disease
This trial tests a new treatment called DSP-1083 for people with Parkinson's disease whose symptoms are not well controlled with standard medications. The study will check if it is safe and if it helps improve movement and daily function.
Lexington, KentuckyAges 40–72
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Common questions
- Are there clinical trials for parkinson s disease?
- Yes. Clin2 currently lists 740 recruiting parkinson s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.