Clinical trials
Parkinsonism clinical trials
Below are recruiting parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 732 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07213219Recruiting
PET-MRI scan for Parkinson's with sleep behavior disorder
This trial uses a combined PET and MRI scan to study the brain's reward system in people with Parkinson's disease who also have REM sleep behavior disorder (RBD). It aims to understand how the brain changes and may help guide future treatments.
Clermont-FerrandAges 45–80 - NCT07213856Recruiting
Dietary help for constipation in Parkinson's disease
This study tests whether a special diet can help improve constipation symptoms in people with early-stage Parkinson's disease. It aims to see if changing what you eat can make bowel movements more regular and comfortable.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07221266Recruiting
Exercise programs for people with Parkinson’s
This study tests how different exercise programs affect movement, fitness, and quality of life in people with Parkinson’s disease. It may help you find an exercise routine that improves your symptoms.
El Paso, TexasAges 50 years+ - NCT05182892Recruiting
Reducing speech side effects from DBS using speech recordings
This study tests whether automated analysis of your speech can help reduce speech problems caused by deep brain stimulation (DBS) in Parkinson’s disease. It may help your team adjust DBS settings to improve how you speak while keeping Parkinson symptoms controlled.
PragueAges 18 years+ - NCT06893055Recruiting
Strength and endurance training for Parkinson's
This study tests a circuit training program that combines strength and endurance exercises to see if it helps people with Parkinson's disease improve their movement and daily function.
Prague, PragueAges 18–75 - NCT05576818RecruitingPhase 3
Synbiotic add-on for people with Parkinson’s disease
This trial tests whether adding a synbiotic (a mix of probiotics and prebiotics) along with standard Parkinson’s medicines can improve symptoms or health outcomes. It’s mainly for adults with Parkinson’s disease at earlier to mid-stages who take dopamine replacement therapy.
Tanta, El GharbiaAges 45–65 - NCT06573762Recruiting
Home monitoring for Parkinson's disease
This study uses a Fitbit to track movement and symptoms from home. It is for people who are newly referred or recently diagnosed with Parkinson's disease.
Iowa City, IowaAges 50–110 - NCT07207122Recruiting
Focused ultrasound for Parkinson's cognitive symptoms
This trial tests whether a non-invasive ultrasound treatment, called transcranial focused ultrasound stimulation (tFUS), can improve movement and thinking in people with Parkinson's disease. It may be an option for those whose symptoms are not well controlled by medication alone.
Tucson, ArizonaAges 22–80 - NCT07207057RecruitingPhase 3
Platform trial testing multiple drugs for Parkinson's disease
This trial tests several experimental drugs at once to find new treatments for Parkinson's disease. If you have Parkinson's and take medication, you may be able to join and help speed up research.
LondonAges 30 years+ - NCT06232772Recruiting
Biomarkers for early Parkinson's diagnosis
This study looks for new markers in the blood or other samples to help diagnose Parkinson's disease earlier. It compares people with Parkinson's, related conditions (like multiple system atrophy or progressive supranuclear palsy), and healthy volunteers to find differences.
Nanning, GuangxiAges 18–80 - NCT05152394RecruitingPhase 1
Testing cord stem cell exosome treatment for Parkinson’s safety
This Phase 1 study tests whether a treatment made from donated umbilical cord “exosomes” is safe in people with Parkinson’s disease. It mainly looks at side effects and safety, and could help guide future treatments if it proves tolerable.
St John'sAges Any age - NCT07187739Recruiting
Mediterranean diet for Parkinson's with deep brain stimulation
This study tests whether a Mediterranean diet can improve nutrition in people with Parkinson's disease who have had deep brain stimulation surgery. It may help you maintain better nutrition and overall health.
Ankara, AnkaraAges 45–64 - NCT07190404Recruiting
Thinking skills program for Parkinson's disease
This study tests a program to help people with Parkinson's disease who are noticing problems with their memory or thinking. The program teaches strategies to manage daily thinking challenges.
St Louis, MissouriAges 50 years+ - NCT07176494Recruiting
Revision of Deep Brain Stimulator in Parkinson's Disease
This study is for people with Parkinson's disease who need to have their deep brain stimulator (a device that sends electrical pulses to control movement) replaced or adjusted. The researchers want to learn the best way to do this procedure safely.
Ankara, Yenimahalle\AnkaraAges 40–85 - NCT07176091Enrolling by invitation
Magnetic brain stimulation for Parkinson's disease pain
This trial tests a special type of magnetic brain stimulation (called TMS) to see if it can help with Parkinson's disease and the pain that often comes with it. You must have had Parkinson's for at least 3 years, have frequent pain, and be on stable medications.
Suzhou, JiangsuAges 40–80 - NCT07182058RecruitingPhase 1/Phase 2
Brain stimulation device for Parkinson's motor symptoms
This trial tests a wearable brain stimulation device (tES) that delivers gentle electrical currents to your head to help improve Parkinson's motor symptoms like tremor, stiffness, or slowness. The treatment is done at home with remote video monitoring, and may offer a non-medication option to help with movement.
Cleveland, OhioAges 18–80 - NCT07175922Recruiting
A study of gene changes in people with Parkinson's disease
This study looks at how the csgA gene changes over time in people with Parkinson's disease, especially if they have stomach or bowel issues. It aims to help understand how these changes might relate to symptoms.
LeidenAges 18–80 - NCT07166757RecruitingPhase 1/Phase 2
Study of XS411 for early-onset Parkinson's disease
This trial tests a new treatment called XS411 for people with early-onset Parkinson's disease (age 50 or younger at diagnosis). It is for those whose motor symptoms are not well controlled with standard medications and who may benefit from a neurosurgical procedure.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07174310RecruitingPhase 3
Prasinezumab for early Parkinson's disease
This study tests a new medication called prasinezumab, given through a vein (IV), to see if it can slow the progression of early-stage Parkinson's disease. It is for people who are on only one Parkinson's medication and have not yet developed motor complications.
Birmingham, AlabamaAges 50–85 - NCT07170475RecruitingPhase 1
Study of febuxostat and inosine for Parkinson's disease
This trial tests whether a combination of two supplements, febuxostat and inosine, can help people with Parkinson's disease. It aims to see if this treatment is safe and may improve symptoms.
Toyoake, Aichi-kenAges 18–80 - NCT05778617RecruitingPhase 3
Ambroxol to Slow Parkinson’s Disease Progression
This trial studies whether ambroxol (or a placebo) can slow the progression of Parkinson’s disease. It may help by aiming to change how the disease develops over time.
BirminghamAges 35–75 - NCT06438419Recruiting
Brain activity in Parkinson's during movement with DBS
This study records brain activity during movement in people with Parkinson's who have a special deep brain stimulation (DBS) device. It aims to understand how brain rhythms relate to movement, which could improve future treatments.
BordeauxAges 18–75 - NCT07157345RecruitingPhase 1
Testing PDR-001 for Parkinson's Disease
This trial tests a new drug, PDR-001, to see if it can safely remove harmful proteins from the brain in people with early Parkinson's disease. It may help slow down the disease.
Shanghai, Shanghai MunicipalityAges 40–65 - NCT07163156Enrolling by invitation
Prolactin and inflammation in Parkinson's severity
This study looks at whether prolactin (a hormone) and inflammation markers in blood and saliva are related to the severity of Parkinson's disease. It may help identify new ways to track the disease.
Çanakkale, MerkezAges 18 years+
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Common questions
- Are there clinical trials for parkinsonism?
- Yes. Clin2 currently lists 732 recruiting parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.