Clinical trials
Participation clinical trials
Below are recruiting participation clinical trials, each written for real people, not researchers. We’re tracking 2,239 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07219602RecruitingPhase 3
Study of obicetrapib and ezetimibe for diabetes and metabolic syndrome
This trial tests a combination medication (obicetrapib plus ezetimibe) taken daily to lower cholesterol and triglycerides in people with type 2 diabetes or metabolic syndrome who are already on standard cholesterol treatment. It may help reduce heart risks.
Sun City West, ArizonaAges 18 years+ - NCT07219719RecruitingPhase 1
Brain stimulation study for healthy adults
This study uses a new type of brain stimulation (temporal interference) to see if it can safely change brain activity. It is for healthy adults who want to help researchers learn more about how the brain works.
Madison, WisconsinAges 18–50 - NCT07220655Recruiting
How focused ultrasound affects thinking and brain activity
This trial uses low-intensity focused ultrasound (LIFU) and brain scans to see how it affects thinking. It may help researchers find new ways to treat brain conditions.
Minneapolis, MinnesotaAges 18 years+ - NCT07220824Recruiting
Study of guselkumab for psoriatic arthritis in real-world care
This study is testing how well guselkumab works for people with psoriatic arthritis who are starting it in everyday medical practice. Researchers want to see if the drug helps reduce joint swelling and tenderness, and if it can improve enthesitis (pain where tendons attach to bone).
BariAges 18 years+ - NCT07221149RecruitingPhase 2/Phase 3
Pumitamig vs Nivolumab for untreated stomach or esophagus cancer
This trial compares two treatments for people with advanced stomach, gastroesophageal junction, or esophageal cancer that has not been treated before. One group gets pumitamig plus chemotherapy, the other gets nivolumab plus chemotherapy. The goal is to see which combination works better.
Phoenix, ArizonaAges 18 years+ - NCT07221838RecruitingPhase 4
Steroid Tapering Study for Myasthenia Gravis on Ravulizumab
This study is for people with generalized myasthenia gravis who are already on ravulizumab and a daily steroid. It aims to see if the steroid dose can be safely lowered over time.
Chicago, IllinoisAges 18 years+ - NCT07222631RecruitingPhase 1/Phase 2
Study of SB-4826 for advanced solid tumors or lymphomas
This trial tests a new drug, SB-4826, for people with advanced solid tumors or certain types of lymphoma that have not responded to standard treatments. The goal is to see if the drug is safe and effective, either alone or with another drug called rituximab.
La Jolla, CaliforniaAges 18 years+ - NCT07222709RecruitingPhase 1
Healthy volunteer study of oral ABBV-1042
This trial tests the safety of a new oral drug, ABBV-1042, in healthy adults. It helps researchers understand how the drug moves through the body and what side effects may occur.
Grayslake, IllinoisAges 18–55 - NCT07222917RecruitingPhase 2
Dapagliflozin with baxdrostat for kidney disease and high blood pressure
This trial tests if adding dapagliflozin to baxdrostat (a new blood pressure drug) reduces protein in urine better than baxdrostat alone in people with chronic kidney disease and high blood pressure. It aims to find a more effective way to protect kidney health.
Surprise, ArizonaAges 18 years+ - NCT07223047RecruitingPhase 1/Phase 2
Study of BMS-986523 for advanced solid tumors with KRAS changes
This trial tests an experimental drug (BMS-986523) alone or with other cancer treatments for people with advanced solid tumors that have a specific change in the KRAS gene. It aims to see if the drug is safe and effective.
Baltimore, MarylandAges 18 years+ - NCT07224074RecruitingPhase 1
Ketone drink and its effect on sleep and breathing
This study tests whether taking a ketone drink affects sleep and breathing in healthy adults. It is a small, early-stage trial at Johns Hopkins University.
Baltimore, MarylandAges 18–50 - NCT07225517RecruitingPhase 1
Safety study of BIIB145 in healthy adults
This study tests a new drug called BIIB145 in healthy volunteers to see if it's safe and how the body handles it. It helps researchers learn about the drug before testing it in people with specific conditions.
Austin, TexasAges 18–55 - NCT07226843RecruitingPhase 1
Study of a new drug for adults with certain blood cancers
This trial tests a new drug, LY4584180, for adults with several types of non-Hodgkin lymphoma who have already had at least two prior treatments. The goal is to see if the drug can help shrink tumors and stop the cancer from growing.
Scottsdale, ArizonaAges 18 years+ - NCT07227233RecruitingPhase 2
AI-guided retrial of CDK4/6 inhibitors for advanced breast cancer
This trial tests whether an artificial intelligence (AI) tool can help doctors decide if it is safe and effective to give you a second course of a CDK4/6 inhibitor drug (like palbociclib, ribociclib, or abemaciclib) plus hormone therapy for advanced (unresectable or metastatic) HR+/HER2- breast cancer. The goal is to only treat people whose cancer is likely to respond based on a special AI analysis of their tumor tissue.
La Jolla, CaliforniaAges 18 years+ - NCT07229313RecruitingPhase 1
Testing KIVU-107 in advanced solid tumors
This trial tests a new drug, KIVU-107, for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if this drug is safe and helps shrink or control the cancer.
Santa Monica, CaliforniaAges 18 years+ - NCT07229911RecruitingPhase 1
Study of TAK-781 in healthy people and PSC patients
This study tests an investigational drug called TAK-781 in healthy volunteers and in people with primary sclerosing cholangitis (PSC) who do not have cirrhosis. The study aims to see how the drug is processed by the body and whether it is safe.
Salt Lake City, UtahAges 18–68 - NCT07229937RecruitingPhase 2
Testing an experimental drug for high cholesterol
This study tests an experimental drug called HRS-1301 to see if it safely lowers LDL ("bad") cholesterol in people with high cholesterol. It is for adults who either already have artery disease or are at higher risk for it.
Harbin, HeilongjiangAges 18 years+ - NCT07230210Recruiting
Nutrition and exercise app study for muscle loss risk
This study tests if a smartphone program can help older adults at risk for muscle loss (sarcopenia) improve their strength and nutrition. You use an app to follow exercise and diet plans at home.
Hualien CityAges 65 years+ - NCT07230353RecruitingPhase 1
Plamotamab for moderate to severe rheumatoid arthritis
This trial tests a new treatment called plamotamab for people with moderate to severe rheumatoid arthritis (RA) who have not had enough relief from current treatments. The goal is to see if it is safe and to help control RA symptoms.
TbilisiAges 18 years+ - NCT07230496RecruitingPhase 1
Testing LAE103 alone or with LAE102 in healthy adults with extra weight
This trial is testing a new drug called LAE103 (and LAE102) in healthy people who are overweight or obese. It aims to see if the drug is safe and how the body processes it.
Brisbane, QueenslandAges 18–75 - NCT07231445RecruitingPhase 1
ZG006 with immunotherapy for extensive small cell lung cancer
This trial tests a new drug, ZG006, combined with standard immunotherapy (PD-1/PD-L1 inhibitors) for people with advanced small cell lung cancer that hasn't been treated before. The goal is to find out if this combination works better than the current standard care.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07231497RecruitingPhase 3
Cognitive training for early psychosis
This study tests whether a medication called modafinil can help improve thinking skills in people who have early psychosis. Participants will also do computer-based cognitive exercises. The goal is to see if combining the medication with training boosts memory, attention, and problem-solving.
Minneapolis, MinnesotaAges 18–35 - NCT07231679RecruitingPhase 1/Phase 2
Testing IGT-303 for kidney disease from diabetes
This study tests a new drug called IGT-303 for people with chronic kidney disease caused by type 2 diabetes. It aims to see if the drug is safe and can help protect kidney function.
Herston, BrisbaneAges 18–75 - NCT07231991RecruitingPhase 1
How the body processes Vepdegestrant in liver impairment
This study tests how the drug Vepdegestrant is processed by people with different levels of liver function. It aims to understand if liver problems change how the drug works, which can help doctors give the right dose.
Miami, FloridaAges 18–70
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Common questions
- Are there clinical trials for participation?
- Yes. Clin2 currently lists 2,239 recruiting participation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a participation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a participation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.