Clinical trials
Parkinsonism clinical trials
Below are recruiting parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 735 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07738107RecruitingPhase 1/Phase 2
Study of ATR 1072 for PRKAG2 syndrome
This trial tests a new medicine called ATR 1072 for people with PRKAG2 syndrome, a genetic heart condition. It aims to see if the drug is safe and can help manage symptoms.
Kansas City, MissouriAges 18–65 - NCT05826548Recruiting
Telerehabilitation program for memory, Parkinson’s, and stroke needs
This trial studies a home-based exercise and training program delivered by telerehabilitation (remote care) for people with mild cognitive impairment, Parkinson’s disease, or stroke. It may help improve day-to-day thinking and movement skills by supporting you with structured practice from home.
Lido, VeneziaAges 18–85 - NCT04635436Recruiting
Split-walking training for one-sided leg weakness when walking hurts
This trial tests whether a “split gait” walking training method can improve walking balance and how you move when you have one-sided leg problems and pain or limitations when walking. It may help reduce walking difficulties by training your stepping pattern safely.
Milan, MIAges 18–70 - NCT06631742Recruiting
Exergaming for dementia: a fun exercise trial
This trial tests whether playing interactive video games that combine exercise and thinking challenges (called 'exergaming') can help people with dementia. It aims to see if this fun way to move and think can improve memory, daily function, and quality of life.
Wetzikon, Canton of ZurichAges Any age - NCT05822258Recruiting
Tracking freezing while walking in Parkinson’s using motion sensors
This study tests motion-sensor devices (small inertial measurement units) to detect moments when walking suddenly “freezes” in Parkinson’s disease. If you have freezing episodes, it may help researchers measure them more accurately and support better monitoring.
Rennes, Brittany RegionAges 18 years+ - NCT07720765Recruiting
Using eye scans to study brain diseases
This trial uses a type of eye scan (OCT) to look at the retina in people with brain conditions like multiple sclerosis, Alzheimer's, Parkinson's, or migraines. It aims to see if these scans can help doctors learn more about the disease and monitor it over time.
Milan, MilanoAges 18 years+ - NCT06596187Recruiting
Study of muscle tightness in spinal cord injury and Parkinson's
This study looks at muscle tightness (hypertonia) in people with spinal cord injury, Parkinson's disease, and healthy volunteers. It aims to better understand and measure different types of stiffness to improve treatments.
TaoyuanAges 20 years+ - NCT07701785Recruiting
Brain stimulation study for Parkinson's with mild memory issues
This trial tests a type of brain stimulation called iTBS on an area of the brain that may help with thinking and memory problems in people with Parkinson's disease and mild cognitive impairment. If you qualify, you and your caregiver would take part in sessions and answer questions about your daily life.
Charleston, South CarolinaAges 50–85 - NCT07697664Recruiting
Memory and thinking through exercise in aging
This study looks at whether light-to-moderate physical activity (like walking or stretching) can help memory and thinking in middle-aged and older adults. People with normal thinking, mild memory problems, or Parkinson's disease may join if they aren't already very active.
Atlanta, GeorgiaAges 18–79 - NCT07700862Recruiting
Deep brain stimulation for tremor-dominant Parkinson's disease
This trial compares two ways to place electrodes in the brain to reduce tremors. It may help people with Parkinson's disease whose main symptom is shaking.
ShanghaiAges 18–80 - NCT06197698Recruiting
Parkinson's and gut-brain connection study
This study is looking at how the bacteria in your gut might affect your brain in Parkinson's disease. It involves two types of brain scans to see differences between people with Parkinson's and healthy volunteers.
DouliuAges 20 years+ - NCT04607174Recruiting
Test knee muscle activation in people with nerve or movement disorders
This study checks how well your knee muscles “turn on” during guided, controlled knee movements. It may help researchers understand movement problems and improve testing or therapies for neuromotor (nerve/movement) disorders.
Milan, MIAges 18–70 - NCT07682311Recruiting
Adjusting brain stimulation automatically for Parkinson's
This study tests a new way to adjust deep brain stimulation (DBS) automatically during the day to better control Parkinson's symptoms. It is for people who already have a Percept DBS device but still have motor fluctuations.
San Francisco, CaliforniaAges 25–75 - NCT07640542RecruitingEarly Phase 1
Brain imaging study for Parkinson's and MSA patients
This early-stage research trial tests a new brain-imaging tracer called [11C]MODAG-005 to help doctors better understand Parkinson's disease (PD) and multiple system atrophy (MSA). You would undergo PET/CT and MRI scans twice, a few weeks apart, to see how reliable the imaging is.
Tübingen, Baden-WurttembergAges 50–75 - NCT07640555RecruitingEarly Phase 1
Brain imaging study for Parkinson's and related movement disorders
This research study tests a new type of brain scan (called a PET scan) that may help detect early signs of Parkinson's disease and similar conditions. You'll receive the scan and may have a spinal tap to check for specific protein markers.
New Haven, ConnecticutAges 50–80 - NCT07642908Recruiting
Brain imaging study of Parkinson's disease with LRRK2 gene mutations
This research study uses advanced MRI brain imaging to understand how a specific gene mutation (LRRK2) affects certain brain chemicals in people with Parkinson's disease. The goal is to learn more about how this genetic form of Parkinson's works, which could help develop better treatments.
Ann Arbor, MichiganAges 45 years+ - NCT07635823Recruiting
Adaptive deep brain stimulation for Parkinson's disease
This study tests a new type of deep brain stimulation (DBS)—a surgical treatment that uses electrical pulses to help control Parkinson's symptoms. Unlike standard DBS, this system adapts automatically to your body's needs. You may qualify if you've never had DBS surgery or if you've had it before and are willing to switch to the new device.
Hefei, AnhuiAges 18 years+ - NCT07604116RecruitingPhase 1
Testing a new imaging agent for Parkinson's and related conditions
This study tests an investigational imaging agent called SST001, which may help doctors see a protein linked to Parkinson's disease (PD) and multiple system atrophy (MSA) in the body. It will be given to healthy volunteers and patients with PD or MSA to check safety, how it spreads, and how the body handles it.
Wuxi, JiangsuAges 18 years+ - NCT05995782RecruitingPhase 1
Testing safety of FB418 in healthy people
This trial studies a new drug called FB418 to see if it's safe and how the body handles it. It first tests single doses in younger healthy men, then multiple doses, and also includes an optional group for healthy older adults.
SeoulAges 19 years+ - NCT07595666Enrolling by invitation
New PET scanner versus standard PET for head and neck imaging
This study compares a newer PET/CT scanner (called NeuroEXPLORER) with standard PET/CT scanners for imaging the head and neck region. The goal is to see if the new scanner provides better or clearer images to help diagnose conditions.
Leuven, Vlaams-BrabantAges 4 weeks+ - NCT07586501Enrolling by invitation
Brain Health and Immune System Study in Older Adults
This research study examines how the brain's immune system changes in older adults with memory problems, Parkinson's disease, or normal aging. By understanding these changes, researchers hope to better understand neurodegeneration and develop new treatments.
Yantai, ShandongAges 55–75 - NCT07580612Recruiting
Home-based AI system for detecting freezing of gait in Parkinson's
This study tests an artificial intelligence system that detects freezing of gait—sudden, involuntary pauses while walking—using sensors you wear at home. The goal is to better understand and eventually help manage this common Parkinson's symptom.
LeuvenAges 18 years+ - NCT07574164Recruiting
Brain Stimulation to Reduce Tremor in Parkinson's or Essential Tremor
This trial tests a new type of brain stimulation called closed-loop TMS that automatically adjusts to help reduce tremor in people with Parkinson's disease or essential tremor. The goal is to see if this technology can better control shaking than standard treatments.
Oxford, OxfordshireAges 18 years+ - NCT07569120Recruiting
Brain Chemistry and Aging: Healthy and Parkinson's Study
This research uses brain imaging scans to study how a chemical messenger in the brain (called noradrenaline) changes as people age and in Parkinson's disease. The goal is to better understand how this brain system works and may help develop future treatments.
BronAges 20–80
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Common questions
- Are there clinical trials for parkinsonism?
- Yes. Clin2 currently lists 735 recruiting parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.