Clinical trials · North Carolina
Pediatrics clinical trials in North Carolina
We’re tracking 94 recruiting pediatrics studies with a site in North Carolina — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT06177639Recruiting
A new eye camera designed for children and babies
This trial is testing a new, more comfortable eye camera designed for children and babies. It takes wide-angle pictures of the back of the eye (retina) to see if it works better than current cameras. You or your child can join even if you have healthy eyes or an eye condition.
Durham, North CarolinaAges 4 weeks+ - NCT06186752Recruiting
Action planning test for teens with IBD
This study tests if a planning tool helps teenagers with Crohn's disease or ulcerative colitis manage their condition. It's for patients aged 13 to 19 who have had their diagnosis for at least 3 months and are seen at UNC.
Chapel Hill, North CarolinaAges 13–19 - NCT06332534RecruitingPhase 3
Upadacitinib in children with moderate to severe Crohn's disease
This study tests an oral pill called upadacitinib for children with moderate to severe Crohn's disease that hasn't responded well to other treatments. It aims to see if the medicine can reduce inflammation and improve symptoms safely.
Chapel Hill, North CarolinaAges 2–17 - NCT06428175Recruiting
Hospital-to-home support for children with complex needs
This study tests a program to help children with complex medical needs and their families transition smoothly from the hospital to home. It focuses on improving communication and support during that critical time.
Chapel Hill, North CarolinaAges Up to 18 years - NCT05156398RecruitingPhase 3
Rimegepant to prevent migraine attacks in children
This trial studies whether rimegepant can reduce how often migraine attacks happen in children and teens. It also looks at safety and how well the treatment fits day-to-day life and school activities.
Fayetteville, North CarolinaAges 6–17 - NCT06639984RecruitingPhase 2
Psyllium for kids with IBS
This study tests if psyllium, a fiber supplement, helps reduce belly pain and other symptoms in children with irritable bowel syndrome (IBS). It may be an option if standard treatments haven't worked well.
Durham, North CarolinaAges 12–17 - NCT06654752Recruiting
Simpler treatment for lung flare-ups in kids with CF
This study tests a streamlined approach to managing sudden lung symptoms (pulmonary exacerbations) in children with cystic fibrosis. It aims to see if a simpler treatment plan works as well as standard care, which could mean less time in the hospital and fewer disruptions to daily life.
Chapel Hill, North CarolinaAges 3–18 - NCT06697808Recruiting
Using Ultrasound to Detect Brain Issues in Children
This trial tests if a portable ultrasound can spot brain problems in children needing a head CT in the emergency room or ICU. If effective, it could offer a faster, radiation-free way to check for issues.
Charlotte, North CarolinaAges Up to 18 years - NCT06739122RecruitingPhase 3
A study of dulaglutide for children with type 2 diabetes
This trial tests if a weekly injection of dulaglutide (Trulicity) can help children with type 2 diabetes control their blood sugar when used together with metformin and/or insulin. It may be an option for kids who are overweight.
Chapel Hill, North CarolinaAges 10–17 - NCT06751238RecruitingPhase 1
Secukinumab for children with psoriatic arthritis
This study tests a drug called secukinumab (given through an IV) in children with juvenile psoriatic arthritis. The goal is to see how well it works and if it's safe over time, for up to 6 years.
Charlotte, North CarolinaAges 2–17 - NCT06814795Recruiting
Medically tailored meals for kids with cancer
This study tests whether providing specially designed meals to children undergoing chemotherapy can help with taste changes and improve their eating. It is for kids ages 12 to 17 who are being treated at UNC Chapel Hill and plan to have at least two more chemo cycles.
Chapel Hill, North CarolinaAges 12–99 - NCT06841575Recruiting
Better eye imaging for children and adults at Duke
This study tests a new camera that automatically adjusts to take clear pictures of the back of the eye. It aims to improve retinal imaging for healthy adults, adult eye clinic patients, and children seen at Duke Eye Center.
Durham, North CarolinaAges 1 month+ - NCT06847282Recruiting
Motor skills study for children with FSHD
This study looks at how children with FSHD move and function over time. It uses walking tests and optional MRI scans to understand muscle changes. Your child's participation could help researchers learn more about FSHD progression in kids.
Durham, North CarolinaAges 5–17 - NCT06904261RecruitingPhase 3
Study of migalastat for children with Fabry disease
This trial tests if the oral drug migalastat is safe and works for children aged 2 to under 12 with a specific type of Fabry disease. It may be an option if your child has not been on enzyme therapy recently and has a compatible gene variant.
Charlotte, North CarolinaAges 2–11 - NCT06941389Recruiting
Comparing stem cell transplant vs standard therapy for sickle cell disease
This study compares two treatment approaches for children with sickle cell anemia: a stem cell transplant from a matched family donor versus continuing regular disease-modifying medicines. It aims to see which treatment works better over time.
Charlotte, North CarolinaAges 3–20 - NCT07124078RecruitingPhase 2
Study of axatilimab vs. best available therapy for chronic GVHD in children
This trial tests a new drug called axatilimab against the best available standard treatments for children with chronic graft-versus-host disease (cGVHD) that has not responded to at least two prior treatments. It aims to find a better option for managing this condition.
Charlotte, North CarolinaAges 2–17 - NCT01109394Recruiting
Help study tumors with sample testing and a research biology library
This study collects tumor (or related) samples to analyze their genes and build a shared research “biobank.” It may help researchers understand cancers better for future diagnosis and treatments.
Charlotte, North CarolinaAges 4 weeks+ - NCT02418442Recruiting
Kid rheumatic disease registry study for follow-up care
This is an observational study that follows children and teens with rheumatic (joint/inflammatory) diseases to better understand how they develop and are cared for over time. You may help by letting the study contact your family in the future and by completing study tasks as needed.
Chapel Hill, North CarolinaAges Up to 21 years - NCT02559778RecruitingPhase 2
Precision treatment trial for children with advanced neuroblastoma
This Phase 2 trial studies a targeted treatment approach for children and young adults with advanced neuroblastoma (a childhood cancer). It may help by using lab-tested cancer features to guide therapy after initial treatment and transplant.
Charlotte, North CarolinaAges Up to 22 years - NCT02708134Recruiting
Study of CPR quality in children and young adults
This trial looks at how well CPR (chest compressions) is done during an emergency resuscitation in children and young adults. The goal is to understand what helps improve care during life-saving resuscitation.
Chapel Hill, North CarolinaAges birth–18 years - NCT07581938Recruiting
Early Dental Screening for Sleep Problems in Kids
This study uses a smartphone app and a wearable device to check for early signs of sleep-disordered breathing—a condition where breathing stops briefly during sleep—in children ages 8–13. The goal is to catch dental and jaw problems that might lead to sleep issues before they become serious.
Chapel Hill, North CarolinaAges 8–13 - NCT05127954Enrolling by invitationPhase 3
Long-term migraine tablet study for kids and teens ages 6–17
This study follows kids and teens who already took part in an earlier migraine medication study to check long-term safety and comfort with oral ubrogepant tablets. It may help families understand whether this migraine tablet is safe to keep using over time.
Charlotte, North CarolinaAges 6–17
Pediatrics trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting pediatrics studies listed above.
- University of North Carolina at Chapel Hill · 5 studies
- Levine Children's Hospital · 3 studies
- Carolinas Medical Center/Levine Cancer Institute · 2 studies
- Duke University · 2 studies
- Duke University Medical Center · 2 studies
- Levine Cancer Institute · 2 studies
- UNC Children's Hospital · 2 studies
- Adams School of Dentistry
What taking part in a pediatrics study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pediatrics trials in other states
Common questions
- Are there pediatrics clinical trials in North Carolina?
- Yes. We're currently tracking 94 recruiting pediatrics studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pediatrics study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pediatrics trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pediatrics studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.